kasB
mL1656
3-oxoacyl-[acyl-carrier-protein] synthase 2 KasB (BETA-KETOACYL-ACP SYNTHASE) (KAS I)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 1996143 – 1997420
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1656_kasB_dna
CTAGACTCATGACCACATCGCCGGAGCTGGTTACAGGGAAAGCCTTTCCCAATGTGGTCGTCACCGGCATTGCTATGACGACTGCGCTGGCAACAGACGCGGAGACCACGTGGAAGTTGTTGCTCGACAACCAAAGTGGAATTCGTATGCTCGACGACCCGTTCATCGAGGAGTTCAACCTACCGGTTCGCATCGGTGGACATTTGCTGGAGGAATTCGACCACCAGCTGACCCGCGTCGAGCTGCGCAGGATGGGTTACCTACAGAGAATGTCCACCGTGCTAAGCCGGCGACTGTGGGAGAACGCGGGCTCACCCGAAGTGGACACCAATCGGTTAATGGTGTCCATCGGCACCGGGTTGGGCTCGGCCGAGGAGCTGGTCTTCAGCTACGACGACATGCGTGCGCGCGGAATGAAGGCAGTCTCGCCACTGGCCGTGCAGAAGTACATGCCCAACGGTGCGGCAGCGGCCGTCGGGCTGGAGCACCACGCCAAGGCTGGGGTGATGACGCCTGTGTCGGCGTGTGCGTCCGGTTCCGAGGCCATCGCCCATGCGTGGCAGCAGATCGTGCTCGGCGAAGCCGACTCGGCGATCTGTGGTGGCGTGGAAACAAAGATCGAGGCCGTGCCAATCGCCGGGTTCTCCCAGATGCGCATCGTAATGTCCACCAAGAACGACAACCCCGCCGGTGCATGTCGCCCGTTCGATAGGGACCGCGACGGCTTCGTGTTCGGTGAGGCCGGCGCGCTCATGCTAATCGAGACCGAGGACAGTGCGAAGGCGCGCAGCGCCAACATCCTAGCCCGGATCATGGGGGCCAGCATCACCTCGGACGGCTTCCACATGGTGGCACCGGACCCCAACGGGGAACGTGCCGGGCATGCTATCGCACGTGCAGTGCACCTAGCGGGCCTCAGTCCGAGCGACATCGACCACGTCAACGCCCATGCCACCGGCACCCAGGTCGGTGACCTGGCCGAAGCCAAAGCCATCAACAAAGCCCTCTGCAACAATCGACCGGCGGTGTACGCACCCAAATCTGCCCTCGGCCATTCAGTGGGCGCAGTCGGCGCGGTGGAATCAATCTTGACTGTGCTGGCGTTGCGGGACCAGGTAATCCCACCGACACTGAACCTGGTAAACCTCGATCCAGATATTGACTTGGACGTGGTAGCGGGTAAACCACGGCCGGGTGATTATCGGTATGCGGTCAACAACTCGTTCGGATTCGGCGGTCACAACGTAGCGATCGCCTTCGGCTGCTACTAACCCGAAC

Protein Sequence 

>ML1656_KasB_protein
LDS_PHRRSWLQGKPFPMWSSPALL_RLRWQQTRRPRGSCCSTTKVEFVCSTTRSSRSSTYRFASVDICWRNSTTS_PASSCAGWVTYRECPPC_AGDCGRTRAHPKWTPIG_WCPSAPGWARPRSWSSATTTCVRAE_RQSRHWPCRSTCPTVRQRPSGWSTTPRLG__RLCRRVRPVPRPSPMRGSRSCSAKPTRRSVVAWKQRSRPCQSPGSPRCAS_CPPRTTTPPVHVARSIGTATASCSVRPARSC_SRPRTVRRRAAPTS_PGSWGPASPRTASTWWHRTPTGNVPGMLSHVQCT_RASVRATSTTSTPMPPAPRSVTWPKPKPSTKPSATIDRRCTHPNLPSAIQWAQSARWNQS_LCWRCGTR_SHRH_TW_TSIQILTWTW_RVNHGRVIIGMRSTTRSDSAVTT_RSPSAATNPN

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding KasB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

10 show weak predicted evidence for PPIs

View all pooled AlphaFold results for KasB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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