uspA
mL1768
PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2143283 – 2144269
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1768_uspA_dna
CCCACTTTAATACCTCCATGACCAACACCGGCGACGATACAGAGCAAAGCGATGAAGTGGGGAGCATCTCCCGCTTGCGGGGGAGAAAGACACACAGGACCCGCGCCCTAACGAAGAACCACCCACGATCCATCGCTCTGGCCTACGCCCTGCTGGCCCCCAGCCTGTTCGGCGTGGTCACCTTCTTGCTGCTACCCATCATCGTGGTTATCTGGCTTAGCCTGTTCCGGTGGGACCTGTTGGGACCCCTGCACTATGTCGGCCTGGCCAACTGGCGGTCAGTGCTGACCGACCCCAATTTCGCCAATTCACTAATTGTCACAGCCGTCTTCGTGGCGATTGTGGTACCAACTCAGACGATGCTCGGCCTGCTTATCGCGACAATGCTGGCCCGCCAACTTCCGGGCACCGGCGTGTTTCGCACGCTATACGTGCTGCCGTGGATCTGCGCCCCTTTGGCAATAGCGGTGTTGTGGCGCTGGCTCCTTGCTCCCACCGACGGTGCGTTCAGCATGGTCCTAAGACATCGCATAGAATGGCTCTCCGATCCCAGTCTTGCGCTACCGGTCGTTTCAGCTGTCGTCGTCTGGACCAACGTCGGCTACGTCTCGCTGTCGTTCCTCGCCGGACTGCTGTCTATCCCAGAAGACATTAACGCTGCCGCGCGCACCGACGGTGCCGATGCCTGGCAGCGGTTCTGGCGCATCACTCTGCCGATGTTACGGCCGACGATGTTCTTTGTGCTGGTTACCGGAATAGTGAGCACAGCACAGGTTTTCGACACCGTCTATGCGCTGACTGACGGTGGTCCTAAGAGCCGCACCGACCTGGTGGCGCACCGCATCTATGCCGAGGCATTCGGCTCTGCGGCCATTGGGCGAGCATCGGTGATGGCAGTGTTATTATTCGTCGTCCTATTCGGCGTCACTGTTGTTCAACATTTGTACTTCCAGCGTCGGATCAGCTATGAGCTCACCTAGTCGCTTG

Protein Sequence 

>ML1768_UspA_protein
PTLIPP_PTPATIQSKAMKWGASPACGGERHTGPAP_RRTTHDPSLWPTPCWPPACSAWSPSCCYPSSWLSGLACSGGTCWDPCTMSAWPTGGQC_PTPISPIH_LSQPSSWRLWYQLRRCSACLSRQCWPANFRAPACFARYTCCRGSAPLWQ_RCCGAGSLLPPTVRSAWS_DIA_NGSPIPVLRYRSFQLSSSGPTSATSRCRSSPDCCLSQKTLTLPRAPTVPMPGSGSGASLCRCYGRRCSLCWLPE__AQHRFSTPSMR_LTVVLRAAPTWWRTASMPRHSALRPLGEHR_WQCYYSSSYSASLLFNICTSSVGSAMSSPSRL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding UspA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

5 proteins show strong predicted evidence for PPIs

12 show intermediate predicted evidence for PPIs

111 show weak predicted evidence for PPIs

View all pooled AlphaFold results for UspA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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