pfkA
mL1701c
PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2052005 – 2053036
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1701c_pfkA_dna
TGAAGGCATGAGGATCGGAATTCTCACGGGGGGCGGCGACTGTCCTGGTCTTAACGCCGTTATCCGGGCGATTGTGCGCACCTGTGACGCCCGGTACGGTTCGTCGGTAGTCGGGTTTCAGGACGGCTGGCGTGGGTTGCTGGAGAATCGGCGCATGCAGCTGTGCAACGACGACCGGAATGACCGTCTGTTAGCCAAAGGCGGAACCATGCTGGGCACTGCCCACGTGCACCCCGACAAGCTGCGGGCCGGGCTGCATCAGATCAAGCAGACCCTGGATGACAATGGCATCGACGTGCTCATCCCGATCGGCGGCGAAGGCACGCTGACGGCCGCGCACTGGCTGTCGCAGGAAGACGTTCCTGTGGTCGGCGTGCCGAAGACGATCGACAACGACATCGACTGCACCGACGTGACCTTTGGCCACGACACCGCGCTGACGGTGGCTACCGAAGCCATTGACCGGTTGCACAGTACCGCCGAATCTCACCAACGTGTGATGCTGGTGGAGGTGATGGGTCGGCATGCCGGCTGGATAGCGCTGAGTTCCGGGCTGGCTTCCGGTGCGCACATGACGCTGATTCCCGAACAGCCCTTCGATGTCGAGGAAGTGTGCTGCCTCGTGAAACGACGTTTTCAGCGCGGGGATTCGCATTTCATTTGCGTGGTCGCTGAGGGTGCCAAGCCGGTCCCAGGCTCGATCACGTTGCGCCAAGGTGGGATGGATGAATTTGGTCACGAGCGTTTCACTGGGGTGGCAGCGCAATTGGGCGCTGAGGTCGAGAAGCGGATCAACAAGGACGTGCGAGTGACTGTGCTGGGTCATGTCCAACGCGGTGGTACACCGACGGCCTTCGATCGGGTGCTGGCCACCCGGTTCGGGGTTAATGCTGCCGACGCCTCGCACGCCGGCGAGTACGGCCAGATGGTGTCACTGCGTGGGCAAGACATCGGTCGCGTACCGCTGGAGGATGCGGTGCGTCAGCTCAAATTGGTGCCCGAAAGCCGTTACGACGACGCCGCCGCCTTCTT

Protein Sequence 

>ML1701c_PfkA_protein
RHEDRNSHGGRRLSWS_RRYPGDCAHL_RPVRFVGSRVSGRLAWVAGESAHAAVQRRPE_PSVSQRRNHAGHCPRAPRQAAGRAASDQADPG_QWHRRAHPDRRRRHADGRALAVAGRRSCGRRAEDDRQRHRLHRRDLWPRHRADGGYRSH_PVAQYRRISPTCDAGGGDGSACRLDSAEFRAGFRCAHDADSRTALRCRGSVLPRETTFSARGFAFHLRGR_GCQAGPRLDHVAPRWDG_IWSRAFHWGGSAIGR_GREADQQGRASDCAGSCPTRWYTDGLRSGAGHPVRG_CCRRLARRRVRPDGVTAWARHRSRTAGGCGASAQIGARKPLRRRRRLL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PfkA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

2 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PfkA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.