dxr
mL1583c
PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1908221 – 1909441
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1583c_dxr_dna
CTTGGGGTGAACAATCCGATCGAGGGGCACGCTGGCGGCCGCCTCCGCGTGCTGGTGTTGGGAAGTACTGGCTCAATTGGCACCCAGGCGCTGGAAGTTATCGCCGCCAATCCGGACCGTTTCGAGGTAGTCGGGCTGGCCGCCGGGGGCGCGCAGCTGGACACGCTGCTGAGGCAGCGCGCCGCGACCGGCGTCACCAATATCGCCATCGCTGACGATCGCGCGGCTCAGCTGGCCGGCGACATCCCTTACCACGGGACCGATGCGGTCACCCGGCTGGTTGAGGAGACTGAGGCTGACGTTGTCCTCAATGCGCTGGTCGGGGCATTGGGTCTGCGACCCACACTGGCTGCACTGCACACGGGCGCGCGATTGGCGTTGGCCAACAAGGAATCGCTGGTAGCTGGCGGTTCGCTGGTGTTGGCCGCGGCGCAGCCAGGCCAGATCGTGCCCGTAGACTCGGAACACTCCGCGCTGGCGCAATGCCTGCGCGGTGGTACCCCCGACGAAGTTGCTAAGTTAGTGCTAACCGCCTCCGGCGGGCCGTTTCGTGGCTGGAACGCCGGCGACTTGGAGCGCGTTACACCCGAGCAGGCGGGCGTCCATCCGACTTGGTCAATGGGGACGATGAACACGCTGAACTCAGCGTCTCTGGTTAACAAGGGGCTCGAGCTCATCGAAGCCAACCTGTTGTTCGGCATTCCCTACGACCGCATTGAGGTGGTTGTGCACCCTCAGTCAATTGTTCATTCGATGGTGACATTCATCGACGGCTCGACGATCGCCCAAGCCAGCCCTCCGGACATGAAGCTACCTATTTCTTTGGCGTTGGGCTGGCCACAGCGGGTGGGTGGCGCTGCTCGAGCCTGTGCTTTCACTACCGCATCTACCTGGGAATTCGAGCCGCTGGACATCGATGTTTTTCCCGCAGTCGAGCTGGCCCGGCACGCTGGACAGATCGGCGGCTGTATGACCGCCATTTACGATGCTGCTAATGAGGAGGCTGCAGAGGCCTTCCTCCAAGGTCGGATCGGCTTCCCCGCCATCGTCGCAACAATCGCGGATGTGTTGCAGCGTGCCGACCAATGGGCTCCCCAATGGGGTGAGGGACCCGCTACTGTGGATGATGTACTCGACGCGCAGCGCTGGGCCCGTGAGCGAGCGTTGTGTGCGGTAGCAACAGCGAGTTCTGGAAAGGTCTCTGACATGGTCTTAGAAAGG

Protein Sequence 

>ML1583c_Dxr_protein
LGVNNPIEGHAGGRLRVLVLGSTGSIGTQALEVIAANPDRFEVVGLAAGGAQLDTLLRQRAATGVTNIAIADDRAAQLAGDIPYHGTDAVTRLVEETEADVVLNALVGALGLRPTLAALHTGARLALANKESLVAGGSLVLAAAQPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWNAGDLERVTPEQAGVHPTWSMGTMNTLNSASLVNKGLELIEANLLFGIPYDRIEVVVHPQSIVHSMVTFIDGSTIAQASPPDMKLPISLALGWPQRVGGAARACAFTTASTWEFEPLDIDVFPAVELARHAGQIGGCMTAIYDAANEEAAEAFLQGRIGFPAIVATIADVLQRADQWAPQWGEGPATVDDVLDAQRWARERALCAVATASSGKVSDMVLER

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Dxr with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

14 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Dxr

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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