nrdF
mL1731c
RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (BETA CHAIN) NRDF (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R2F PROTEIN)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2090620 – 2091597
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1731c_nrdF_dna
TGGGGTTTTGTTGACTGGGAAGATGAAGCTAATTGACCGCGTTTCGGCGATTAATTGGAACTGGCTGCAAGACGACAAGGACGCCGAGGTCTGGGACCGGCTGACTGGAAACTTCTGGCTGCCCGAGAAGGTGCCGGTGTCCAACGATCTCCCGTCGTGGGGCACGCTGACTGCTAGTGAAAAGCAGCTGACAATGCGGGTGTTCACCGGTTTGACGCTGCTCGACACGATCCAAGGCACGGTCGGAGCGGTCAGCCTTATTCCTGATGCGCTAACGCCGCATGAGGAAGCCGTCTACACCAACATTGCATTCATGGAGTCGGTGCACGCCAAGAGCTACAGTTCGATCTTTTCCACGCTGTGCTCGACAGCGGAGATCGACGAAGCGTTTCGCTGGTCGGAGGAGAACAACAACCTGCAGCGCAAAGCTAAGATTGTGATGGAGTACTATCGAGGCGACGAACCGCTCAAGCGCAAGGTGGCCTCCACCTTGCTCGAAAGCTTCCTGTTTTACTCTGGGTTCTACCTGCCGATGTACTGGTCAAGTCGGGCCAAGCTGACCAACACCGCTGATATGATTCGGCTGATCATCCGCGACGAAGCAGTCCACGGTTACTATATCGGCTACAAATTTCAGCGTGGCTTGGTGTTGGTCGACGACGCCAGGCGGGCAGAACTCAAGGAATACACCTACGAATTGCTCTTTGAGCTCTACGACAACGAGGTGGAATACACCCAAGATCTCTACGACAGAGTCGGGTTGACCGAAGACGTCAAGAAGTTCTTGCGCTACAACGCAAATAAGGCGTTGATGAACCTTGGCTACGAGGCGCTGTTCCCGCGGGACGAGACCGACGTGAACCCGGCGATCCTGTCGGCCTTGTCTCCCAACGCCGATGAGAATCATGACTTTTTCTCCGGCTCGGGGTCGTCGTATGTGATCGGGAAAGCCGTCGTCACTGAGGACGAGGACTGGGA

Protein Sequence 

>ML1731c_NrdF_protein
WGFVDWEDEAN_PRFGD_LELAARRQGRRGLGPADWKLLAAREGAGVQRSPVVGHADC__KAADNAGVHRFDAARHDPRHGRSGQPYS_CANAA_GSRLHQHCIHGVGARQELQFDLFHAVLDSGDRRSVSLVGGEQQPAAQS_DCDGVLSRRRTAQAQGGLHLARKLPVLLWVLPADVLVKSGQADQHR_YDSADHPRRSSPRLLYRLQISAWLGVGRRRQAGRTQGIHLRIAL_ALRQRGGIHPRSLRQSRVDRRRQEVLALQRK_GVDEPWLRGAVPAGRDRREPGDPVGLVSQRR_ES_LFLRLGVVVCDRESRRH_GRGLG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding NrdF with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

4 show intermediate predicted evidence for PPIs

24 show weak predicted evidence for PPIs

View all pooled AlphaFold results for NrdF

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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