gltS
mL1688c
PROBABLE GLUTAMYL-TRNA SYNTHETASE GLTS (GLUTAMATE--TRNA LIGASE) (GLUTAMYL-TRNA SYNTHASE) (GLURS)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2033591 – 2035099
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1688c_gltS_dna
GAAAGTCGTGACTGCAGTAACCTCTGATGGTACCCCGCAAGCAGCAAAAGTCAGGGTACGATTCTGCCCATCGCCCACTGGTGTTCCGCACGTCGGGATGGTTCGCACGGCCCTGTTCAACTGGGCTTACGCTCGACATACTGGAGGCACCTTCGTCTTACGCATCGAGGACACCGACGCCGACCGCGACAGTGAAGAAAGCTACCTGGCCCTGCTCGATGCGTTGCGCTGGCTCGGCCTGAACTGGGACGAGGGTCCCGAGGTTGGAGGACCTTACGGTCCGTACCGGCAGTCGCAGCGCACTGACATCTACCGCGAGGTGGTGGCAAAGTTGCTTGCTACAGGAGAGGCCTATTACGCTTTCTCCACACCGGAGGAAGTCGAGAACCGCCATCTTGCTGCTGGACGCAATCCCAAGCTGGGTTATGACAACTTTGACCGCGATCTTACCGATGCGCAGTTCTCAGCGTACTTGGCGGAAGGCCGTAAGCCTGTAGTTCGGCTGCGGATGCCCGACGAGGATATCAGTTGGGATGACCTGGTGCGCGGGACAACTACCTTTGCTGTGGGCACTGTGCCCGATTACGTGTTGACCCGAGCAAGCGGAGATCCGTTGTACACTTTGGTCAACCCGTGCGATGACGCGCTGATGAAGATCACGCATGTACTGCGGGGCGAAGACTTACTATCGTCGACTCCGCGACAGGTGGCGCTATACCAGGCGTTGATCCGAATCGGGATGGCTGAGCGTATTCCCGAATTCGGTCATTTCCCATCGGTATTGGGGGAGGGAACCAAGAAACTCTCGAAGCGAGAACCGCAGTCGAATTTGTTTGCCCACCGTGACCGGGGCTTTATCCCCGAAGGTCTGCTGAACTACCTTGCCTTGCTGGGGTGGGCGATCGCCGATGACCACGACTTGTTCAGTCTCGATGAGATGGTAGCCGCGTTCGATGTGGTCGACGTCAACTCCAATCCGGCGCGATTCGATCAGAAGAAGGCCGATGCGGTTAACGCCGAGCACATCCGAATGCTCGACTCCGAGGATTTCGCTGGCAGGCTACGCGACTACTTCACCACACACGGCTACCACATCGCTTTGGATCCCGCTAATTACGAAGCTGGTTTCGTTGCCGCGGCGCAGTTGGTGCAGACCCGCATCGTTGTGCTTGGTGACGCTTGGGACCTGTTGAAATTCCTCAACGATGACGAGTACTCTATCGACTCTAAGGCCGCTGCCAAAGAACTGGATGCCGATGCCGGGCCGGTGCTTGATGTTGCCTGTGCCGTGCTGGACAGCCTGGTGGATTGGACCACTGCGAGTATCGAGGACGTCCTCAAGGTTGCACTCATCGAAGGTCTTGGTCTTAAACCGCGCAAAGTGTTTGGCCCGATCCGGGTCGCCGCCACGGGGGCATTGGTCAGCCCGCCGCTGTTCGAATCGCTGGAGCTACTCGGCCGTGCTCGCAGTCTGCAGCGGCTGAGTGCTGCGCGAGCGCGAGTCACCTC

Protein Sequence 

>ML1688c_GltS_protein
ESRDCSNL_WYPASSKSQGTILPIAHWCSARRDGSHGPVQLGLRSTYWRHLRLTHRGHRRRPRQ_RKLPGPARCVALARPELGRGSRGWRTLRSVPAVAAH_HLPRGGGKVACYRRGLLRFLHTGGSREPPSCCWTQSQAGL_QL_PRSYRCAVLSVLGGRP_ACSSAADARRGYQLG_PGARDNYLCCGHCARLRVDPSKRRSVVHFGQPVR_RADEDHACTAGRRLTIVDSATGGAIPGVDPNRDG_AYSRIRSFPIGIGGGNQETLEARTAVEFVCPP_PGLYPRRSAELPCLAGVGDRR_PRLVQSR_DGSRVRCGRRQLQSGAIRSEEGRCG_RRAHPNARLRGFRWQATRLLHHTRLPHRFGSR_LRSWFRCRGAVGADPHRCAW_RLGPVEIPQR_RVLYRL_GRCQRTGCRCRAGA_CCLCRAGQPGGLDHCEYRGRPQGCTHRRSWS_TAQSVWPDPGRRHGGIGQPAAVRIAGATRPCSQSAAAECCASASHL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GltS with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

38 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GltS

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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