ppk
mL1681
PROBABLE POLYPHOSPHATE KINASE PPK (POLYPHOSPHORIC ACID KINASE) (ATP-POLYPHOSPHATE PHOSPHOTRANSFERASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2025422 – 2027641
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1681_ppk_dna
GCAATGATCTTTTGGTGACCGACATCGAAGCTGAGGCCCGTACCGAAGAGAATATATGGCATTCAGACAACTCCGCCCTCGCAGCACCGCCCGCGGCGACCACCTCTGCGAGTCAGGACCAGCTGCCCGACGACCGCTACCTCAACCGGGAATCAAGTTGGCTGGATTTCAATGCGCGTGTGCTCGCACTAGCCGCCGATAACTCGTTGCCTTTGTTGGAGCGAGCCAAGTTTCTGGCTATCTTCGCATCCAATCTCGACGAGTTCTACATGGTTCGAGTCGCCGGCCTCAAGCGCCGCGACGAGATGGACTTGTCGGTGCGCTCTGCTGACGGTCTCACCCCACGTGAGCAACTGAGCCGCATAGGCGAGCAGACCCAATGGATCGCCAGCCGGCACGCGCGGGTGTTCCTCGATTCGGTGTTACCCGCACTCGGTGAGGAGGGTATCTACATTGTCACGTGGACGGATTTAGATCAGGCCGAACGTGACCAGTTATCGACCTATTTCAACGAGCAGGTCTTCCCCGTCCTGACACCACTGGCTGTCGATCCCGCCCACCCGTTTCCGTTTGTCAGCGGGTTAAGTCTGAACCTGGCTGTCACCGTCAAGCAACCCGAAGACGGTACCCAGCATTTCGCCCGGGTCAAAGTGCCTAACAACGTCGATCGATTCGTAGAACTCGCTAACCGCGGGGCGGTCAGAGATACCTCTGCCGGAGATGAAGGTCAGCTCATTCACCGGTTCCTGCCCATGGAGGAGCTGATCGCGGCATTCCTTCCGGTGCTCTTCCCTGGCACGGAAATCGTCGAGCATCATGCATTCCGCATTACCCGCAACGCTGACTTCGAGGTTGAAGAAGACCGTGACGAAGACCTACTACAGGCGCTGGAACGAGAATTGGCGCGTCGACGGTTCGGTTCGCCGGTGCGACTCGAGATCGCCGACGACATGACCGAGAGCATGCTGGAACTGCTGTTGCGGGAACTCGACGTGCATCCCAGCGACGTCATCGAAGTGCCCGGGCTGCTTGACCTGTCGTCGTTGTGGCAAATTTACGGGCTGGACCGACCCGCACTCAAAGACCGCGCATTCATTCCCGACACTCATCCCGCTTTCGCCGAACGGGAAACTCCCAAGAGCATCTTCGCGACGCTGCGCGAAGGCGATGTTCTGGTGCACCATCCCTATCACTCGTTTGCCACCAGCGTGCAGAGATTCATTGAACAGGCCACCGCCGACCCCGATGTGCTGGCGATCAAACAAACGCTGTACCGCACCTCCGGTGATTCACCGATCGTGCTGGCGCTCATCGAAGCTGCCGAGGCAGGAAAGCAAGTGGTGGCACTGGTCGAAATCAAGGCTCGCTTTGACGAGCAGGCCAACATCCGGTGGGCGCGCGCGCTGGAACACGCAGGCGTGCATGTGGTGTACGGGATCGTTGGGCTCAAGACACACTGCAAGACCTGCCTCGTGGTGCGCCGTGAGGGCCCGACGATCCGGCGGTACTGCCATATCGGAACCGGCAACTACAACAGCAAGACCGCTCGACTGTACGAAGATGTCGGTCTGTTGACCGCAGCACCCGATATCGGCGCCGACTTGACTGACTTGTTCAACTCGCTTACCGGCTACTCGCGTAAGCTGGCTTACCGCAACCTTCTGGTGGCACCGTATGGAATTCGCCGAGGCATTATCGAGCGGGTCGAGCGCGAGGTGGCCGCCCATCGCGAATCCGGCCCCCAAACCGGTAAGGGCCTGATCCGACTCAAGATGAACGCTCTGGTCGACGAACAAGTTATCGATGCGCTGTATCGCGCGTCACAGGCAGGCGTGCGGGTCGAGGTGGTGGTGCGCGGCATCTGCGCACTACGCCCAGGCACCGAAGGTTTTTCGGAAAACATTTTCGTCCGCTCGATTCTCGGCCGTTTCCTCGAGCATTCACGGATCATCCATTTCCGAGCCATCGATGAGTTCTGGATCGGAAGCGCCGACATGATGCACCGCAACCTAGATCGACGAGTCGAGGTGCTGGCGCAAGTTAAAGACTCGAGGCTGACCGCGCAGCTAGATGAGTTGTTGAAGTCCGCGCTGGACCCGTTCACCCGGTGTTGGGAACTGCGACCCGACGGGCAGTGGACCGCTTCGCCGCAGAAAGGCCAGCAGGTGCGCGACCACCAAGAATCGTTGATGGAACGGCACCGCAGCCGCTGACGCTGTG

Protein Sequence 

>ML1681_Ppk_protein
AMIFW_PTSKLRPVPKRIYGIQTTPPSQHRPRRPPLRVRTSCPTTATSTGNQVGWISMRVCSH_PPITRCLCWSEPSFWLSSHPISTSSTWFESPASSAATRWTCRCALLTVSPHVSN_AA_ASRPNGSPAGTRGCSSIRCYPHSVRRVSTLSRGRI_IRPNVTSYRPISTSRSSPS_HHWLSIPPTRFRLSAG_V_TWLSPSSNPKTVPSISPGSKCLTTSIDS_NSLTAGRSEIPLPEMKVSSFTGSCPWRS_SRHSFRCSSLARKSSSIMHSALPATLTSRLKKTVTKTYYRRWNENWRVDGSVRRCDSRSPTT_PRACWNCCCGNSTCIPATSSKCPGCLTCRRCGKFTGWTDPHSKTAHSFPTLIPLSPNGKLPRASSRRCAKAMFWCTIPITRLPPACRDSLNRPPPTPMCWRSNKRCTAPPVIHRSCWRSSKLPRQESKWWHWSKSRLALTSRPTSGGRARWNTQACMWCTGSLGSRHTARPASWCAVRARRSGGTAISEPATTTARPLDCTKMSVC_PQHPISAPT_LTCSTRLPATRVSWLTATFWWHRMEFAEALSSGSSARWPPIANPAPKPVRA_SDSR_TLWSTNKLSMRCIARHRQACGSRWWCAASAHYAQAPKVFRKTFSSARFSAVSSSIHGSSISEPSMSSGSEAPT_CTAT_IDESRCWRKLKTRG_PRS_MSC_SPRWTRSPGVGNCDPTGSGPLRRRKASRCATTKNR_WNGTAAADAV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Ppk with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

51 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Ppk

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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