leuD
mL1684c
PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2029540 – 2030136
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1684c_leuD_dna
ATAAATTATGCAAGCTTTCCGCGTCCATACCGGTATCGGCGTGCCGTTGCGGCGGTCCAATGTCGATACCGATCAGATCATTCCGGCGGTCTTTTTGAAGCGTGTCACTCGAAACGGTTTCGAGGACGGCTTGTTCGCTACGTGGCGGGTCGATCCCTCATTCGTGCTCAACCTCAGCCCCTTTGATCGGGGCTCAGTCCTGGTCGTCGGTCCTGATTTCGGGATCGGGTCGTCGCGTGAGCATGCGGTGTGGGCGCTCATGGACTACGGATTCCGGGTGGTTATCTCGTCTCGATTTGGTGATATTTTTCACGGTAACGCGGGCAAGGCGGGGTTGCTGGCAGCTCAAGTAGCCCAAGATGATGTCGAATTTCTGTGGAAACTCATCGAGCAGAAGCCGGGGTTGGAAATCACTGTCAATCTTCAAGATCGAAATATCAATGCTGCAACGGTGGTGTTGCCGTTCAAGATTGATGACTACACTGCTTGGCGATTGCTCGAAGGACTCGACGATATAGCTCTTAATCTGCGGAAACTTGACGAGATCGAGGCGTTTGAGTCGGCGCGTCCTGCGTGGAAACCGCGCACCCTGCCCAC

Protein Sequence 

>ML1684c_LeuD_protein
INYASFPRPYRYRRAVAAVQCRYRSDHSGGLFEACHSKRFRGRLVRYVAGRSLIRAQPQPL_SGLSPGRRS_FRDRVVA_ACGVGAHGLRIPGGYLVSIW_YFSR_RGQGGVAGSSSSPR_CRISVETHRAEAGVGNHCQSSRSKYQCCNGGVAVQD__LHCLAIARRTRRYSS_SAET_RDRGV_VGASCVETAHPAH

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LeuD with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

55 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LeuD

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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