eccB5
mL1544c
ESX CONSERVED COMPONENT ECCB5. POSSIBLE MEMBRANE PROTEIN.
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1866375 – 1867895
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1544c_eccB5_dna
TCTAACGTGGCCGAAGAGAGCAGCGGGCGGCGGGGGTCGGAGTACGGCCTTGGTTTGTCAACACGGACTCAGGTGACGGGTTATCAGTTCCTTGCCCGCCGAACCGCAATGGCGTTGACGCGGTGGCGCGTCCGCATGGAGGTCGAACCAGGTCGCCGCCAGACGTTAGCGGTGGTGGCGTCGGTTTCCGCGGCATTGTTGGGTTGCCTGGGAGCGCTGCTGTGGTCGTTTATAAGCCCATCCGGCCAGCTGAATGAGTCGCCTATCATCATTGACCGTGACTCTGGCGCGCTGTACGTCCGGGTAGGGGATAGGTTGTACCCCGCTTTGAATCTGGCGTCCGCACGGCTGATCACCGGACGACCGGACAATCCGCACGCGGTTCGGTCCAGCCAAATCGCCACGCTACCGCACGGACCGCTGGTGGGCATCCCAGGCGCACCGTCGGAGTTATCACCTGAAACTCCACAGACATCATCATGGCTGGTGTGCGATACGGTGGCCACCTCGACCGGGATTGGGTCGTCGTCTGGGGTGACGGTCACAGTGATCGACGGATCCCCAGACCTGTCTGGCCACCGTCGGGTGCTGACCGGCTCGGATGCGGTAGTGCTGCACTACGGTGGGGATGCGTGGGTCATCCGGCAGGGACGCCGGTCCCGTATCGACGCCATGAACCGGTCGGTGCTGTTGCCATTGGGCTTGACCCCAGAGCAAGTCAGTCAAGCGCGCCCGATGAGTCGTGCGTTGTTCGATGCTTTGCCGGTGGGTCCCGACTTGGTGGTGCCAGACGTACCAAACGAGGGCAATCCGGCCTCTTTTCCGGGTGCTCCGGGACCGGTGGGTACGGTGATTGTCACACCACAGATCAGTGGTCCGCAACAGTATTCGCTGGTGTTGGCTGACGGCGTGGAGACGGTCTCCCCACTGGTGGCTCAGATCATGCAAAACGCAGGTAAACCAGGAAACACCAAACTAATCACCGTAGCACCGTCTGTGTTGGTAAAGATGCCGGTGGTCAATAAGCTGGATTTGTCTGTTTACCCCGACACCCCGTTGCAAGTGGTGGACCTCCGAGAGAATCCGTCGACCTGTTGGTGGTGGGAACGGACCGCTGGTGAGAGCCGGTCTCGTATCCAGGTGATAACTGGGTCAACCATTCCAATTAACTCAGCCGATGTGAAGAAGGTGGTGTCGTTGGTGAAGGCGGACACAACTGGACGCGAAGCTGATCAAGTCTACTTCGGTTCTAACTATGCCAACTTCGTTGCAGTCACCGGCAACAATCCAGCGGCACAAACAACGGAATCACTGTGGTGGGTCACGCGGACGGGAGCTCGGTTTGGAGTGGAAGACACCAAGGACGTTCGTGACGCATTAGGTTTGAACGGCACGCCCAATTTGGCGCCCTGGGTAGCCTTGCGGCTATTGTCGCAAGGCCCGACTCTGTCCCGAGCAGATGCATTGATGGAGCACGACACGCTACCTATGGACATGACCCCTGCCGAGTTGGTGGTACCT

Protein Sequence 

>ML1544c_EccB5_protein
SNVAEESSGRRGSEYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEVEPGRRQTLAVVASVSAALLGCLGALLWSFISPSGQLNESPIIIDRDSGALYVRVGDRLYPALNLASARLITGRPDNPHAVRSSQIATLPHGPLVGIPGAPSELSPETPQTSSWLVCDTVATSTGIGSSSGVTVTVIDGSPDLSGHRRVLTGSDAVVLHYGGDAWVIRQGRRSRIDAMNRSVLLPLGLTPEQVSQARPMSRALFDALPVGPDLVVPDVPNEGNPASFPGAPGPVGTVIVTPQISGPQQYSLVLADGVETVSPLVAQIMQNAGKPGNTKLITVAPSVLVKMPVVNKLDLSVYPDTPLQVVDLRENPSTCWWWERTAGESRSRIQVITGSTIPINSADVKKVVSLVKADTTGREADQVYFGSNYANFVAVTGNNPAAQTTESLWWVTRTGARFGVEDTKDVRDALGLNGTPNLAPWVALRLLSQGPTLSRADALMEHDTLPMDMTPAELVVP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EccB5 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

4 proteins show strong predicted evidence for PPIs

19 show intermediate predicted evidence for PPIs

76 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EccB5

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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