fbiC
mL1492c
PROBABLE F420 BIOSYNTHESIS PROTEIN FBIC
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1797616 – 1800207
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1492c_fbiC_dna
TTGATTGTGGGGAAGTTACACCAAAGTGTCGCTGATTGAAAGCCAGGAGCCCATCGCTCTTTCTCGCCCTGTCGTTCCACCCAAGCCTAATACGTCGGCGCTGCGGCGGGTATTGCGCCGAGCTCGAGACGGTTTCGCGCTGAATATCGATGAGGCGGTCGTTGCGATGACCGCACGTGGTGAGGATCTGGCTGACCTTTGTGCCAGTGCTGCTCGGGTACGCGACGTAGGTCTCGAAACGGCTGGGCGACGCGGTGCAGACGGCCGGTTGCCGATTACCTATTCGAGGAAGGTGTTCATCCCCGTCACCCATCTGTGCCGCGACAGCTGCCACTACTGCACTTTCGTCACCGCCCCAGACATGCTGCGTACCCAAGGTGCTGGGATGTACTTGGAACCCAACGAAATTCTCAATCTAGCTCGTCGTGGGAGTGAACTTGGTTGCAAGGAGGCACTATTCACCCTCGGTGACCGGCCTGAGGATCGCTGGGCGCAAGCTCGTGACTGGCTCGCTGAACGGGGTTATGATTCCACGTTGTCCTATTTGCGGGCGATGGCGATTCGCGTGTTGGAGGAGACCGGCCTATTGCCGCATTTGAATCCTGGCGTGATGAGTTGGTCTGAGCTGTCGCGGCTCAAACCGGTGGCGCCTTCGATGGGTATGATGCTGGAGACGACGTCACGACGATTATTCGAAACAAAAGGCCTCGCGCACTACGGCAGTCTGGACAAAGATCCGACGGTGCGGTTGCGGGTGCTGACTGATGCGGGTCGGTTGTCCATACCGTTCACCACCGGTCTGCTGGTCGGCATCGGCGAGACGTTGGCCGAGCGTGCCGATACGTTGCACGAGATCCGCAAGTCGAACAAGGAGTTCGGCCATGTCCAGGAAGTAATCGTGCAGAATTTCCGGGCCAAGGAACACACTGCGATGGCTGCGGTTCCGGATGCCAGGATCGAGGATTACCTAGCAACCGTGGCTGTTGCTCGGCTGGTACTGGGTCCAGCTATGCGTATTCAGGCGCCGCCGAACCTGGTGTCGCGCGAGGAGTGTCTCGCGTTGGTTACTGCCGGTGTTGACGACTGGGGCGGTGTCTCACCACTGACACCCGACCATGTCAATCCGGAACGACCCTGGCCTGCTTTGCATGAATTGGCTGCTGTCACAGCGGAGGCCGGTTATACCCTGGTGCAGCGGTTGACTGCCCAACCTAAATACGTGCAGGCAGGTGCCGCATGGATCGACCCACGAGTGCGGGGTCATGTTGTGGCACTGGCTGATCCGGTGACCGGCTTGGCTCGCGATGTCAATCCGGTCGGCATGCCCTGGCAGGAGCCCGACGATGTGGAGTCCGCCGGTCGGATGGATATCAATACAGCGATCGACACCGAGGGCCGCAACACCGAAGCCCGTAGCGACCTCGACAGCGCATTCGGTGATTGGGAATCAATCCGTGCCCACGTGCACGAGTTGGCCGACTGCGCCCCGGAGCGCATCGATACCGATGTGCTCGCTGCACTTCGCTCAGCTGAGCGTGATCCCGCCGGTTGCACTGACGACGAGTATCTGGCGTTGGCCACCGCCGACGGTCCTGCACTGGAAGCTGTTACTGCACTTGCAGATTCGTTGCGCCGGGATGTGGTCGGTGATGATGTGACGTTCGTGGTGAATCGTAACATTAACTTCACCAATATCTGTTACACCGGCTGTCGGTTCTGTGCGTTCGCCCAACGCAAGGGTGACACCGATGCCTACTCGTTGTCTAGAGAGGAGGTCGCTGAACGCGCATGGGAGGCACACGTCCAGGGTGCCACCGAGGTATGTATGCAGGGTGGTATCGACCCCGAGCTACCGGTCACTGGCTACGTCGATCTGGTGCGCGCCGTCAAAACCCGGGTCCCTTCGATGCATGTGCACGCGTTTTCCCCGATGGAGATCGCCAACGGTGTGGCCAAGAGTGGTTTTAGTATTCGTGAGTGGCTGATCAGTTTGCGTGAGGCTGGCTTGGATACCATTCCCGGCACCGCCGCCGAAATCCTGGATGATGAAGTGCGCTGGGTACTAACTAAGGGCAAGTTGCCGACGTCGATGTGGATCGAGATCGTCACCACGGCCCATGAGGTGGGTTTACGCTCTTCGTCGACCATGATGTACGGCCATGTCGACGGGCCACGCCACTGGGTGGCTCACCTACAAGTCCTGCGCGATATCCAGGATCGCACCGGTGGCTTCACCGAATTTGTGCCATTGCCTTTCGTGCACCAGAATTCGCCGTTGTACCTGGCCGGAGCAGCTCGTCCGGGGCCCACCCATCGTGACAACCGTGCCGTTCATGCCCTGGCGCGAATTATGCTGCACGGCCGTATCTCTCACATTCAAACTAGCTGGGTGAAGCTTGGCGTGGAGCGCACGCAGGCAATGCTTAACGGGGGCGCCAACGACCTAGGAGGCACGTTGATGGAGGAGACCATCTCGCGGATGGCCGGTTCTGAATACGGTTCCGCCAAGACCGTCGCCGAGTTGATAGCGATCGCGGAGGGCATCGGCCGCACCGCCCGCCAGCGCACCACCACCTACGCCCTGCGAGGGGC

Protein Sequence 

>ML1492c_FbiC_protein
LIVGKLHQSVAD_KPGAHRSFSPCRSTQA_YVGAAAGIAPSSRRFRAEYR_GGRCDDRTW_GSG_PLCQCCSGTRRRSRNGWATRCRRPVADYLFEEGVHPRHPSVPRQLPLLHFRHRPRHAAYPRCWDVLGTQRNSQSSSSWE_TWLQGGTIHPR_PA_GSLGASS_LAR_TGL_FHVVLFAGDGDSRVGGDRPIAAFESWRDELV_AVAAQTGGAFDGYDAGDDVTTIIRNKRPRALRQSGQRSDGAVAGAD_CGSVVHTVHHRSAGRHRRDVGRACRYVARDPQVEQGVRPCPGSNRAEFPGQGTHCDGCGSGCQDRGLPSNRGCCSAGTGSSYAYSGAAEPGVARGVSRVGYCRC_RLGRCLTTDTRPCQSGTTLACFA_IGCCHSGGRLYPGAAVDCPT_IRAGRCRMDRPTSAGSCCGTG_SGDRLGSRCQSGRHALAGARRCGVRRSDGYQYSDRHRGPQHRSP_RPRQRIR_LGINPCPRARVGRLRPGAHRYRCARCTSLS_A_SRRLH_RRVSGVGHRRRSCTGSCYCTCRFVAPGCGR__CDVRGES_H_LHQYLLHRLSVLCVRPTQG_HRCLLVV_RGGR_TRMGGTRPGCHRGMYAGWYRPRATGHWLRRSGARRQNPGPFDACARVFPDGDRQRCGQEWF_YS_VADQFA_GWLGYHSRHRRRNPG__SALGTN_GQVADVDVDRDRHHGP_GGFTLFVDHDVRPCRRATPLGGSPTSPARYPGSHRWLHRICAIAFRAPEFAVVPGRSSSSGAHPS_QPCRSCPGANYAARPYLSHSN_LGEAWRGAHAGNA_RGRQRPRRHVDGGDHLADGRF_IRFRQDRRRVDSDRGGHRPHRPPAHHHLRPARG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FbiC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

58 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FbiC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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