trmU
mL1707c
probable tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase TrmU
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2059823 – 2060899
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1707c_trmU_dna
TTGGGGTGTGAAAGTTCTCGCCGCGATGAGCGGTGGCGTCGACTCGTCGGTTGCTGCTGCCCGGATGGTCGACGCCGGACATGATGTGGTGGGTGTTCACCTGGCGCTGTCTACCGTCTCCGGTACGCTGCGCACCGGGTCACGGGGCTGCTGTTCCAAAGAAGACGTGTCAGATGCGCGCCGTGTTGCCGATGTCCTTGGGATCCCCTTTTATGTTTGGGATTTCGCCGAGAAGTTCCAAGAAGACGTGATCGATAATTTTGTGTCTGCGTATGCCCGCGGGGAAACCCCTAACCCCTGTGTGCAATGCAATCAGCGGATCAAGTTCTCGGCGCTTTCTGTCAGAGCCTTAATGTTGGGTTTCGATACGGTGGCCACTGGCCACTACGCGCGACTGTCCGGTGGGCGACTACGTCGTGCTGTCGACCGGGGTAAGGATCAATCCTACGTGCTGGCGGTATTGACTGCTCAACAGTTGCGCCACGCCGCGTTCCCGATCGGCGACACGCTCAAGCGGCAGGTTCGTGCGGAGGCCGCCCGCCGTGGCTTACTAGTCGCTGATAAGCCCGACAGCCACGGCATCTGCTTCATCCCGTCCGGGAACACCCGTGCTTTTTTGAGTGAATGTATTGGGATACGCCGCGGCAGTGTGGTTGACGCGGATGGCACGGTGCTTGCCGAGCATGATGGAGTACACGGTTTCACCGTAGGCCAACGCAAGGGTCTGGGCATCGTCGGGCCAGGACCGAACGGCCGTCCGCGCTATGTGACGGCGATTGACGCCGACACCGCGACCGTGTACGTGGGTGACGCGGCCGACCTCGGTGTGCATACGCTGATCGGACGGGCGCCGGTCTTCACCGCGGGAGCTGCGCCGTTGGGTCCTGTTCAGTGTGTGGTTCAGATTCGTGCACACGGTGAAACCGCCGTTGCGGTCGTTGAGTTGATTGGTGACGAGCTGTTTGTGCGGTTGTGCGAACCGCTGCGCGGTGTGGCGCGCGGCCAGACGTTGGTGCTGTACCGCTTGGATCCGGACGGGGACGAAGTGCTTGGCAGCGCCACTATAGCTAGCATGTC

Protein Sequence 

>ML1707c_TrmU_protein
LGCESSRRDERWRRLVGCCCPDGRRRT_CGGCSPGAVYRLRYAAHRVTGLLFQRRRVRCAPCCRCPWDPLLCLGFRREVPRRRDR_FCVCVCPRGNP_PLCAMQSADQVLGAFCQSLNVGFRYGGHWPLRATVRWATTSCCRPG_GSILRAGGIDCSTVAPRRVPDRRHAQAAGSCGGRPPWLTSR__ARQPRHLLHPVREHPCFFE_MYWDTPRQCG_RGWHGACRA_WSTRFHRRPTQGSGHRRARTERPSALCDGD_RRHRDRVRG_RGRPRCAYADRTGAGLHRGSCAVGSCSVCGSDSCTR_NRRCGR_VDW_RAVCAVVRTAARCGARPDVGAVPLGSGRGRSAWQRHYS_HV

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TrmU with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

53 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TrmU

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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