efpA
mL1562c
POSSIBLE INTEGRAL MEMBRANE EFFLUX PROTEIN EFPA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1886300 – 1887904
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1562c_efpA_dna
CCGGCTATGGTGACTCTTTACGACCATGAGCGGGCAGTCCACAACTGGACAGCTGCACGATCGGATCGTCCGGCCCCGTCGCGACTGACGCAGCAGGTGGAGCCCGCCTCAGAACGCACAAGCAAGTACCCGACGTTGCTGCCTTCTGGTCGTTTCCCTTCTGGTCGTTTCATTGCAGCGGTCATCGTGATCGGTGGCATGCAGCTATTGGCGACCATGGACAGCACCGTCGCCATCGTCGCGCTTCCCAAGATTCAAAACGAGCTGAGCCTGTCCGACGCCGGCCGTAGTTGGGGGATTACTGCCTACGTGCTGACATTCGGCGGGCTGATGTTGCTCGGTGGCCGCCTCGGCGACACCATCGGGCGCAAGCGCACGTTCATCGTCGGCGTCGCGCTGTTTACTATTTCCTCGGTGCTTTGCGCTGTGGCCTGGGACGAAGTGACCTTGGTCATTGCTCGACTATTGCAGGGCATCGGGTCGGCTATCGCATCACCGACCGGTCTCGCACTGGTTGCAACCACCTTCTCTAAGGGCTCAGCGCGCAATACCGCTACGGCGGTGTTCGCCGCGATGACGGCAATCGGCTCGGTGATGGGCCTCGTGGTCGGCGGGGCGCTTACCGAGGTGTCGTGGCGACTGGCGTTTTTAGTGAACGTGCCGATTGGGTTGGTGATGATCTACCTGGCCCGCACCGCTTTGCATGAGACCCACAAGGAGCGGATGAAGCTGGACGCGGCTGGGGCCATTCTGGCCACGCTGGCTTGCACCGCGGCCGTTTTCGCCTTCTCGATGGGACCGGAGAAGGGTTGGATTTCGCTGACCACGATCGGTTCGGGCTTGGTGGCATTGGTAGCCGCTATCGCATTTGCCGTCGTGGAACGTACTGCTGAAAATCCTGTCGTACCGTTTGACCTGTTCCGGGACCGTAATCGGCTGGTCACCTTCATCGCGATTTTCCTGGCCGGTGGCGTCATTTTCAGCTTGACTGTATCCATCGGCCTATACATACAGGACATCTTGGGCTACAGCGCGCTACGCGCTGGCATCGGCTTTATCCCGTTCGTCATCGCGATGGGAATCGGCCTGGGCGTGTCTTCACAGTTGGTGTCTCGGTTTTCGCCACGGGTATTGACGATAGGTGGTGGATGGCTGCTCATGGTCGCTATGCTGTACGGTTGGGCGTTCATGAACCGCGGCGTTCCCTATTTTCCCAACCTGTTAGCACCCATCGTCGTTGGTGGAATCGGCATCGGCATGGCCGTCGTCCCGCTGACGTTGTCTGCTATCGCCGGGGTAGGTTTCGATCGGATCGGCCCGGTGTCCGCGATTGCGCTAATGCTGCAGAGCCTCGGCGGGCCACTCGTGCTGGCTGTCATCCAAGCGGTCATCACCTCGCGCACGCTGTACCTGGGCGGTACCACCGGCCCAGTGAAGTTTATGAACGACGCGCAGTTGCGTGCACTTGATCACGGCTACACCTACGGCCTGCTGTGGGTGGCCGGAGCGGTCGTCATCGTCGGCGTGGCGGCGCTGTTCATCGGGTACACCCCCGAGCAGGTGGCCTACGCGCAGGAGGTCAAGGAAGCGGTCGACGCCGGCGAA

Protein Sequence 

>ML1562c_EfpA_protein
PAMVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRFPSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITAYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVIARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLVVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRAGIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGE

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding EfpA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

77 show weak predicted evidence for PPIs

View all pooled AlphaFold results for EfpA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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