infB
mL1556c
PROBABLE TRANSLATION INITIATION FACTOR IF-2 INFB
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1880183 – 1882957
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1556c_infB_dna
GATGTAGTGGCAGGTAAGGCCCGTGTACACGAGTTGGCTAAGGAACTCGGTGTTACAAGCAAAGAAGTCCTCGCCCGGCTAAATGAGCAGGGCGAATTCGTCAAGTCTGCGTCGTCGACGGTCGAAGCACCGGTCGCTCGCCGGCTCCGTGAATCGTTCGGTGGCATCAAGCCGGCCGCGGATAAGGGTGCTGAGCAGGTAGCCACAAAAGCCCAGGCCAAACGCCTCGGCGAATCGCTCGACCAAACCCTTGACCGGGCTCTCGACAAGGCGGTCGCAGGCAACGGTGCGACGACTGCTGCGCCGGTACAGGTCGATCATTCCGCTGCAGTGGTGCCTATTGTGGCTGGCGAGGGTCCTTCAACCGCGCATCGTGAGGAACTGGCGCCGCCCGCAGGACAGCCTTCGGAGCAGCCGGGAGTGCCGCTCCCTGGCCAACAGGGCACTCCAGCGGCGCCCCATCCGGGCCATCCGGGGATGCCGACCGGCCCGCACCCCGGGCCGGCACCTAAGCCAGGGGGTCGTCCCCCGCGCGTTGGTAACAACCCGTTTTCGTCGGCGCAATCTGTAGCCCGGCCCATCCCTCGTCCGCCGGCACCCCGCCCGAGCGCTTCGCCAAGCAGCATGTCGCCGCGTCCCGGAGGTGCAGTTGGGGGAGGGGGACCCCGTCCACCACGTACTGGCGTACCCCGACCCGGTGGGGGTCGGCCGGGCGCTCCCGTCGGCGGTCGCTCCGATGCGGGTGGCGGTAACTACCGTGGCGGGGGTGTCGGAGCCCTGCCGGGTGGCGGCTCGGGAGGTTTTCGTGGCCGTCCCGGTGGTGGCGGCCACGGTGGTGGCGGCCGGCCCGGACAGCGCGGCGGTGCGGCCGGTGCATTTGGCCGTCCTGGCGGTGCACCCCGGCGCGGTCGTAAGTCCAAGCGGCAGAAGCGCCAGGAATACGACTCTATGCAAGCTCCTGTCGTTGGCGGCGTGCGGTTACCGCATGGCAACGGCGAGACGATTCGATTGGCGCGCGGAGCATCCCTCTCGGACTTCGCCGAGAAAATTGACGCCAATCCGGCTGCATTGGTGCAGGCGCTGTTTAACCTCGGGGAGATGGTGACGGCAACCCAGTCGGTCGGTGACGAGACACTCGAGTTGCTGGGTAGCGAGATGAATTACAACGTCCAGGTAGTCAGCCCCGAGGACGAAGACCGTGAGTTGCTAGAACCCTTCGACCTCACTTACGGTGAGGACCAAGGAGACGAAGACGAGCTGCAGGTCCGTCCGCCGGTCGTGACCGTAATGGGCCACGTCGACCACGGCAAGACCCGCCTGCTGGATACTATACGAAAGGCCAACGTCCGCGAGGCCGAGGCTGGCGGCATCACCCAGCACATCGGTGCCTACCAGGTCGGAGTCGACCTCGACGGCAGCGAGCGGTTGATCACCTTCATCGACACCCCGGGCCACGAGGCGTTCACCGCCATGCGTGCTCGGGGCGCCAAAGCCACCGACATCGCCATCCTGGTGGTTGCCGCCGACGACGGTGTGATGCCGCAGACGGTGGAGGCCATCAACCATGCGCAGGCCGCTGACGTGCCGATCGTGGTGGCGGTTAACAAGATCGACAAGGAAGGTGCTGACCCGGCTAAAATCCGTGGCCAGCTCACCGAATATGGTTTGGTAGCAGAGGATTTCGGTGGCGACACCATGTTCATCGACATCTCGGCAAAGGTGGGCACCAACATCGAGGCCCTGCTCGAGGCGGTGCTGCTGACCGCCGATGCCGCTCTGGACTTGCGGGCTAACTCCGGCATGGAGGCCCAGGGTGTGGCGATCGAGGCGCACCTGGACCGCGGTCGAGGTCCGGTCGCCACGGTGTTGGTACAGCGCGGTACGCTGCGCATCGGCGACTCGGTCGTCGCCGGCGACGCGTATGGCCGTGTCCGCCGCATGGTCGACGAACACGGAGTGGACATCGAGGCGGCGCTACCGTCGAGTCCGGTGCAGGTCATCGGGTTCACGTCGGTGCCCGGCGCTGGTGACAACTTCCTGGTCGTTGACGAGGATCGCATCGCCCGCCAGATCGCCGATCGGCGCAGCGCCCGTAAGCGCAACGCCTTGGCGGCGCGTTCGCGCAAGCGAATCAGCCTGGAGGACCTGGATTCGGCGCTGAAGGAAACCAGCCAGCTGAACCTGATCCTCAAGGGCGACAACGCCGGTACGGTCGAGGCGTTGGAAGAGGCGCTGATGGGCATACAGGTCGACGACGAAGTCGCTTTGCGCGTTATTGATCGGGGCGTCGGTGGCATCACCGAGACTAATGTCAATCTTGCGTCGGCCTCGGATGCGATCATCATTGGCTTCAACGTGCGCGCTGAAGGTAAAGCCACCGAGTTGGCAAGCCGCGAGGGCGTGGAGATCCGCTACTACTTGGTCATTTACCAGGCGATCGATGATATCGAAAAGGCCCTGCGTGGCATGCTCAAACCGATTTACGAAGAGAATCAGCTGGGGCGTGCCGAGATCCGGGCGCTGTTCCGTTCCTCAAAGGTAGGCATCATTGCTGGCTGCATAATCAGTTCGGGTGTGGTGCGGCGCAACGCGAAGGTCCGGCTGTTGCGTGACAACATCGTGGTCACCGACAACCTCACGGTGACCTCGCTGCGTCGGGAAAAAGATGACGTGACCGAGGTACGCGAGGGCTTCGAGTGCGGTATGACGTTGGGTTACTCGGATATCAAGGAGGGTGATGTTATTGAGTCCTACGAGTTGGTAGAGAAACAACGT

Protein Sequence 

>ML1556c_InfB_protein
DVVAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding InfB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

99 show weak predicted evidence for PPIs

View all pooled AlphaFold results for InfB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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