ilvN
mL1695c
PROBABLE ACETOLACTATE SYNTHASE (SMALL SUBUNIT) ILVN (ACETOHYDROXY-ACID SYNTHASE) (AHAS) (ALS)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2043781 – 2044290
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1695c_ilvN_dna
GCGCATAATGGTAGGGTTGCCAACGCACACCTTGTCGGTTCTGGTCGAGGACACTCCCGGCGTGCTCGCGCGGGTGGCGGCACTGTTCTCTCGGCGCGGTTTCAATATTGAGTCGTTGGCTGTCGGTGCTACTGAGTGCAAGACTATGTCGCGAATGACCATCGTTGTCTCTGCCGAGGAGACCCCGCTCGAGCAGGTCACCAAGCAGCTGCACAAGTTGATTAACGTCATCAAGGTTGTTGAGCAAGAGGCTGACAACTCGCTGTCCCGCGAGCTGGCGTTGATCAAGGTGCGGGCCGAAGCTGGTACCCGCAGCCAGGTAATCGAAGCGGTACACTTGTTCCGCGCCAGGGTTATTGATGTATCGCTCGAGTCACTGACTGTCGAGGCCACTGGTGACTGCAGCAAAATTGAGGCGTTGCTGCGTGTGCTGGAGCCTTTCGGCGTACGAGAAATCGTCCAATCGGGAGTGGTCTCGTTATCTCGCGGTCCGCGCGGTATCGGCACAGT

Protein Sequence 

>ML1695c_IlvN_protein
AHNGRVANAHLVGSGRGHSRRARAGGGTVLSARFQY_VVGCRCY_VQDYVANDHRCLCRGDPARAGHQAAAQVD_RHQGC_ARG_QLAVPRAGVDQGAGRSWYPQPGNRSGTLVPRQGY_CIARVTDCRGHW_LQQN_GVAACAGAFRRTRNRPIGSGLVISRSARYRHS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding IlvN with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

38 show weak predicted evidence for PPIs

View all pooled AlphaFold results for IlvN

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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