npdA
mL1511
Probable NAD-dependent deacetylase NpdA (Regulatory protein SIR2 homolog)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1821253 – 1821960
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1511_npdA_dna
TAGTGCTTAGCGGCGCGGGTATCTCCGCGGAAAGCGACGTGCCGACATTCCGCGACGACAAGAATGGATTGTGGGCACGCTTCGATCCTTACCAGCTGTCCAGCACGCAAGGCTGGCAGCGCAACCCTGAGCGGGTCTGGGGGTGGTACTTGTGGCGCCACTACCTGGTAGCCAACGTCAAACCCAACGATGGCCACCGCGCTATAGCCGCCTGGCAGGAGCAGATCGAGGTTAGCGTCATCACCCAAAATGTTGACGATTTGCACGAGCGCGCCGGCAGCACGCCGGTGCACCATCTGCACGGCAGCCTTTTCAAATTTCATTGTGCCCGCTGCAATGTGGCCTACACCGGTGCACTTCCCGATATGCCCGAACCCGTACTAGAGGTGGACCCACCGGTCTGCTACTGCGGCGGTCTGATCCGGCCTGCCATCGTGTGGTTCGGTGAGCCATTACCCGATGAGCCGTGGCGACGCGCAGTGGAGGCGACCGAAACCACCGACGTCATGGTGGTGGTGGGGACATCCGCGATCGTCTACCCGGCGGCCGGGCTACCCGAGCTGGCACTGTCACGTGGTGCGGTTGTGATCGAAGTTAATCCCGAGCCCACACCGCTCACCAAGAACGCCACGATCAGCATTCGTGAGACTGCAAGTCAGGCATTGCCAGGACTGCTGCAGCGGCTTCCCGCCCTGTTGAAGTAGGCGT

Protein Sequence 

>ML1511_NpdA_protein
CLAARVSPRKATCRHSATTRMDCGHASILTSCPARKAGSATLSGSGGGTCGATTW_PTSNPTMATAL_PPGRSRSRLASSPKMLTICTSAPAARRCTICTAAFSNFIVPAAMWPTPVHFPICPNPY_RWTHRSATAAV_SGLPSCGSVSHYPMSRGDAQWRRPKPPTSWWWWGHPRSSTRRPGYPSWHCHVVRL_SKLIPSPHRSPRTPRSAFVRLQVRHCQDCCSGFPPC_SRR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding NpdA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

27 show weak predicted evidence for PPIs

View all pooled AlphaFold results for NpdA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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