smc
mL1629c
PROBABLE CHROMOSOME PARTITION PROTEIN SMC
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1954861 – 1958472
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1629c_smc_dna
GCTGGTCGTGTACCTCAAGAGTCTGACGTTGAAGGGCTTTAAGTCCTTCGCGTCGCCGACGACTTTACGTTTTGAGCCGGGCATTACCGCTGTCGTTGGACCTAACGGCTCCGGTAAGTCCAACGTCGTCGATGCTCTGGCGTGGGTAATGGGGGAGCAGGGAGCCAAGACGCTGCGTGGGAGTAAAATGGAAGATGTCATTTTCGCCGGCACGTTGTCGCGCGCTCCGTTGGGTCGCGCAGAAGTCACTTTGATCATCGACAACTCCGACAACGTGCTGCCGATCGAGTACTCCGAGGTGTCGATCACGCGGCGGATGTTTCGCGACGGTGCTAGTGAATACGAAATTAACGGCAGTAGTTGCCGTTTGATGGATGTCCAGGAATTGCTGAGCGACTCCGGCATTGGCCGCGAGATGCATGTGATTGTCGGGCAGGGTAAGCTCGATCAGATCCTGCAGTCACGGCCCGAGGACCGTCGGACCTTCATCGAAGAAGCCGCAGGCATACTTAAGTATCGTAGGCGCAAGGAAAAGGCTTTGCGAAAGCTCGATGCTATGTCGGCGAATCTGGCCCGGCTCACCGATTTGACTACGGAATTACGACGTCAGCTCAAGCCGTTGAGCCGTCAAGCCGAAGTGGCCCGACGGGCCGCGACTATTCAGGCCGATTTACGCGACGCTCGGTTGCGATTGGCCGCAGATGATCTGGTAAGTCGACAAGGGCAGCGAGATGCGATCGTCGAGGCTGAGACGATGATGCGCCGTGATCATGATGAGGCGGCTGCTCGGCTGGCGGTAGCGTCCGAAGAGCTGGCGGCGCATGAAGCTGCGCTTACCGAGCTTTCGGGACGGGCTGAGTCGGTCCAGCAGATCTGGTTCGGGTTGTCCACCCTGGTCGAGCGGGTAAGTGCAACGATTCGGATCGCCGGCGAACGCGCGTACCATCTTGATGTCGATCCAGCCACACCGAGCGACACCGACCCCGACGTGTTGGAGGCCGAGGCCCAGCAGATGGAGGTCGCCGAGCAGCAGCTGCTGGCGGAGCTGGCTGTAGCACGTACCCAATTGGAGGCCGCTCGTGCCGAATTGGCCGACCGCGAGCGCCACGCCGTTGAGGCCGACAAAGCGCATCTGGAGGCGGTCCGTGCGGAGGCGGATCGGCGCGAGGGGTTGGCGCTGCTGGCCGGCCAGGTGGAGACTATGCGGGCGCGTATCGAATCGATCGATGATAGCGTCGCGCGGTTGTCCGAGCGCATCGAGGAGGTTACTGCACGAACCCAGCAGATTCTCGCGGAGTTTGAAACCGTGCAGGGCCGCGTCGGTGAACTGGATCAGAGCGAGGTCCACCTTGACGAACAGCACGAACGGGCCGTGGCGGCATTGCGGTTCGCTAACGAACGCGTGGCTGAACTGCAGTCCGCTGAGCGAGACGCCGAACGCCAGGTGGTTTCGCTGCGAGCTCGTATTGACGCGCTGACGATGGGACTCGAGCGTAAGGACGGCGCGGCTTGGCTGGCACGCAATTACAGTGACACCGGGCTCTTAGGTTCGATCGCCAAGTTGGTGAAGGTGCGCCCCGGCTACGAGGCAGCGCTGGCTGCAGTGCTCGGGCCCGCGGCAGATGCGCTGGCCGTCGATAGTTTGGGCGCGGCTCGTAGCGCACTCACCGCGCTTAAGGAAGCCGACGCAGGCCGCGCGACCCTCGTCTTGGCTGACTGGCTGGCGGATGCGGGACCGGCCTGCGTTACTGGGCTGCCCGATGGGGCTCAACGTGCGCTCGATTTGATTGAGGCACCGCCGTGGCTGCAGGGCGCGTTGATCGCTATGCTGTACGGTGTCGTGGTGGTCAACTACCTCGCCGAAGCGTTGGGCGTGGTCGATATCTGTCCGCAGTTGCGGGTGGTCACCGTTGATGGTGATCTGGTGGGCGCCGGCTGGGTGAGCGGTGGTTCTGGCCGCAGACTGTCGACACTGGAGGTCACTTCGGAGATCGATAAGGCTGGTGCCGAGCTAGCCGCTGCCGAGGCACATATGGCGCAACTGAATGCCGCGTTGTCCGGTGCACTGTCCGAGCAGGTTGCCCATTCCGATGCCACTGAGCAGGCATTGGTCGCACTCAATGAATCCGACACTGCAATATTGTCAATGTATGACCAGCTAGGGCGGCTCGGGCAGGAGGTTCGCGCTGCCGAAGCAGAATGGGAAAGTCTGCTAGCCCAGCGCGAGGAATTAGAAGCCAGGCGTGTTTCGATTCTCGAAGAGGTTGTCGAACTAGAAACCCGGTTGCATAACGTCGAGCAGATCCAGCATGTGCATGCTCTCGATGAGAATTCTGCAGCGGCCCGGCAGCTGATTGTCGCCGCGGCCGAGGAGGCTCGTGGCGTCGAAGTGGAAGCCCTACTTGCGGTTCGGACTGCCGAAGAACGCGTCAATGCTGTGTGCGGGCGGGCGAATTCATTGCGTCGCGCGGCCGCTGCTGAGCGTGAGGTGCGGTTGCGGGACCAGCAAGCGCACGCCGCACGAATACGCGCGGCCGCGGTAGCTGCTGCGGTTACCGACTGCGGTCAGTTGCTGGCGTCCCGGTTGACCCAGGCTGTCGACCTGGCGGCGCGACACCGCGATGCACTGGCCACCGAGCGTCAGCAGCGATCGGTTGCAATAGCGGCTGTGCGCTACGAGGTAAACACTCTGAGGGTTCGGTTGGCCACCCTAACCGATTCGCTGCACCGCGACGAGGTGGCTAACGTTCAGGCGGCGCTGCGTATCGAGCAGCTCGAGCAGCTGGTGCTGGAGCAGTTCGGAATAGCGCCGGTGGATTTAATCGCTGAGTACGGTCCGCAGGTTGCGCTACTGCCGACCGAGCTCGAAATGGCTGAATTCCAACAGGCCCGGGAGCGTGGTGAACAGGTGACTTCGCCTGCTCCGATGCCGTACGACCGCGCTACCCAGGAGCGTCGGGCCAAACGTGCGGAGCGTGAACTAGCTGAGCTGGGCAGGGTCAATCCGCTGGCGCTGGAGGAGTTCGCTGCACTAGAGGAACGCTATAACTTCTTGTCTACCCAACTTGAGGATGTCAAGGGTGCCCGCAAGGATCTGCTCGACGTTGTCGCTGAAGTCGATGCTCGTATCCTGCAGGTGTTCAGCGACGCCTTTGTGGATGTGGAGCGTGAATTCCGCGGTGTCTTTACCTCACTGTTCCCCGGTGGCGAAGGTCGGCTAAGGTTGACCGATCCGGATGACATGCTCACCACTGGCATAGAAGTAGAGGCGCGTCCGTCCGGCAAGAAGGTTAGCCGGCTATCGTTGCTGTCCGGTGGCGAGAAGTCGCTGATTGCGGTGGCTATGTTGGTGGCGATTTTTAAAGCTCGCCCGTCACCGTTCTACATCATGGATGAGGTGGAGGCTGCGCTCGACGATGTCAATCTGTGTCGCTTAATTGGTGTGTTTGAGCAACTGCGTGGCCAGTCGCAGCTTATAATCATTACGCACCAGAAACCGACGATGGAAGTCGCTGACACACTGTACGGCGTGACCATGCAGGGCGATGGTATCACTGCGGTGATCTCACAGCGGATGCGCGGTCAGCAGGTAGAGTCGCTAGTAACCAGTTC

Protein Sequence 

>ML1629c_Smc_protein
AGRVPQESDVEGL_VLRVADDFTF_AGHYRCRWT_RLR_VQRRRCSGVGNGGAGSQDAAWE_NGRCHFRRHVVARSVGSRRSHFDHRQLRQRAADRVLRGVDHAADVSRRC__IRN_RQ_LPFDGCPGIAERLRHWPRDACDCRAG_ARSDPAVTARGPSDLHRRSRRHT_VS_AQGKGFAKARCYVGESGPAHRFDYGITTSAQAVEPSSRSGPTGRDYSGRFTRRSVAIGRR_SGKSTRAARCDRRG_DDDAP_S__GGCSAGGSVRRAGGA_SCAYRAFGTG_VGPADLVRVVHPGRAGKCNDSDRRRTRVPS_CRSSHTERHRPRRVGGRGPADGGRRAAAAGGAGCSTYPIGGRSCRIGRPRAPRR_GRQSASGGGPCGGGSARGVGAAGRPGGDYAGAYRIDR__RRAVVRAHRGGYCTNPADSRGV_NRAGPRR_TGSERGPP_RTARTGRGGIAVR_RTRG_TAVR_ARRRTPGGFAASSY_RADDGTRA_GRRGLAGTQLQ_HRALRFDRQVGEGAPRLRGSAGCSARARGRCAGRR_FGRGS_RTHRA_GSRRRPRDPRLG_LAGGCGTGLRYWAARWGSTCARFD_GTAVAAGRVDRYAVRCRGGQLPRRSVGRGRYLSAVAGGHR_W_SGGRRLGERWFWPQTVDTGGHFGDR_GWCRASRCRGTYGATECRVVRCTVRAGCPFRCH_AGIGRTQ_IRHCNIVNV_PARAARAGGSRCRSRMGKSASPARGIRSQACFDSRRGCRTRNPVA_RRADPACACSR_EFCSGPAADCRRGRGGSWRRSGSPTCGSDCRRTRQCCVRAGEFIASRGRC_A_GAVAGPASARRTNTRGRGSCCGYRLRSVAGVPVDPGCRPGGATPRCTGHRASAAIGCNSGCALRGKHSEGSVGHPNRFAAPRRGG_RSGGAAYRAARAAGAGAVRNSAGGFNR_VRSAGCATADRARNG_IPTGPGAW_TGDFACSDAVRPRYPGASGQTCGA_TS_AGQGQSAGAGGVRCTRGTL_LLVYPT_GCQGCPQGSARRCR_SRCSYPAGVQRRLCGCGA_IPRCLYLTVPRWRRSAKVDRSG_HAHHWHRSRGASVRQEG_PAIVAVRWREVADCGGYVGGDF_SSPVTVLHHG_GGGCARRCQSVSLNWCV_ATAWPVAAYNHYAPETDDGSR_HTVRRDHAGRWYHCGDLTADARSAGRVASNQF

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Smc with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

97 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Smc

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.