kasA
mL1655
3-oxoacyl-[acyl-carrier-protein] synthase 1 KasA (BETA-KETOACYL-ACP SYNTHASE) (KAS I)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1994880 – 1996130
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1655_kasA_dna
TGCCTTCCACTGCTAATGGCGGTTTCCCCAGTGTTGTGGTGACCGCTGTCACAGCAACGACGTCAATCTCGCCGGACATCGAAAGCACGTGGAAGGGTCTGTTGGCCGGCGAGAGCGGCATCCACGTACTCGAAGACGAGTACATCACCAAGTGGGACCTGCCAGTCAAGATCGGCGGCCACCTCAAGGAGCCAGTCGATAGCCACATGAGCCGCCTGGACCTGCGGCGCATGTCGTACGTCCAGCGGATGAGCAAGCTGCTCAGCGGTCGACTATGGGAGTCCACCGGCAGCCCGGAGGTCGATCCCGACCGGTTCACCGTCGTGGTCGGCACCGGTCTGGGCGGCGCCGAGCGAATCGTGGAAAGCTACGACCTGATGAACGCGGGCGGACCCCGTAAGGTGTCCCCGCTCGCCGTTCAGATGATCATGCCCAACGGCGCCGCAGCGACCGTCGGGCTACAGCTTGGGGCATGCGCCGGGGTGATGACACCGGTGTCGGCCTGCTCGTCGGGCTCTGAGGCAATCGCACACGCCTGGCGCCAGATCATCATGGGAGATGCAGATGTCGCCGTCTGTGGCGGTGTCGAGGGCCCGATCGAGGCGCTGCCTATCGCGGCGTTCTCGATGATGCGAGCCATGTCGACCCGTAACGACGACCCCGAGGGGGCATCTCGGCCATTCGACAAAAATCGTGACGGGTTTGTGTTCGGCGAAGCCGGAGCCCTGATGCTCATCGAGACTGAGGAGCACGCCAAGGCTCGCGGCGCCAAGCCGCTGGCTCGGTTGCTTGGTGCAGGCATCACCTCGGACGCCTTTCATATGGTGGCACCCGCGGCCGACGGCGTGCGAGCAGGGCGGGCAATGACCCGGTCGCTGGAGCTGGCGGGTTTGTCGGCGAAGGACGTGGACCACGTCAACGCGCACGGGACAGCAACGCCGATCGGCGACAGCGCGGAGGCCAACGCCATCAGGGTCGCCGGTTGCGAACAGGCTGCGGTGTATGCGCCAAAGTCAGCACTGGGCCACTCCATCGGCGCGGTCGGCGCGCTTGAGTCTGTCCTGACGGTGCTGGCCCTTCGCGACGGTGTCATCCCACCCACACTGAACTACCAAACCCCAGATCCCGAGATCGACCTAGACATTGTCGCAGGTGAACCTCGCTACGGCGACTACCGTTACGCGATCAATAACTCCTTCGGGTTCGGTGGCCACAACGTGGCGCTCGCTTTTGGGCGCTACTAAGCACGGG

Protein Sequence 

>ML1655_KasA_protein
CLPLLMAVSPVLW_PLSQQRRQSRRTSKARGRVCWPARAASTYSKTSTSPSGTCQSRSAATSRSQSIAT_AAWTCGACRTSSG_ASCSAVDYGSPPAARRSIPTGSPSWSAPVWAAPSESWKATT__TRADPVRCPRSPFR_SCPTAPQRPSGYSLGHAPG__HRCRPARRALRQSHTPGARSSWEMQMSPSVAVSRARSRRCLSRRSR_CEPCRPVTTTPRGHLGHSTKIVTGLCSAKPEP_CSSRLRSTPRLAAPSRWLGCLVQASPRTPFIWWHPRPTACEQGGQ_PGRWSWRVCRRRTWTTSTRTGQQRRSATARRPTPSGSPVANRLRCMRQSQHWATPSARSARLSLS_RCWPFATVSSHPH_TTKPQIPRST_TLSQVNLATATTVTRSITPSGSVATTWRSLLGATKHG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding KasA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

12 show weak predicted evidence for PPIs

View all pooled AlphaFold results for KasA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.