ML1753c
mL1753c
PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2123775 – 2127095
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1753c_ML1753c_dna
GGGAGACATGTATTCTTTGGGCGAGATGCAGAAACCAGTACCCGTTGGCGCTGATTATCTGGCTTCATGTCTGGTGGCGCGGCTGAGATCGACCGATGTACCGACGGACCTCCATCGCGGTTGCACGGTGACGTTGTTTCTGGGTGACGTCGAAGGCTTGGCAGAGCTGTCCGAAACACAACCCGATGAGGCAGCGGATGCAATCGCACGCCTGGACTGTGTGGTGTCAGAAGCTGTCGCGGCTCACGGCGGGGTGCAACAGGTTGTCCAAGGGGTAAGGGGAAACTTTCTCGCAACGTTTGCCCGTGCTAGCGACGCCACAGCGTGCGCATTAGACCTGCAGCTGGCCCCGATCGTACCAGTTCGGTTTCGTATCGCTCTGCACACCGGTGAGGTTCAGATATCCAACGATGATGTCAATAATGTGGTTTTTATGATGGTGCAGGCTGCAGGGTTGCTCGATTTGGCATGCGGGGGACAAACGGTGTTGTCATCTATCACAGGAGATCTCGTCGTTGATGGGCTCCCCGCTGATACCTGGCTGGTGGATCTTGGCAGTCACCTATTGCGGGATCTGGCTCGGCCAGTACGTGTCATGCAGTTGTGTCACCGTAATCTGCGCAGAAATCTTCACGAGCTAGGTATCCGGACTGTCCCTGGCGGACCAAGTCTTCCGGTGCCGCTCACCACTTTTGTTGGTCGCGCTGCGCAGATCAAAGAACTGCAAGAGCTGTTGACCGAAAAACGGTTGTTAACGCTGGTAGGTCCAGGGGGAGTAGGAAAAACGCGGCTCGCGTTACAGGTCGTCGCTAGGGTCGCAGACGAGTTTAGTGGTGAGCTGTCGTATTTCGACCTAGCTCCGGACACCGATCACGACATCTTTCCGATTACGGTGTTAGACAATCTGCGCCGGTGCATCGGTGACCGTCGCATGCTGATGGTGTTGGACAACTGCGAGTACCTTCTCGATGTGTGCGCGAATGTGATGACTACGCTGTTGGGCGCTTGTCCGTCGTTGACGATTTTGGCGACCAGTCGTGAGCCGATCGGGGTGGCCGGCGAAGTCATATGGCGGGTTTCAATGCTGTCTCCTGCCGACGAAGCGGTCGAATTATTCACAGAACGAGCTGCCTTGGTTCAACCCGGTTTCAGTGTTACCGATGGCAACCGTCAGATCGTGACCGAGATCTGTCAGCGCCTTGACGGCATGCCTTTGGCGATTGAGCTGGCCGCTGCACGGATACGTACGTTATCGTTAACTGAGATAGCCGATGGTTTGGATGACCGGTTTCGGCTGCTGACTGGTGGTGCGCGTACCGCGGTGCGACGTCAACAGACGCTCCGTGCCTCGATGGATTGGTCGTATGCATTGCTGACCGAAAGCGAGCGGGCCTTGTTTCGTCGCTTGTCGGCAATTTCGGGGACGTTCGACCTCAAGGTGGCCTATGCGGTTGGACACGATGATCTTGAGGAGCCTGATCAGGTTTTCGATCGGCTGACTATGCTCATAGACAAGTCTTTGGTCATAGTTGAAGGCAGACAGGGTGGCTCGCGGTACCGGTTGCTGGAAACGGTGCGCCAGTACGCGATGAAGAAGCTCGAAGAGTCCAATGAGGTCGACCTTGTGCTTGCCCGTCACCGCGATCACTACATGGCACTTGGGGCTTTGCTGGATACTCCGGGAGACATCGACCACGAGCAGCTTGTTGAGCAAGTTGAGACCGAGCTTGACAATCTGCGTAGCGCATTCGCATGGAGCCGCGAAACCGGCGATATCGCTGGCGCACTGCAACTCGCGTCTTCACTACAGCCGATCTGGTTTGGTCGGGGCCACATGTATGAGGGGTTGGCCTGGTTCGACTCGATCTTTGAACACAAAAACATCGAGCATCTTGTTGCACCCAAAGAGGTTTTAGCTCGGGCGGTTGCCAACAAGGTTATGCTCCACGCCATATTGGCCAGCAGTCCACCAGACGGCAGTGACCTCGTCACTCAAGCTCAACAAGCTCTGACCATGGCACGCGAGATAGGTGACTCTGCTGTTTTGGCTCGGGCGCTTACTGCCTGCGGCTTCAGCAGTGGCTATGACACGGAGGTGGCTCGGCCCTACTTTGCCGAGGCGGTTGAGCTCGCGCGAACGCAAGGTGATAAATGGACACTGAGCCAGATTCGGCTTTGGGGAGTTGTTGGATTCTGCGTGTCAGGTGACCCGGTTGCTTTGCGAGCAGCAGCTGAGGCGGCCGACGATCTCGCTCAAGAAATCGGGGATCGGTTCGTTTCGCTACAGTGTCGTTTGCTGCTCTCCATTGCACAGTTATGGCAGGGCGATATGGACGGAGCGATCGTACGATCGGGTGAAGTTGTTGCCGGTGCTGAAGCTGCCCACGATACAGTGACGAGAACTTTCGGTCTGTACGTCCAAACTCGGGCGCTGGTGCATCGCGACGTCAGCGCGGCCCTGGTTACGGCCGGCCTGGTCGTTGAAGCCGCAGCGGAATTAAGTGGGGTGTACCAAGGTATTGGTTATGCAGCAATGGTTTTTGCGGCGTTGGCTATGGGCGATGTTGCCGCGGCTGTCGAGGCCAGCGAGGCGTGCCGGCCGCACCTGGGTGCTGACCACGGCCTGGTAGCGATACACCTCGAACTCATGGCGGCGGTCGCTTTGGCAAGAGGCGATGTAATCGTGGCGCGACGCCTCGCCGACAATAGTGTTTCTGCGACCACTGGGTGGCATCAAATGGCGGCCTTGACAACGCGTGCGCGCATCGCTATGGCGCAGGGTGAACCAGAACTGGCACGAGCTGATATCCATGCTGCGCTTGCGTGCGGTGCCGACATCCAGGCGTCTCTGGGCATATCAGACAGCATGGAATTGTTAGCCGAGCTGATCAGCCAGGGTGACAACCATCGTCAAGCCGGGCGTCTTTTCGGTGCGGCGTCCGCGCAACGTGAGAAGACAGGTGAGGTCCGCTTCAAAGTCTGGGATGCAGGCTATGAGTCCGCAGTGGCGGTGCTTCGTGGCGCGATGGGCTGCAAGGATTTCGACTCCGCCTGGGCAGAGGGTGCTGCCATGCCCATCGACGACGCGATCACCTACGCACAGCGCGGGCGTGGCAACCGTAAACGACCGACCACTGGTTGGGAATCCCTAACCCCTGCCGAACACAATGTAATACGGCTCGTTAGCGAGGGGTTAGATACCAAAGATATCGCGGCACGGCTTTTCGTCTCCGTTCGAACCGTACATACCCATCTCACACGCATCTACTCTAAACTTGGCCTCACCTCCCGCGTCCAACTCGTGCAAGAAGCTGCGCGCCA

Protein Sequence 

>ML1753c_ML1753c_protein
GRHVFFGRDAETSTRWR_LSGFMSGGAAEIDRCTDGPPSRLHGDVVSG_RRRLGRAVRNTTR_GSGCNRTPGLCGVRSCRGSRRGATGCPRGKGKLSRNVCPC_RRHSVRIRPAAGPDRTSSVSYRSAHR_GSDIQR_CQ_CGFYDGAGCRVARFGMRGTNGVVIYHRRSRR_WAPR_YLAGGSWQSPIAGSGSASTCHAVVSP_SAQKSSRARYPDCPWRTKSSGAAHHFCWSRCADQRTARAVDRKTVVNAGRSRGSRKNAARVTGRR_GRRRV_W_AVVFRPSSGHRSRHLSDYGVRQSAPVHR_PSHADGVGQLRVPSRCVRECDDYAVGRLSVVDDFGDQS_ADRGGRRSHMAGFNAVSCRRSGRIIHRTSCLGSTRFQCYRWQPSDRDRDLSAP_RHAFGD_AGRCTDTYVIVN_DSRWFG_PVSAADWWCAYRGATSTDAPCLDGLVVCIADRKRAGLVSSLVGNFGDVRPQGGLCGWTR_S_GA_SGFRSADYAHRQVFGHS_RQTGWLAVPVAGNGAPVRDEEARRVQ_GRPCACPSPRSLHGTWGFAGYSGRHRPRAAC_AS_DRA_QSA_RIRMEPRNRRYRWRTATRVFTTADLVWSGPHV_GVGLVRLDL_TQKHRASCCTQRGFSSGGCQQGYAPRHIGQQSTRRQ_PRHSSSTSSDHGTRDR_LCCFGSGAYCLRLQQWL_HGGGSALLCRGG_ARANAR__MDTEPDSALGSCWILRVR_PGCFASSS_GGRRSRSRNRGSVRFATVSFAALHCTVMAGRYGRSDRTIG_SCCRC_SCPRYSDENFRSVRPNSGAGASRRQRGPGYGRPGR_SRSGIKWGVPRYWLCSNGFCGVGYGRCCRGCRGQRGVPAAPGC_PRPGSDTPRTHGGGRFGKRRCNRGATPRRQ_CFCDHWVASNGGLDNACAHRYGAG_TRTGTS_YPCCACVRCRHPGVSGHIRQHGIVSRADQPG_QPSSSRASFRCGVRAT_EDR_GPLQSLGCRL_VRSGGASWRDGLQGFRLRLGRGCCHAHRRRDHLRTARAWQP_TTDHWLGIPNPCRTQCNTAR_RGVRYQRYRGTAFRLRSNRTYPSHTHLL_TWPHLPRPTRARSCAP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML1753c with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

10 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML1753c

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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