htpG
mL1623
PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1945512 – 1947482
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1623_htpG_dna
CACAAGTCGAACAGCTGGAGTTTCAGGCGGAGGCACGCCAACTTCTGGACTTGATGGTCCATTCGGTCTACTCCAATAAAGATGCATTTTTGCGGGAGCTGATCTCGAATGCCTCCGACGCGCTGGACAAGCTTCGGCTTGAAGCGTTTCGGAACAAAGACTTGGACCCACGTACAGTTGACACCTCCGATCTGCACATCGAGATCGAAGTGGACAAAAATACACGCATTTTAACCGTCCGTGACAACGGCATAGGTATGACACGCGCGGAGGTGGTGGACTTGATCGGTACACTGGCCAAGTCAGGGACCGCCAAGCTGCGTCAGAAATTGCATGCGGCCAAAAATCTGAAAGACACCGCCGCCTCTGAAGGACTGATCGGTCAGTTCGGTATCGGTTTTTACTCGAGTTTCATGGTAGCCAACAAGGTCGAACTTCTCACCCGTAAAGCCGGTGAGACTGCGGCCACGAGATGGTCATCGGACGGTGAGGCCACCTACACCATCGAATCCGTCGACGAAGCTCCGCAGGGAACATCAGTGACGTTGCACCTCAAACCCGAAGACTTCGAGGACGAGTTGCACGACTACACCTCGGAATGGAAGATCAGGGAGCTGGTCAAGAAGTACTCCGACTTCATCGCCTGGCCTATCCGGATGGAAGTTGAGCGACGCGCGCCGGCCACCTCGGACGGAGAAGGGGCGGATGGTGAAGAGCAAGTCACCATCGAAACCCAGACCATCAACTCAATGAAGGCGTTGTGGACTAAGTCAAAAGACGAGGTCTCAGAGGACGAATACAAGGAGTTCTACAAGCACATCGCCCACGCCTGGGATGACCCACTCGAGGTGATCGCGATGAAGGCCGAGGGCACCTTCGAGTACCAGGCGCTGCTTTTTATTCCTTCGCACGCTCCGTTCGACCTGTTTAACTCCGACGCCAAAATCGGCATGCAGCTGTATGTCAAACGCGTCTTCATCATGTCCGACTGCGATCAGCTCATGCCGATGTACTTGCGTTTCGTCAAAGGGGTTGTAGACGCAGAGGACATGTCGCTCAATGTTTCTCGAGAAATCCTGCAACAGAATCGGCAAATCAATGCGATCCGTCGCCGGCTGACCAAGAAGGTCCTTTCAGCAATCAAAGATCTGCAGGCCGAACGACCACAGGACTACCGCACGTTCTGGACACAGTTCGGCAAGGTCCTCAAAGAGGGACTCATGTCGGACTCCGACAATCGAGACACACTGCTTCACATTTCCTCGTTCGCCTCGACACACAGCGACGAAGAACCCACCACCCTGGCCCAATACGTAGAACGCATGAAAGACGGCCAAGACCAAATCTTCTACGCCACAGGAGAGTCGCGTCAGCAAGTCATGAATTCGCCACATCTCGAAGCATTCAAGGCCAAGGGCTATGAGGTGCTGTTGCTGACCGACCCGGTCGACGAGGTTTGGGTAGGAATGGCACCCGAGTTCGACGGCAAGCCGTTGAAATCGGTAGCTAGGGGCGAGGTGGACCTCGAATCCGAAGAGGAAAAGACAGCGCACGAAGCTGAACGCAAGGAGCAGGAGCAGAATTTTGCTGGGCTGGTGAACTGGTTGAAAGAGACCTTGAGTGATCACGTCAAAGAGGTACGGTTATCCACACGCCTCACCGAGTCGCCAGCCTGCCTGATCACTGATGCCTTCGGTATTACGCCGGCGCTGGCGCGCATCTACCGGGCTTCCGGGCAGGACGTTCCGTTCGGAAAACGGATTTTGGAACTCAATCCAAATCATCCACTGATCACTGGCCTGCAACAGGCACACGAGAACGGCGGTGATGATACTCACCTGCGTCAACTCTCCGAAACTGCCGAATTGTTGTACGGTACCGCCCTTCTCGCTGAAGGCGGAGCACTAGAGAATCCGGCAAAGTTCGCCGGATTGCTCGCGGATCTTCTGTCCCGGTCGATGTAGGAAACGC

Protein Sequence 

>ML1623_HtpG_protein
HKSNSWSFRRRHANFWT_WSIRSTPIKMHFCGS_SRMPPTRWTSFGLKRFGTKTWTHVQLTPPICTSRSKWTKIHAF_PSVTTA_V_HARRWWT_SVHWPSQGPPSCVRNCMRPKI_KTPPPLKD_SVSSVSVFTRVSW_PTRSNFSPVKPVRLRPRDGHRTVRPPTPSNPSTKLRREHQ_RCTSNPKTSRTSCTTTPRNGRSGSWSRSTPTSSPGLSGWKLSDARRPPRTEKGRMVKSKSPSKPRPSTQ_RRCGLSQKTRSQRTNTRSSTSTSPTPGMTHSR_SR_RPRAPSSTRRCFLFLRTLRSTCLTPTPKSACSCMSNASSSCPTAISSCRCTCVSSKGL_TQRTCRSMFLEKSCNRIGKSMRSVAG_PRRSFQQSKICRPNDHRTTARSGHSSARSSKRDSCRTPTIETHCFTFPRSPRHTATKNPPPWPNT_NA_KTAKTKSSTPQESRVSKS_IRHISKHSRPRAMRCCC_PTRSTRFG_EWHPSSTASR_NR_LGARWTSNPKRKRQRTKLNARSRSRILLGW_TG_KRP_VITSKRYGYPHASPSRQPA_SLMPSVLRRRWRASTGLPGRTFRSENGFWNSIQIIH_SLACNRHTRTAVMILTCVNSPKLPNCCTVPPFSLKAEH_RIRQSSPDCSRIFCPGRCRKR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding HtpG with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

24 show weak predicted evidence for PPIs

View all pooled AlphaFold results for HtpG

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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