hupB
mL1683c
PROBABLE DNA-BINDING PROTEIN HU HOMOLOG HUPB (HISTONE-LIKE PROTEIN) (HLP) (21-KDA LAMININ-2-BINDING PROTEIN)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2028724 – 2029326
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1683c_hupB_dna
GATTTGGATGAACAAAGCAGAGCTCATTGACGTGCTGACACAGAAATTGGGCTCGGACCGTCGGCAGGCGACCGCTGCCGTCGAGAATGTCGTTGACACCATTGTGCGTGCTGTACACAAGGGCGACAGCGTCACCATTACCGGGTTCGGTGTGTTCGAGCAGCGTCGCCGGGCTGCGCGCGTGGCTCGTAACCCCCGTACCGGCGAAACGGTGAAGGTGAAGCCGACGTCCGTCCCGGCGTTTCGTCCGGGTGCGCAATTTAAAGCGGTTGTGGCTGGCGCACAGCGTCTCCCGTTGGAAGGTCCCGCTGTCAAGCGTGGTGTAGCGACCAGCGCTGCCAAGAAGGCAGCGATTAAGAAGGCTCCGGTTAAGAAGGCGCTGGCCAAGAAGGCGGCGACCAAGGCTCCGGCCAAGAAGGCCGTGAAGGCGCCCGCCAAGAAAATCACCACGGCCGTGAAAGTTCCGGCTAAAAAGGCGACAAAAGTGGTCAAGAAGGTCGCCGCCAAGGCTCCGGTACGCAAGGCCACGACCAGGGCGCTGGCCAAGAAGGCAGCGGTGAAGAAGGCTCCTGCCAAGAAGGTTACCGCAGCTAAGCGGGGTCG

Protein Sequence 

>ML1683c_HupB_protein
DLDEQSRAH_RADTEIGLGPSAGDRCRRECR_HHCACCTQGRQRHHYRVRCVRAASPGCARGS_PPYRRNGEGEADVRPGVSSGCAI_SGCGWRTASPVGRSRCQAWCSDQRCQEGSD_EGSG_EGAGQEGGDQGSGQEGREGARQENHHGRESSG_KGDKSGQEGRRQGSGTQGHDQGAGQEGSGEEGSCQEGYRS_AGS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding HupB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

7 show weak predicted evidence for PPIs

View all pooled AlphaFold results for HupB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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