leuB
mL1691c
PROBABLE 3-ISOPROPYLMALATE DEHYDROGENASE LEUB (BETA-IPM DEHYDROGENASE) (IMDH) (3-IPM-DH)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2037162 – 2038172
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1691c_leuB_dna
GGGGCAGATGAAATTGGCGATCATCGGTGGCGACGGGATCGGCCCGGAGGTGGTCGCACAGGCAGTCAAAATTCTTGATGTGGTGCTGCCGGGCGTACAGAAGACTACCTACGATCTGGGCGCCCGGCGTTATCACACCACTGGTGAGCTATTGCCGGAGTCGGTGCTCGCCGAGCTACGGGAGCACGACGCCATCTTGCTCGGGGCGGTAGGTGATCCCTCAGTCCCTAGTGGTGTGTTGGAGCGGGGCTTGCTGCTGAGATTGCGCTTCGAGCTGGATCATCATATCAATCTGCGACCGGCCCGGTTGTATCCAGGTGTTAACAGTTTGCTTGCGGGAAAGCCCGATATTGACTTTGTGGTGGTTCGCGAGGGCACCGAAGGCCCCTACACTGGTACCGGCGGTGCGATCCGTGTCGGAACCCCTAACGAGGTGGCCACGGAGGTAAGTGTGAATACCGCTTTTGGTGTGCGCCGGGTGGTGCAAGATGCGTTCGAACGTGCCCGACAGCGCCGCAAGCATCTGACGCTGGTACACAAGAACAACGTGCTGACCTATGCCGGGACGTTGTGGTGTAGGATCGTGCAGGAGGTCGGTGAAAAATACCCCGACGTCGAGGTTGTCTACCAGCATATAGATGCGGCCACCATCTACTTGGTCACCGAACCCAGTCGCTTTGATGTCATTGTCACTGATAACCTATTCGGTGATATCATCACCGACTTGGCCGCAGCGGTGTGTGGTGGCATTGCCTTGGCCGCCAGTGGAAATATCGATGCCACCCGGACCAATCCGTCGATGTTCGAGCCGGTGCATGGCAGCGCTCCGGATATTGCCGGCCAGGGCATCGCTGATCCGACCGCGGCGATAATGTCGTTGGCACTGCTGCTCGCCCATCTCGGTGAGGATGAGCCGGCTGCTCGGTTGGACCAGGCGGTAGCGAGTTATTTGGCGACTCGCGGGAACGGGCGGTTTTCCACCGGCGAAGTTGGAGAACGAATAGCCGCTGC

Protein Sequence 

>ML1691c_LeuB_protein
GADEIGDHRWRRDRPGGGRTGSQNS_CGAAGRTEDYLRSGRPALSHHW_AIAGVGARRATGARRHLARGGR_SLSP_WCVGAGLAAEIALRAGSSYQSATGPVVSRC_QFACGKARY_LCGGSRGHRRPLHWYRRCDPCRNP_RGGHGGKCEYRFWCAPGGARCVRTCPTAPQASDAGTQEQRADLCRDVVV_DRAGGR_KIPRRRGCLPAYRCGHHLLGHRTQSL_CHCH__PIR_YHHRLGRSGVWWHCLGRQWKYRCHPDQSVDVRAGAWQRSGYCRPGHR_SDRGDNVVGTAARPSR_G_AGCSVGPGGSELFGDSRERAVFHRRSWRTNSRC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding LeuB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

14 show weak predicted evidence for PPIs

View all pooled AlphaFold results for LeuB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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