eccD5
mL1539c
ESX CONSERVED COMPONENT ECCD5. PROBABLE MEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1856526 – 1858037
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1539c_eccD5_dna
AGAACGATGACGGCGGTAGCTGACGCGCCACGGACCGACATCGAGGGCACATCGTCACCCCGAGTGGTCGTAGTTGGAATCGTGGCTGGCGAGGGGGCCCAGATCAGCGTTTTGCTTGATGCCAACGCCCCGGTGTCAGTGATGACCGACCCACTGCTCAAAGTAATAAACAGTCGACTGTGTGAGCTTGGCGAAGGAACGCTTGAGCCTACCGGGCGCGGCAGATGGGCACTGTGCCTGATTGACGGCACCCCGTTGTGGCCCACCCAGTCGTTGACCGAGCAAGATGTCTACGACGGCGACCGATTGTGGATTCGGTTCATCGCCGACACCGAGCGTCGATCGCAGGTGATCGAGCATATCTCTACTGCGGTTTCGGCAAATCTCAGCAAGCGGTTCGCCGCGATAGACTCGATCGTTGCTGTGCAGGTCGGCGCGTTGATGGTGGCAACAGGTGTGTTGGCTTCGTCAGTTTTGTTGGTCTGGTGGCGTTGGCACCACGGTTTTTGGCTTTCGGTCATCTACGCCACAGTGATTGCGTTGCTGATATTGGTGATGTCCACGTTGGTGCTGATGCGGGCCACTACCCGGGAAGATCGACGCGCCGGTGACATCATGCTGCTGAGTGGGATTGCGCCAGTGACTGCGGCCGCAGCGGCCGCGCCACCTGGTCCGTTGGGGTCCCCGCACGCGGTGATGGGTTTCGGGGTGTTCGCGATTGCCGCGATGTTGGCCTTGCGATTCACCGGTCGTCAACTCAGTATTTACACTGCGATGATCACCATTTCCGTGGTGGTGGCGATCGCGAGCCTGGCACGGATGGTCGCGATGACCAGCGCGGTGACGCTGCTTTCCTGCGTAATGCTGGCCTGCGTGCTGCTCTACCATTGCGCACCAGCTCTGTCCCGCCGTTTGGCCGGCATTCGGCTACCGGTGTTTCCATCGGCCACCAGCCGGTGGGTGTTTGAAGCGCGACCCGATTTGCCTAACACGGTGGTGCGCTCCGACGGAGGCCCGCCGGTCTTGGAGGGGCCGGCGTCGGTGCGCGATGTGCTGCTGCAATCCGAACGTGCCCGGTCTTATTTATCGGGTTTACTCCTGGGGCTGGGCGTGTTGCTGGTGGTTTCACTTACCGCATTGAGCAACCCCCACGTCGGGCAGCGTTGGCTGCCGCTGTTGCTAGCTGGGTTTACCTCCGGTTTCCTACTATTGCGGGGCCGCTCGTATGTCGACCGCTGGCAAGCAATCACGTTGGCTGCGACTGCGGTACTCATCGTTGCTGCGGTGGTGGTGCGGTACGCGCTGGTTTTGTCGTCGCCGTTGGCGGTATCGATCGGGGCGGCAATCTTGGTTCTGCTGCCTGCTGCAGGGCTGATAGCTGCGGCGGTCGTGCCTAACACGATCTATAGCCCGCTGTTCCGCAAGCTTGTGGAATGGATCGAATACTTGTGCCTGGTACCTATTTTCCCCCTGGCATTGTGGTTGATGGATGTCTATACCGCGATCCGGTAC

Protein Sequence 

>ML1539c_EccD5_protein
RTMTAVADAPRTDIEGTSSPRVVVVGIVAGEGAQISVLLDANAPVSVMTDPLLKVINSRLCELGEGTLEPTGRGRWALCLIDGTPLWPTQSLTEQDVYDGDRLWIRFIADTERRSQVIEHISTAVSANLSKRFAAIDSIVAVQVGALMVATGVLASSVLLVWWRWHHGFWLSVIYATVIALLILVMSTLVLMRATTREDRRAGDIMLLSGIAPVTAAAAAAPPGPLGSPHAVMGFGVFAIAAMLALRFTGRQLSIYTAMITISVVVAIASLARMVAMTSAVTLLSCVMLACVLLYHCAPALSRRLAGIRLPVFPSATSRWVFEARPDLPNTVVRSDGGPPVLEGPASVRDVLLQSERARSYLSGLLLGLGVLLVVSLTALSNPHVGQRWLPLLLAGFTSGFLLLRGRSYVDRWQAITLAATAVLIVAAVVVRYALVLSSPLAVSIGAAILVLLPAAGLIAAAVVPNTIYSPLFRKLVEWIEYLCLVPIFPLALWLMDVYTAIRY

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccD5 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

58 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccD5

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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