lepB
mL1612c
PROBABLE SIGNAL PEPTIDASE I LEPB (SPASE I) (LEADER PEPTIDASE I).
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1936170 – 1937039
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1612c_lepB_dna
GATCATCGTGACCGAAACCACGGACTCCGTACCTGAACCTCCGTCCGACGCTGACCAGTTGCAGCCGAAGGTGTCTATCTGTGGTCTTGATATGCCCGCTGAAGTATCTGAGACTGCCGCGGAAGCCGCAATAGGCGTGTCGGAGCCCAAGAAGCGTTCGGCGTTGTGGGAATTCGCGATTTTGGCGGTGATCGCTATAGGCTTGTACTACGTCATGTTGACGTTCGTGGCACGCCCCTACCTGATTCCGTCGGAATCCATGGAGCCCACGCTGCACGGATGCTCGGGCTGTGTGGGCGACCGCATCATGGTGGATAAGATCACTTATCGCTTCAGCTCACCACAACCTGGTGACGTCATCGTCTTCAAGGGCCCGCCGTCGTGGAACACGATGTACAAATCTATCCGGTCAAACAACATCGTGCTGCGCTCGGTGCAAAACGCGTTGTCGTTCGTCGGTTTCGTGCCTCCCGACGAGAACGACTTGGTCAAGCGCGTTATCGCGGTCGGAGGACAGACGGTGCAGTGCCGGTCCGACACGGGCTTGACGGTCAATGGGAAGCCACTCAAAGAGCCGTATCTCAGGCCGGTCACCATGAATGCCGACCTGTCATTCTCCCCGTGCCTGGGTAGCGAGTTCGGTCCAGTCACGGTCCCGCAGGGACGCCTGTGGGTTATGGGTGATAACCGGATACACTCCGCGGACTCGCGTTACCACTGCAACTCCACCGACGTGGTGAATGGGCTTTCGTGCACCGGTGATCCGAATTCGGGGACTGTGCCGGTGTCCAATGTCATCGGTAAGGCCAGGGTCGTCGTGTGGCCGCCGTCACGATGGGGTGGTGTGGGTTCGGTGAATTCCCAGCAGGG

Protein Sequence 

>ML1612c_LepB_protein
DHRDRNHGLRT_TSVRR_PVAAEGVYLWS_YAR_SI_DCRGSRNRRVGAQEAFGVVGIRDFGGDRYRLVLRHVDVRGTPLPDSVGIHGAHAARMLGLCGRPHHGG_DHLSLQLTTTW_RHRLQGPAVVEHDVQIYPVKQHRAALGAKRVVVRRFRASRRERLGQARYRGRRTDGAVPVRHGLDGQWEATQRAVSQAGHHECRPVILPVPG_RVRSSHGPAGTPVGYG__PDTLRGLALPLQLHRRGEWAFVHR_SEFGDCAGVQCHR_GQGRRVAAVTMGWCGFGEFPAG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LepB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

73 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LepB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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