tig
mL1481c
PROBABLE TRIGGER FACTOR (TF) PROTEIN TIG
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1783575 – 1784984
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1481c_tig_dna
GCCCGTGAAAAGCAGTGTCGAGCAGTTGAACCCTACTCGGGTGCGTATCAACGTGGAAGTACCTTTTACAGAGCTTGAGCCGGATTTTCAGCGGGCCTACAAAGAGCTGGCCAGACATGTGCAGCTGCCCGGTTTCCGGCCCGGGAAAGTTCCTGCGCGATTGCTGGAGGCCCGTTTTGGTCGGGAGACGCTGCTCGATCAGGTCGTCAACGAAGCCATGCCCAGTCGGTACGGGCAGGCGCTGGCGGAGTCTGAGGTCCAACCGATCGGCCAGCCCGAAATAGAGGTGATCAGAAAGGAGTACGGTCAGGATCTGGCTTTCACCGTCGAAGTTGAGGTACGCCCCAAGATCGCACTTCCGGATTTCAGCACATTGAAGGTTGTTGTGGATCCGGTCGAGGTCAGCACCGATGATGTCGAGGCAGAGTTGCGGTCGTTGCGTGCCAGGTTCGGCACTCTGATCGGCGTGGACCGACCTGTGGCGCTCGGTGACTTTGTCTCGATTGATTTGTCGGCCACCATCAATGGCGAGAAGGTGCCGAACGCCGATGCGGAGGGGCTGTCTCATGAGGTCGGCTACGGCCGGCTTATCGCAGGTCTCGACGATGCGCTCGTCGGTTTGTCCGCTGGTGAGTCGCGAGTCTTCACCACCCAGTTAGCGACCAGCAAACACGCCGGGCAAGACGCAGAGGTCATCGTCACCGTCAAGTCGGTCAAGGAACGCGAATTGCCGGAGCCGGATGACGAATTCGCGCAACTGGTCAGCGAGTTCGACACCATGGCAGAACTACGGGCCAATCTCGGGGATCAGGTCCGTAAGGCTAAGTACGCCCAGCAAGCGGAGAAAATCCGTGACGCGGCTGTGGACGCTTTGCTCGAGCGGGTAGATGTGCCATTGCCGGAAGGGATTGTGCAAGCCCAGTTCAATAATGCCCTGCATGACGCGCTCAGCGGCCTGGGCCACGACGAAGCCAAGTTCGCCGAGGTGCTCGCTGAGCGTGGGTCGTCGCGCGAGGAGTTCGAGGCTGAAGCGCGTAGCGCTGCCGAGAGAGATGTCACGAGGCAACTGCTGTTGGATGTAGTGGCTGACGACCAGAAGATCCAGGTGGGTCAGGATGACCTGAACGAACGCTTGCTCGCCACGTCTCAGCAATACGGCGTCGACGCACAGCAGCTGTTTGGCTTCTTGCGGGAAAACAACCGGTTATCGTCCTTGGTTACTGACGCGCGGCGCAGGCTGGCGGTCGCAGCTGTGGTCGAGGCGGCTACGTTCACCGATAGTGACGGAAACACGATAGACACCAGTGAATTTTTCGGTAAGCATGCCCAAAGCGATAAGGCCGACCAGAAGACCGAAGAAGCAGATCCGAACAGTGATGCCATCGATGAAGAGGTCGACGAGGCCGCGGA

Protein Sequence 

>ML1481c_Tig_protein
AREKQCRAVEPYSGAYQRGSTFYRA_AGFSAGLQRAGQTCAAARFPARESSCAIAGGPFWSGDAARSGRQRSHAQSVRAGAGGV_GPTDRPARNRGDQKGVRSGSGFHRRS_GTPQDRTSGFQHIEGCCGSGRGQHR_CRGRVAVVACQVRHSDRRGPTCGAR_LCLD_FVGHHQWREGAERRCGGAVS_GRLRPAYRRSRRCARRFVRW_VASLHHPVSDQQTRRARRRGHRHRQVGQGTRIAGAG_RIRATGQRVRHHGRTTGQSRGSGP_G_VRPASGENP_RGCGRFARAGRCAIAGRDCASPVQ_CPA_RAQRPGPRRSQVRRGAR_AWVVARGVRG_SA_RCRERCHEATAVGCSG_RPEDPGGSG_PERTLARHVSAIRRRRTAAVWLLAGKQPVIVLGY_RAAQAGGRSCGRGGYVHR__RKHDRHQ_IFR_ACPKR_GRPEDRRSRSEQ_CHR_RGRRGRG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Tig with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

47 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Tig

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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