ilvC
mL1694c
PROBABLE KETOL-ACID REDUCTOISOMERASE ILVC (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2042727 – 2043728
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1694c_ilvC_dna
ACTATCATTGTTCTACGACGACAATGCAGATCTGTCGATCATTCAGCGACGCAAAGTCGGCGTGATCGGATACGGCAGCCAGGGGTACGCGCACTCGCTGAGTCTGCGCGATTCTGGTGTCCAGGTGCGGGTCGGTCTGCCGGAGGGCTCGAAGTCTCGGCCTAAGGCCTTCGAGCAGGGCCTGGACGTCGATACCCCTGCCGAGGTCGCCAAGTGGGCCGATGTCATCATGCTGTTGGTGCCTGACACTGCGCAGGCGGACGTCTTTGAAAACGATATCGAGCCCAACCTCCAGCCTGGCGATGCTTTGTTTTTCGGTCATGGACTCAACATTCACTTCGAACTGGTCAAGCCGTCGGGCGATGTGACCGTCGCGATGGTCGCACCGAAGGGTCCCGGCTACCTGGTGCGCCGCCAGTTCGTTGATGGCAAGGGTGTGCCTTGCCTGATCGCCGTTAACCAAGACCCGACCGGCACCGGCGAGGCGCTGGCGTTGTCTTACGCTAAAGCTATCGGCGGCACCCGTGCCGGCGTCATCAAGACTACCTTCAAAGACGAGACAGAAACTGATCTTTTCGGTGAGCAGGCCGTATTATGCGGTGGTACAGAGGAATTGGTGAAGGCAGGTTTCGACGTCATGGTCGAAGCGGGCTACCCTCCCGAGATGGCGTACTTCGAGGTGCTGCACGAACTTAAGCTGATCGTCGATCTGATGTACGAGGGCGGGATCGCGCGGATGAACTACTCGGTGTCTGACACCGCTGAGTTTGGTGGGTACCTGTCAGGTCCGCGTGTCATCGATGCTGACACCAAGGAGCGGATGCGCGGCATTCTGCGCGACATCCAGGACGGCAGTTTCGTCAAGAAGCTGGTCGCCAACGTTGAGGGCGGAAACAAGCAACTCGAAGTGCTCCGTAAGGAAAACGCCGAACATCCCATCGAGGTTACCGGCAAAAAGTTGCGCGACCTGATGAGCTGGGTTGACCGCCAGAGCACCGAGAC

Protein Sequence 

>ML1694c_IlvC_protein
TIIVLRRQCRSVDHSATQSRRDRIRQPGVRALAESARFWCPGAGRSAGGLEVSA_GLRAGPGRRYPCRGRQVGRCHHAVGA_HCAGGRL_KRYRAQPPAWRCFVFRSWTQHSLRTGQAVGRCDRRDGRTEGSRLPGAPPVR_WQGCALPDRR_PRPDRHRRGAGVVLR_SYRRHPCRRHQDYLQRRDRN_SFR_AGRIMRWYRGIGEGRFRRHGRSGLPSRDGVLRGAART_ADRRSDVRGRDRADELLGV_HR_VWWVPVRSACHRC_HQGADARHSARHPGRQFRQEAGRQR_GRKQATRSAP_GKRRTSHRGYRQKVARPDELG_PPEHRD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding IlvC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

10 show weak predicted evidence for PPIs

View all pooled AlphaFold results for IlvC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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