glnE
mL1630c
GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE GLNE (Glutamine-synthetase adenylyltransferase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1959892 – 1962906
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1630c_glnE_dna
GACTGGGGTGTGTTGCACTACCGTCGTGGTTGTGAGAAAGCCCGCGACAGAGCGCCTCAAGCGGCCCAGTGTCGGCCGGCTCGGGTTGTTTGACCCTCATGCCGCGGAGAATCTCGCGCTACTGGGCTGGTATGACTACGATTGCCGAGAACATGTGGACCTGTTGTGGTCGCTGTCGCGGGCACCCGACGCCGATGCTGTGCTGCGCCCCATGGTCCGGCTGTTCGAGAACCCGGCCACCGGATGGGATGAGCTCAATGCCGCTTTGCTCACCGATCGCGGTCTGCGTGGGCGGCTATTTGCCGTGCTGGGCTCGTCGTTGGCGTTAGGCGATCACTTGGTCGCCCATCCGCAGTCTTGGAAGCTGTTGCGGGGCAGGGTCAGCTTGCCGTCCCGTACCCAGCTGCACCAGGCTTTCGACGAGTGCGTGAGTAATTTTGGGGATGACCCTTTGGATGCGCCAGACTCGGTACTGCCTCGATTGCGCACGTTATACTGTGATCAGCTGCTGGTGTTGGCCGCGCTCGATCTGGCCGCAACGGTCGAAGACGAGCCGGTGCTGCCGTTTACCCTGGTCGCTGCCCAGCTGGCTGATATTGCGGACGCCGCGATGGCGACTGCACTACGTGTGGCCGAAAAAATTGTGTGTGGTGATCGCACGCCACCGCGGCTGGCGGTCATTGCTATGGGCAAATGGGGTGCCCGCGAACTGAACTACGTCAGCGACGTCGACATCATCTTTGTCGCTGAGCAAGCTGACCCGCTCAGCACTCGCGTGGCCAGTGAGATGATGCGGGTGGCTTCGGAGGCGTTCTTCCAGGTGGACGCCGGGTTGCGGCCGGAGGGCCGCAACGGTGAACTGGTACGTACGGTCGAGTCGCACATCGCCTACTACCAGCGCTGGGCGAAGACCTGGGAGTTTCAGGCGTTGCTGAAAGCCCGCTCGGCGGTTGGCGATGCGGAACTGGGTGAGCGTTACCTGGCCGCGTTGATGCCGATGGTCTGGGCCGCCTGCGAACGTGCGGATTTCGTGGCCGAGGTGCAGGCCATGCGGCGGCGCGTGGAGCAGCTGGTGCCTGCGGATGTCCGCGGCCGCGAGCTCAAACTCGGAAGTGGCGGCTTGCGAGATGTGGAGTTTGCCGTGCAGCTTCTGCAGTTGGTGCACGGCCGCAGCGACGAGTCGCTGCATGTGGTTTCCACGGTAGACGCGCTGGCGGCGTTGGGTGAGGGCGGCTATATCGGCCGTGAGGACGCTGCGAACTTGACCGCCTCCTATGAGTTCCTGCGACTGCTTGAGCACCGACTGCAGCTGCAGCGACTCAAGCGCACTCACCTGCTGCCCGAGGACGGCGATGAAGAGGCGGTGCGTTGGCTGGCCCGCGCGGCGCACATCCGTCCGGACGGCCGGCACGACGCTGCGGGGGTGCTGCGCGAGGAGCTCAAGAACCAGAACCTGCGGGTATCACAGCTGCATGCTAAGCTCTTTTATCAGCCGCTGTTGGAGTCGATCGGGCCGGCCAGCCTGGAGATTCGTCACGGCATGACATCGGAGGCAGCCGAGCGGCAGCTGGCCACACTGGGCTATGAGGGCTCGCAGACCGCGTTGAAACACATATCGGCGCTGGTCAACCAGAGTGGGCGGCGAGGGCGGGTGCAGTCGGTGTTGTTGCCCCGGTTGCTCAATTGGATGTCGTATGCGCCCGACCCTGACGGCGGGCTATTGGCTTATCGGCGCTTGTCCGAGGCGCTGTCGGCTGAGACCTGGTACCTGTCCACGTTGCGTGACAAGCCAGCAGTGGCCAGGCGGCTGATGCATGTGCTGGGTACCTCTGTGTATGTGCCAGATTTGTTGATGCGTGCGCCCGAAGTCATTCAGTCTTACGGAGACGGGCTAGCGGGCCCGAAGCTGCTGGAGGCTGAGCCAGCCATGGTGGCTCGCGCGCTGATCACTTCGGCGGGCCGCCACACTGACCCGATACGGGCCATAGACGCCGCGCGTAGTCTGCGGCGTCGTGAGTTGGCCCGGGTCGGGTCCGCGGACCTCCTGGGCTTGTTGGAAGTCACCGAAGTGTGTAAGGCACTGACGTCGGTGTGGGTGGCGGTGTTGCAGGCCGCTTTGGACGCAGTGATCCGGGCCTACCTGCCTGACGGTGACAAGGCGCCGGCGGCCATCGCGGTCATCGGCATGGGCCGGTTAGGCGGTGCTGAACTGGGATACGGTTCAGATGCCGACGTGATGTTTGTCTGCGAGCCGGCCATTGGGGTCGAGGATGCGCAGGCGTTGCGATGGTCGGGGATGATCGCTGAACGGGTTTGCAGACTGCTGAGGACACCCAGCGTTGACCCGCCGTTGGACGTTGATGCCAATCTACGTCCCGAGGGTCGCAACGGACCGCTGGTTCGTACCTTGGGTGCCTATGCCGCCTACTATGCGCAGTGGGCTCAGCCGTGGGAGATTCAGGCCTTACTCCGCGCACACGCGGTTGCCGGCGACGCGGATTTGGGCCAGCGGTTCCTGCTGATGGCCGATAAAATGCGCTATCCACCCGATGGTGTATCTGCCGAGGCGGTGCGCGAGATTCGTCGGATGAAGGCGCGCGTCGAGGCCGAGCGTTTACCGCGCGGTGCCGACCCCCACACGCACACTAAGCTGGGCCGCGGGGGATTAGCCGACATCGAATGGACTGTCCAGTTGATGCAGTTGCGGCATGCGCACGAGCTGCCGGCTCTGCACAAGACTTCGACGTTGGAATCCCTAGACGCCATAGCTGCTGCCAACCTGATCCCCGAAGCAGACGTGGACCTGCTGCGGCAGGCGTGGCTGACCGCTACTCGAGCCCGCAATGCGCTGGTGCTGGTCCGGGGTAAGACCACCGACCAGCTGCCAGGGCCTGGACGCCAGCTTAACGCGGTCGCCGTCGCCGCCGGCTGGCCAAGCGATGACGGCAGCGAATTCCTGGACAACTATCTGCGGGTGACGCGACGTGCAAAAACATTTGTGCGCAAGGTTTTTGG

Protein Sequence 

>ML1630c_GlnE_protein
DWGVLHYRRGCEKARDRAPQAAQCRPARVV_PSCRGESRATGLV_LRLPRTCGPVVVAVAGTRRRCCAAPHGPAVREPGHRMG_AQCRFAHRSRSAWAAICRAGLVVGVRRSLGRPSAVLEAVAGQGQLAVPYPAAPGFRRVRE_FWG_PFGCARLGTASIAHVIL_SAAGVGRARSGRNGRRRAGAAVYPGRCPAG_YCGRRDGDCTTCGRKNCVW_SHATAAGGHCYGQMGCPRTELRQRRRHHLCR_AS_PAQHSRGQ_DDAGGFGGVLPGGRRVAAGGPQR_TGTYGRVAHRLLPALGEDLGVSGVAESPLGGWRCGTG_ALPGRVDADGLGRLRTCGFRGRGAGHAAARGAAGACGCPRPRAQTRKWRLARCGVCRAASAVGARPQRRVAACGFHGRRAGGVG_GRLYRP_GRCELDRLL_VPATA_APTAAAATQAHSPAARGRR_RGGALAGPRGAHPSGRPARRCGGAARGAQEPEPAGITAAC_ALLSAAVGVDRAGQPGDSSRHDIGGSRAAAGHTGL_GLADRVETHIGAGQPEWAARAGAVGVVAPVAQLDVVCARP_RRAIGLSALVRGAVG_DLVPVHVA_QASSGQAADACAGYLCVCARFVDACARSHSVLRRRASGPEAAGG_ASHGGSRADHFGGPPH_PDTGHRRRA_SAAS_VGPGRVRGPPGLVGSHRSV_GTDVGVGGGVAGRFGRSDPGLPA_R_QGAGGHRGHRHGPVRRC_TGIRFRCRRDVCLRAGHWGRGCAGVAMVGDDR_TGLQTAEDTQR_PAVGR_CQSTSRGSQRTAGSYLGCLCRLLCAVGSAVGDSGLTPRTRGCRRRGFGPAVPADGR_NALSTRWCICRGGARDSSDEGARRGRAFTARCRPPHAH_AGPRGISRHRMDCPVDAVAACARAAGSAQDFDVGIPRRHSCCQPDPRSRRGPAAAGVADRYSSPQCAGAGPG_DHRPAARAWTPA_RGRRRRRLAKR_RQRIPGQLSAGDATCKNICAQGFW

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GlnE with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

81 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GlnE

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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