eccE5
mL1537c
ESX CONSERVED COMPONENT ECCE5. PROBABLE MEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1853565 – 1854770
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1537c_eccE5_dna
AAAATAATGAAGGCTCAGCGCAGGTTGGGGTTGGCTTTGTCGTGGTCGCGTGTCACGACAGTATTTGTGGTCGCTATTGTCGTCCTCGTGTTGGCGAGCCATGTCCCAGAGTTATGGCAGGCCGGTCATCATGTCGCGTGGTGTGTAGGTGTTGGAATCACCGTCGTGGTCATGGTGCTGGTGTTGGTCAGCTACCATGGAATCACGCTGATGTCCGGTTTGGCCACGTGGGTATGGGATTGTTTTGCCGATCCGCGTGCCGCACTAGCGGCGGGGTGTACGCCCGCGATCGATCATCAGCGCCGCTTCGGACGCGACGTGGTTGGGGTGCGTGAGTACAAAGGCCGGCTCGTCACGGTGATCGCGGTGGACGATGGCGAAGACGACCCAGTGGGGCGACATAGGCATCGAACAACGCCGGCAGGTTTGCCGGTACAAGCTGTTGCCGATGGGTTGCGACAGTTCGATATCCGCCTCGATAGTATCGACATTGTCTCGGTGAAGATACGCCGCGGCGGCAATGCGGCCAAATTTTCAGCACTCGACAACTGGGGGTCCGAAGAGTGGGGGCTGGTGTGTGCTTGCCCGCCAACCTATCAGCGCTGTACCTGGCTGGTGTTGCGGATGAATCCGCAGCACAACGTTGTCGCGGTGGCTGCCCGGGATTCGCTGGCTTCGACGTTGGTGGCAGCTACTGAGCGACTTGCCCAAGATCTCGACGGACAAAACTGTGCGGCCCGGCCATTGGCCGCTGGTGAGCTGGCCGAGGTTGACAGTGCTGTGCTGGCCGATCTGGAGCCAACGTGGAGCTACCCGGGATGGCGCCATATCAAGTACGTCAATGGATTCGCGACTAGTTTCTGGGTGACGCCGTCAGACATCGATTCCGAAACACTGAATGAGCTGTGGCTGTCTGACCTCCCCGACATTAAGGCCACCGTGATCACGATCCGTCTCGCCAGTCGTAGTTGTCAAACCCGGCTGTCGGCGTGGGTGCGTCATCATAGCGAGACACGATTGTCCAAGGAGGCATGTAGAGGACTCAACCAACTGACCGGCCGTCAGTTAGCTGCGGTGCGTGCTAGCCTGCCGGCGCCGGCTACCCGGCCCGTATTGGTCGTGCCTAGCCGAGAGTTAAGCGACCATGATGAGCTGGTGCTGCCGGTGGGACAGGGGCGGGAAGGCTCAGCGAGCTTGTTTGCAGGG

Protein Sequence 

>ML1537c_EccE5_protein
KIMKAQRRLGLALSWSRVTTVFVVAIVVLVLASHVPELWQAGHHVAWCVGVGITVVVMVLVLVSYHGITLMSGLATWVWDCFADPRAALAAGCTPAIDHQRRFGRDVVGVREYKGRLVTVIAVDDGEDDPVGRHRHRTTPAGLPVQAVADGLRQFDIRLDSIDIVSVKIRRGGNAAKFSALDNWGSEEWGLVCACPPTYQRCTWLVLRMNPQHNVVAVAARDSLASTLVAATERLAQDLDGQNCAARPLAAGELAEVDSAVLADLEPTWSYPGWRHIKYVNGFATSFWVTPSDIDSETLNELWLSDLPDIKATVITIRLASRSCQTRLSAWVRHHSETRLSKEACRGLNQLTGRQLAAVRASLPAPATRPVLVVPSRELSDHDELVLPVGQGREGSASLFAG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccE5 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

48 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccE5

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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