typA
mL1498c
POSSIBLE GTP-BINDING TRANSLATION ELONGATION FACTOR TYPA (TYROSINE PHOSPHORYLATED PROTEIN A) (GTP-BINDING PROTEIN)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1805545 – 1807431
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1498c_typA_dna
CGACGTGCCATTCCGCAATGTCGCCATTGTCGCGCACGTCGACCACGGCAAAACCACGCTGGTTGACGCGATGCTACGCCAGTCCGGCGCGCTACACGAACGCGGTCAAGTCCAGGAACGCGTGATGGATACCGGTGACTTGGAACGGGAAAAAGGCATCACAATCCTGGCCAAAAACACGGCCGTACATTGTCACAATTCGGACGGTACGGTGACGGTGATCAATGTTATCGACACGCCTGGCCATGCCGACTTCGGCGGTGAAGTGGAACGCGGGCTGTCTATGGTGGATGGGGTGTTGTTGCTGGTCGATGCCTCCGAAGGGCCGCTGCCGCAGACGCGGTTCGTGCTGCGCAAGACGCTGGCTGCGCATTTGCCGGTGATTCTGGTAGTTAACAAGACAGATCGTCCCGACGCACGCATCGCCGAGGTGGTGGAAGCCAGCCACGACCTGTTGCTTGACGTCGCATCCGATCTTGACGAGGAAGCGGCTGCGGCCGCCGAGCGTGCGCTGGGTCTGCCGACGTTGTATGCGTCCGGGCGTGCCGGCATCGCCAGCACCGAGCAGCCTGCTGACGGTGCTGTGCCCACGGGCGACAACCTCGACCCCTTGTTCGACGTGCTGATGGAGCACATCCCGTCGCCGAAGGGTGACCCCGAAGCGCCGTTGCAGGCGTTGGTGACTAACTTGGACGCCTCGGCCTTCCTCGGTCGGCTTGCTTTGGTCCGCATCTATAACGGCAAGCTGCGCAAGGGGCAGCAGGTGGCTTGGATGCGTGAAGTGGACGGGCTGCCTGTCACCACCGACGCCAAGATCACTGAGTTGCTGGTCACCAAAGGTGTCGAGCGCAGCACTACAGAGGAAGCGACGGCAGGGGATATCGTAGCCGTAGCGGGACTGCCCGAGATCATGATCGGTGACACGTTGGCCGATCCCGAGCATGCTCATGCACTACCGCGTATCACCGTAGACGAGCCGGCTATCTCGGTGACGATCGGCACCAATACCTCGCCCCTGGCGGGCAAGGTGTCGGGCCACAAGTTGACTGCGCGGATGGTTCGTGGCCGCCTGGACGCTGAGTTGGTCGGCAACATCTCGATCCGTGTGGTGGACATAGGACGGCCCGATGCGTGGGAGGTGCAGGGCCGAGGTGAGCTTGCGTTGGCAGTGCTTGTTGAGACGATGCGTCGGGAAGGGTTCGAGCTTACGGTCGGCAAGCCGCAGGTGGTCACCCGTACGATCGATGGCAAACTGCACGAACCATTCGAGGTGATGACGATCGACTGTCCCGAGGAGTTCGTCGGCGCGATCACCCAGTTGATGGCCGGCCGTAAGGGCCGCATGGAGGAGATGGCCAACCATGCTGTGGGCTGGGTGCGAATGGACTTCATCGTGCCCAGCCGTGGCTTGATTGGCTTCCGTACCGACTTCCTCACCCTCACACGCGGCACCGGTATTGCTAACGCTGTGTTCGACAGCTATCGGCCGTGGGCCGGTGAGATCCGAGCCAGGGATACGGGGTCGCTGGTTTCCGACCGGCCGGGTACTATTACGCCGTTTGCTCTGCTCCAACTTGCCGATCGGGGTCAGTTCTTCGTGTCGCCTGGCCAGGACACTTACCAAGGTATGGTCGTCGGAATCAACCCTCGTCCGGAAGATCTCGATATCAATGTTACTCGTGAGAAAAAGCTGACCAACATGCGGTCATCGACCGCCAATGTCATCGAGACGTTGACCAAACCGCTCGAGCTGGACCTGGAGCGGGCGATGGAATTCTGCTCGTTCGACGAATGTGTTGAGGTGACCCCTGAGATTGTGCGGGTGCGCAAGATCGAACTGGAATCCAACGCCCGGGCCCGAGGCCGGGCCCGAGCCAAGGTTCGAGG

Protein Sequence 

>ML1498c_TypA_protein
RRAIPQCRHCRARRPRQNHAG_RDATPVRRATRTRSSPGTRDGYR_LGTGKRHHNPGQKHGRTLSQFGRYGDGDQCYRHAWPCRLRR_SGTRAVYGGWGVVAGRCLRRAAAADAVRAAQDAGCAFAGDSGS_QDRSSRRTHRRGGGSQPRPVA_RRIRS_RGSGCGRRACAGSADVVCVRACRHRQHRAAC_RCCAHGRQPRPLVRRADGAHPVAEG_PRSAVAGVGD_LGRLGLPRSACFGPHL_RQAAQGAAGGLDA_SGRAACHHRRQDH_VAGHQRCRAQHYRGSDGRGYRSRSGTARDHDR_HVGRSRACSCTTAYHRRRAGYLGDDRHQYLAPGGQGVGPQVDCADGSWPPGR_VGRQHLDPCGGHRTARCVGGAGPR_ACVGSAC_DDASGRVRAYGRQAAGGHPYDRWQTARTIRGDDDRLSRGVRRRDHPVDGRP_GPHGGDGQPCCGLGANGLHRAQPWLDWLPYRLPHPHTRHRYC_RCVRQLSAVGR_DPSQGYGVAGFRPAGYYYAVCSAPTCRSGSVLRVAWPGHLPRYGRRNQPSSGRSRYQCYS_EKADQHAVIDRQCHRDVDQTARAGPGAGDGILLVRRMC_GDP_DCAGAQDRTGIQRPGPRPGPSQGSR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TypA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

65 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TypA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.