ML1632c
mL1632c
Probable exported protease
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1964380 – 1965915
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1632c_ML1632c_dna
TGCAACGATGGTAGCCATGCCGAGCCTGAGATCGTTGAGCTCGGCGCTGCTTTCGTTAGGGCTGTTGCTGCAACCGGCAATGACACCGCCGGTGGTTGGTGCCAGCCCAGAGCAGACTCCTAGCCCGGTGCCGGAGCAGAACTGGGGTAATTGCAGTGTGTTCCTGTCCGACACTAGCGACATCCCCTCGGCACGGTGTGCAACGGTGTCGGTGCCGGTCGACTACAACAATCCTGATGGGGTGCACGCCGAATTGGCGGTCATCCGCGCTCCAGCGACTGGCCAGCGGATCGGATCGCTGCTGTTCAATCCGGGAGGACCCGGGGCGTCCGCGGTTGACATGGTCGCCGAAATGATACCAGGGCTACAACGTACCGATATTGGCCGTCACTTCGACCTGGTGGGGTTCGACCCGCGAGGAGTCGGCCACTCAACCCCGGCGCTTCGGTGTCGCACTGACGTTGAGTTCGACGCGTACCGGACCGAACCGATGGTTGACTACAGCCCGGCCGGTGTGGCGCACATCGAGCAAGTCTACAAGCAGCTCGCTCAACAGTGTGTTGCCCGGGTCGGCACCGCATTTTTGGCGAACGTGGGAACTGCCTCGGCCGCGCGCGACATGGATATAGTTCGCCTGGCTCTGGGAGACGAGCAGATCAATTACCTCGGTTATAGCTACGGCACCGAATTGGGTACCGCCTATCTCGAGCGGTTCAGCGACCATGTGCGGGCGATGGTGCTTGACGGCGCTATTGACCCGAGTGTTAGCTCAATCCAGAAAGACATCCAGCAAATGGCCGGATTCCAGATCGCATTTACCGACTATGCCGCGGACTGCGCCCGCTCGGCGTCCTGTCCACTGGGCACTGACCCCAGCCAATGGGTCAACCGATACCATGCGCTGATCGACCCGTTGGTTACCAAGCCGGGTCGGACGTCGGATCCACGCGGCCTGGGCTACGCTGACGCGACCACCGGCACCATTAATGCGCTCTACACCCCGGTGCACTGGAAATACCTGACCAGTGGCTTGCTTGGGCTGCAGCGTGGCACCGACGCCGGTGACCTGCTATTGCTCGCCGACGACTACAACGGCCGGGACCGCAATGGGCACTACACCAACGACCAGGACGCGTTTAACGCGATCCGCTGCGTCGACGCGCCGGTGCCAACCGACTCGGCGAGCTGGGTATCGGCCGATCAGCAGATACGCCAGGCCGCTCCGTTCCTCAACTACGGGCAATTCACCGGCAACGCTCCCCGCGATATCTGTGCACTGTGGCCGGTGCCGGCGACATCGATGCCGCACCCCGCGCCGCCGGTCGCGCCGGGCAAGGTTGTCGTGGTCTCCACAACGCACGACCCGGCCACTCCATATCAGGCCGGGGTAGACCTGGCTCGCGAGCTGAGCAGCCCGCTGATCACCTACGACGGAACCCAGCACACCGCGGTGTTCAACGGCGACCAGTGTGTGGATAGCGCGGTGGTGCATTATTTCGTGGACGAGACGTTGCTACCGGCGTCCTTACAATGTCA

Protein Sequence 

>ML1632c_ML1632c_protein
CNDGSHAEPEIVELGAAFVRAVAATGNDTAGGWCQPRADS_PGAGAELG_LQCVPVRH_RHPLGTVCNGVGAGRLQQS_WGARRIGGHPRSSDWPADRIAAVQSGRTRGVRG_HGRRNDTRATTYRYWPSLRPGGVRPARSRPLNPGASVSH_R_VRRVPDRTDG_LQPGRCGAHRASLQAARSTVCCPGRHRIFGERGNCLGRARHGYSSPGSGRRADQLPRL_LRHRIGYRLSRAVQRPCAGDGA_RRY_PEC_LNPERHPANGRIPDRIYRLCRGLRPLGVLSTGH_PQPMGQPIPCADRPVGYQAGSDVGSTRPGLR_RDHRHH_CALHPGALEIPDQWLAWAAAWHRRR_PAIARRRLQRPGPQWALHQRPGRV_RDPLRRRAGANRLGELGIGRSADTPGRSVPQLRAIHRQRSPRYLCTVAGAGDIDAAPRAAGRAGQGCRGLHNARPGHSISGRGRPGSRAEQPADHLRRNPAHRGVQRRPVCG_RGGALFRGRDVATGVLTMS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML1632c with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

55 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML1632c

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.