ilvB
mL1696c
PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB (ACETOHYDROXY-ACID SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2044342 – 2046219
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1696c_ilvB_dna
ACACACAGTGAGCGCACCGACCAAGCCACACGCCCGCCCGCAGGGGGCGGGTAACAGCGTGCCAAACACCGTGAAACCCGCCACGCAATTTCCCTCAAAGCCAGCTGTCGCAAAACTAGAACGCGTTTCACCTGAGCAACTTACCGGTGCTCAATCGGTGATTCGGTCGTTGGAAGAACTCGATGTCGAGGTCATCTTCGGAATTCCCGGCGGTGCCGTCCTTCTGGTATATGACCCGCTGTTCTACTCAAAAAAGTTACGTCATGTCCTGGTCCGCCACGAGCAGGGCGCCGGCCACGCGGCCAGCGGCTACGCACACGTGACCGGCAAGGTGGGGGTGTGCATGGCGACTTCTGGTCCTGGAGCCACCAATCTGGTGACACCGTTGGCCGATGCGCAGATGGACTCAGTGCCGGTGGTCGCCATTACTGGGCAGGTCGGGCGCAGTCTGATCGGGACGGATGCCTTCCAAGAGGCCGACATCTCCGGCATCACAATGCCGATAACCAAGCATAACTTTCTGGTTCGTGCCGGCGACGATATTCCCCGGGTACTGGCTGAGGCCTTCCACATCGCGTCGTCGGGACGGCCGGGTGCGGTGCTCGTCGATATCCCGAAGGATGTGCTGCAGGGCCAGTGCAAGTTCAGCTGGCCACCGAAAATGGACTTGCCCGGGTACAAGCCGAACACCAAACCGCACAACCGGCAGATCCGTGCGGCAGCCAAGCTGATCGCTGACGCCCGCAAGCCTGTGCTGTATGTCGGCGGGGGCGTTATCCGCGGCGAAGCGACCGAGCAGCTACGGGATTTGGCCGAACTGACCGGCATCCCGGTGGTTAGCACGTTGATGGCACGTGGCGCGTTCCCCGACAGCCATCACCAGAACTTGGGCATGCCCGGCATGCACGGCACCGTTGCGGCGGTGGCAGCGCTGCAGCGCAGCGATTTACTGATCGCACTGGGCACTCGCTTTGACGACCGGGTGACTGGCAAGCTCGACTCCTTCGCGCCCGACGCCAAGGTTATACATGCCGACATCGACCCGGCGGAGATCGGCAAGAACCGGCACGCTGACGTGCCGATTGTGGGCGACGTCAAAGCTGTTATTGTAGAGCTCATCGCGATGCTGCGCCATTACGAGGTCCCCGGCAACATCGAAATGACCGACTGGTGGTCATATTTGGACGGTGTTCGCAAGACGTATCCGTTGAGCTACAGTCCACAAAGCGACGGCACTCTGAGCCCGGAGTACGTTATCGAAAAGCTTGGTGAAATTGTTGGCCCGGAGGCCGTATATGTCGCGGGTGTAGGTCAGCATCAGATGTGGGCGGCGCAGTTCATCTCCTACGAGAAGCCGCGTACTTGGCTCAACTCAGGCGGTCTGGGCACCATGGGGTTTGCTATTCCGGCGGCCATGGGCGCCAAGATTGCTCGCCCGGAGGCAGAAGTCTGGGCGATCGACGGCGATGGCTGCTTCCAGATGACCAACCAGGAGTTGGCTACGTGCGCTATCGAGGGCGCGCCGATCAAGGTGGCGTTGATCAACAACGGCAACCTGGGCATGGTGCGGCAATGGCAAGCCTTGTTTTATCAGGAGCGTTACTCGCAGACCGACCTGGCCACCCACTCACACCGCATTCCGGACTTCGTGAAGTTGGCCGAGGCGTTGGGTTGCGTCGGATTGCGTTGCGAGTGTGAAGAGGACGTTGTCGATGTGATCAATCAGGCCAGGGCGATCAACAACCGCCCTGTGGTGATCGACTTCATCGTCGGCGCCGATGCGCAGGTGTGGCCGATGGTCGCCGCTGGGGCCAGCAACGACGAGATCCAAGCTGCCCGCGGTATCCGCCCGCTCTTTGATGACGAAAGCGAAGGGCA

Protein Sequence 

>ML1696c_IlvB_protein
THSERTDQATRPPAGGG_QRAKHRETRHAISLKASCRKTRTRFT_ATYRCSIGDSVVGRTRCRGHLRNSRRCRPSGI_PAVLLKKVTSCPGPPRAGRRPRGQRLRTRDRQGGGVHGDFWSWSHQSGDTVGRCADGLSAGGRHYWAGRAQSDRDGCLPRGRHLRHHNADNQA_LSGSCRRRYSPGTG_GLPHRVVGTAGCGARRYPEGCAAGPVQVQLATENGLARVQAEHQTAQPADPCGSQADR_RPQACAVCRRGRYPRRSDRAATGFGRTDRHPGG_HVDGTWRVPRQPSPELGHARHARHRCGGGSAAAQRFTDRTGHSL_RPGDWQARLLRARRQGYTCRHRPGGDRQEPAR_RADCGRRQSCYCRAHRDAAPLRGPRQHRNDRLVVIFGRCSQDVSVELQSTKRRHSEPGVRYRKAW_NCWPGGRICRGCRSASDVGGAVHLLREAAYLAQLRRSGHHGVCYSGGHGRQDCSPGGRSLGDRRRWLLPDDQPGVGYVRYRGRADQGGVDQQRQPGHGAAMASLVLSGALLADRPGHPLTPHSGLREVGRGVGLRRIALRV_RGRCRCDQSGQGDQQPPCGDRLHRRRRCAGVADGRRWGQQRRDPSCPRYPPAL__RKRRA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding IlvB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

53 show weak predicted evidence for PPIs

View all pooled AlphaFold results for IlvB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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