eccC5
mL1543c
ESX CONSERVED COMPONENT ECCC5. PROBABLE MEMBRANE PROTEIN (SpoIIIE FAMILY)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1862221 – 1866378
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1543c_eccC5_dna
ACCTAAGTGAAACGTGGCTTTGCACGCCCGACGCCGGAAAAGGCTCCGGTTATCAGGCCGGAAAACATTGTCCTGCCAACACCTTTGAGTATTCCGCCACCAGAGGGCAAACCCTGGTGGGTTATCGTGATCGGTGTCGTAGTGATCGGTCTGGTGGGCGGCATGGTCGCCATGACGTTCGCCAGCGGTTCACGGGTGTTCGGGGGTGCAGGCTCAATTTTTCCGCTCTTCATGATCGGTGGTGTTGCGATGATGATGTTCAGTGGCCGAATGGGTGGGCAGCAGCAAATGAGCCGGCCGAAGCTGGACGCGATGCGCGCCCAGTTCATGTTGATGCTGGACATGCTGCGTGAGGCCGCGAATGAGTCGGCCGACAGCATGGACGCCAATTACCGGTGGTTCCACCCGGCGCCCACCACGTTGGCTGCTGCCGTGGGATCGTCCAGAATGTGGGAACGCAAACCTGATGGCAAGGACCTTAATTTCTGCGTTGTCCGAGTTGGCGTGGGCATGACGCGTCCCGAGGTGACGTGGGGCGAACCGCAGAATATGCCGACCGACATCGAGCTGGAGCCGGTAACCGGGAAGGCGCTACAGGAGTTCGGACGTTATCAAAGCATTGTTTACAACCTGCCAAAAATGGTTTCCCTACTGGTGGAACCCTGGTATGCGCTAATTGGGGACCGTGAGCAGACACTGGGATTAATGCGGTCAATCATTTGCCAGCTGACGTTTTCGCACGGTCCCGACCACGTGCAGATGGTGGTTGTTAGTTCCGATTTGGAGCAGTGGGACTGGGTCAAGTGGTTACCGCATTTTGGTGATCCCCGACGTCAGGACGCAGCAGGCAACGCGCGGATGGTGTACAGTTCGGTACGGGAATTCGCCACGGAACAAGCCGAATTGTTCGCCGGTCGAGGGTCGTTTACGCCGCGACACGCCAGTTCGTCGGCACAAACCCCGACACCTCACCACCTGATCGTTGCGGACGTCGTCGATCCGGAGTGGGAGTACGTGATCAGCGTCGAAGGTATCGACGGTGTGACGTTCTTCGACCTGACCGGCTCTTCGATGTGGACAGTAGTACCGAAGCGCACGTTGCGGTTTGACGAAAAAGGTGTGATCGACGCGCTGCCCCGCGATCGTGATACCTGGATGGTGATCGACGACAAGCCTTGGTTTTTCGCCCTCGCCGACCAACTCAGTTTCGCCGAAGCTGAAGAGTTCGCACAAAAGCTGGCGCACTGGCGGCCAGCCGAAGCCTACGAAGAGATCGGCCAGAGAGTAGCCCATATCGGTGCTCGAGATATCTTGTCTTACTACGGAATTGGAGATCCATCTGCGATCGACTTTGATGCGCTGTGGAACAGCCGTACCGATGCGATGGGCAAGTCGCGGTTGCGGGTACCGTTCGGCAATCGATCCGACAACGGTGAGCTGTTGTTTTTGGACATGAAATCGCTTGATGAAGGCGGCGATGGCCCGCACGGGGTGATGTCGGGGACAACTGGTTCGGGCAAATCGACGCTAGTGCGAACCGTGATCGAATCGTTGATGCTCGCTCATCCGCCGGAGGAGCTGCAGTTCGTGTTGGCAGATCTCAAAGGTGGGTCGGCGGTCAAGCCGTTCGCCGGTGTGCCGCATGTGTCTCGGATCATCACTGATCTTGAAGAAGACCAAGTGCTTATGGAGCGCTTCTTGGACGCGCTGTGGGGCGAAATCGCCCGCCGCAAAGCGGTCTGCGACAACGCCGGTGTAGACGACGCCAAGGAATACAACTCGGTGCGCACCAGGATGCGGGCGCGCGGCCAGGACATGCCGGCGTTGCCGATGCTAGTAGTGGTCATCGACGAGTTCTACGAGTGGTTCCGCATCGTACCGACGGCGGTCGACGTGCTTGACTCAATCGGCCGGCAGGGCCGCGCCTACTGGATTCATTTGATGATGGCGTCGCAGACCATTGAGAGCCGAGCTGAAAAGCTCATGGAGAACATGGGCTACCGTTTGGTTCTGAAAGCACGTACCGCTGGCGCGGCGCAGGCGGCCGGCGTGCCGAACGCGGTGAACCTGCCGGCTCAGGCGGGTCTGGGATATTTTCGTAAGAGCCTCGAAGACGTCATCCGGTTCCAGGCCGAGTTCCTGTGGCGGGACTACTTCCGCGGCGTCACTCTCGACGGCGAGGAACAGCCAGTGTTGGTGCACAACATCGACTATGTTCGACCGCAATTGTTTACCAACTTGTTCACGCCGCTCGAGGTGAGCGTAGGAGGCCCCGAGGTCGATGCGGAGGCTGTTTTTGCGAACGCTCAGGAATTCGACGAGGAGATCGCTGAGGAAGAAGCCGAGGGAGGGGTCAGGACACCGAAAATCGGTACGGTGATCATTGATCAGCTTCGCAGGATCGACTTTGAGCCCTACCGGTTGTGGCAACCCCCGCTGACCCAGCCCGTTGCCATCGACGATTTGGTCAACCGGTTTTTGGGTCACCCCTGGCAAAAGGACTACGGCTCGGCCAGGAATCTTGTGTTCCCCATTGGGGTCATTGACCGGCCATTCAAGCATGACCAGCCGGCGTGGACGGTTGACACTTCCGGACCCGGCTCCAACGTGTTGGTTCTGGGAGCCGGTGGTTCTGGAAAAACCACTGCGCTGCAGACAATTATCTGCTCGGCAGCACTGACTCACACCCCTGAACAGGTTCAATTCTACTGCCTGGGCTACAGCGGCACCGCGTTGACTACGGTGGCGCACTTGCCCCACGTCGGCGAGGTAGCAGGTCCTACAGATCCTTACGGTGTGCGCCGTACTGTGGCCGAACTGCTGGCACTGGTTCGCGATCGCAAACGTAGCTTTCTCGAACACGGGATTGCCTCGATGGAGGTGTTCCGGCGCCGCAAGTTCGGTGGTGAGCTGGGGCCGGTGCCTAATGATGGGTTCGGTGATGTCTACCTGGTGATCGACAACTACCGGGCACTGGTCGAAGAGAACGAGGTGCTTATTGAGCAGGTGAACCAGATCATAAACCAGGGCCCCTCGTTCGGCGTGCACGTGGTCGTCACTGCTGATCGCGAATCAGAGCTGAGGCCGCAGGTACGTAGCGGCTTCGGTTCCCGAGTCGAATTGCGCTTGGCTGCTGTGGAAGACGCCAAGTTGGTGCGTTCTCGGTTTGCCAAGGACGTTCCGGTTCAGTCGGGACGCGGCATGGTTGCGGTCAACTATGTCCGACTAGACAGCGATCCACAGGCGGGCTTGCACACGTTAGTCGCCCGGCCAGCGTTGGCCAATACCCCCGCTAACGTCTTCGAGTCCGACAGCGTGGTCGCACCGGTCAGCCGGTTGACGAGTGCCCAGGCCCCACCTGTGCGCCGGTTGCCGGCTCGTTTCGGTATGGAACAAGTGCGCGAGCGGGCTGTCCGAGACACCCGTCAAGGGGTTGGCGTAGGAGGAATAGCTTGGGCGATATCGGAATTGGATTTGCAACCGGTCTATCTGAACTTCGCTGAGAACGCGCATTTGATGATAACGGGTCGACGTGAATGTGGCCGGACCACAGTGCTGGCTACCATAATGTCCGAGATCGGTCGGCTCTATGCGCCGGGAGGTACTAGCGCACCACCGACGTCAGAACGCTCTGCGCAGGTATGGCTGATCGATCCGCGTCGTCAGCTGCTGACGATGCTGGGCTCCAACTATATGGAGAAGTTTGCCTACAACCTCGATGGCGTATCCGCCATGGTGGGTGAGTTAGCGGCGTTGTTGGCCAGCCGCGAACCGCCGCCTGATCTGTCCGCGGAAGAGTTATTGTCACGATCGTGGTGGAGCGGCCCGGAGATCTTCTTGATCATCGATGACATCCAGCAACTGCCGCCCAGTTTCGATTCACCGCTGCAGAAGGTTGTTCCCTGGGTGACTCGGGCCGGCGATGTCGGCTTGCATGTCATTGCCACCCGTACGTTCGGGGGGTGGTCTTCGGCGGGCAGTGACCCGATGTTGCGGGCCCTGCATCAGGCGAACGCACCATTGCTGGTTATGGACGCTGATCCCGATGAGGGTTTCATCCGCGGTAAGATGAAGGGCGGTCCTTTGCCCCGCGGCCGAGGCCTGTTGATGGCCGAAGACACCGGTGTGTTGGTGCAGGTGGCAGAGACCGATATGCGC

Protein Sequence 

>ML1543c_EccC5_protein
T_VKRGFARPTPEKAPVIRPENIVLPTPLSIPPPEGKPWWVIVIGVVVIGLVGGMVAMTFASGSRVFGGAGSIFPLFMIGGVAMMMFSGRMGGQQQMSRPKLDAMRAQFMLMLDMLREAANESADSMDANYRWFHPAPTTLAAAVGSSRMWERKPDGKDLNFCVVRVGVGMTRPEVTWGEPQNMPTDIELEPVTGKALQEFGRYQSIVYNLPKMVSLLVEPWYALIGDREQTLGLMRSIICQLTFSHGPDHVQMVVVSSDLEQWDWVKWLPHFGDPRRQDAAGNARMVYSSVREFATEQAELFAGRGSFTPRHASSSAQTPTPHHLIVADVVDPEWEYVISVEGIDGVTFFDLTGSSMWTVVPKRTLRFDEKGVIDALPRDRDTWMVIDDKPWFFALADQLSFAEAEEFAQKLAHWRPAEAYEEIGQRVAHIGARDILSYYGIGDPSAIDFDALWNSRTDAMGKSRLRVPFGNRSDNGELLFLDMKSLDEGGDGPHGVMSGTTGSGKSTLVRTVIESLMLAHPPEELQFVLADLKGGSAVKPFAGVPHVSRIITDLEEDQVLMERFLDALWGEIARRKAVCDNAGVDDAKEYNSVRTRMRARGQDMPALPMLVVVIDEFYEWFRIVPTAVDVLDSIGRQGRAYWIHLMMASQTIESRAEKLMENMGYRLVLKARTAGAAQAAGVPNAVNLPAQAGLGYFRKSLEDVIRFQAEFLWRDYFRGVTLDGEEQPVLVHNIDYVRPQLFTNLFTPLEVSVGGPEVDAEAVFANAQEFDEEIAEEEAEGGVRTPKIGTVIIDQLRRIDFEPYRLWQPPLTQPVAIDDLVNRFLGHPWQKDYGSARNLVFPIGVIDRPFKHDQPAWTVDTSGPGSNVLVLGAGGSGKTTALQTIICSAALTHTPEQVQFYCLGYSGTALTTVAHLPHVGEVAGPTDPYGVRRTVAELLALVRDRKRSFLEHGIASMEVFRRRKFGGELGPVPNDGFGDVYLVIDNYRALVEENEVLIEQVNQIINQGPSFGVHVVVTADRESELRPQVRSGFGSRVELRLAAVEDAKLVRSRFAKDVPVQSGRGMVAVNYVRLDSDPQAGLHTLVARPALANTPANVFESDSVVAPVSRLTSAQAPPVRRLPARFGMEQVRERAVRDTRQGVGVGGIAWAISELDLQPVYLNFAENAHLMITGRRECGRTTVLATIMSEIGRLYAPGGTSAPPTSERSAQVWLIDPRRQLLTMLGSNYMEKFAYNLDGVSAMVGELAALLASREPPPDLSAEELLSRSWWSGPEIFLIIDDIQQLPPSFDSPLQKVVPWVTRAGDVGLHVIATRTFGGWSSAGSDPMLRALHQANAPLLVMDADPDEGFIRGKMKGGPLPRGRGLLMAEDTGVLVQVAETDMR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccC5 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

79 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccC5

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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