uspC
mL1770
PROBABLE PERIPLASMIC SUGAR-BINDING LIPOPROTEIN USPC
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2145172 – 2146512
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1770_uspC_dna
GGCCCCGCTATTCAACATTAGTTGCCGAAGCACTTGCGTTGGCCACCGTCCTGTTGACTGCTACAGCAATGCTGATGGGCTGGTCAGGAGGCCAGCTACGTGGCGGTAAGGTCGTCGTTACAATGCGCCTGTGGGCTGACCAGATTTCCACAGCATATAGTCAGTCGTTCCAGGCCTTTACCCGTACCCATCCCGATATCGAGGTGCACACCAATGTCGTTGCCTACTCGAAGTATTTCAATACCCTACGCACCGACGTAGCCGGCGGCAGCGCCGACGATATCTTTTGGCTATCAAGCGCTTACCTCGCAGCATATGCTGACAACGGTCGGTTGATAAACATTAGTAACAGCCTCGGACAGAGGGCCACTTCAGACTGGGAGCCAGCAGTGGTAGACCAATTCACCCGAGCCGGAGCGTTATGGGGTGTACCGCAGTTGACCGATGCCGGCATCGCTGTATTCTATAACGCCGACCTGCTCACTGCTGCCGGTATTGATCCGGTCCAGCTCAACCGCATGCAATGGACTTCTAACGATGACGACACCTTGCGCCCCTTACTGACTCAGCTCACCCTAGACACCAATGGACATGTCGCTAAAACACCAGGTTTCGATTCAAGACGAGTCCGTCAATGGGGGTATAATGCGGCCAACGACCCCCAGGCCATCTACCTTAACTACATCGGGTCAGCCGGTGGAGTATTCCAACGCGGCGACGAGTTCGCCTTCGATAACCCTTCGGCGGTCGAAGCCTTCCGATACCTAGTCGGTCTGATCAACAACGATCACGTGGCACCGCCGGCCTCAGAAACCAACAACAACGGCGATTTCTCGCGCAACCAATTTTTGTCTGGCAGGATGGCACTCTTCCAGTCCGGCACCTACAACTTGGCACTAATAGCCCGCGAGGCCCGGTTCCACTGGGGTATCGCAATGATGCCGACCGGCCCGCAGGGACGAGTGAGTGTTACCAATGGTATTGCCGTAGCTGGTAATTCAGCAACCAAGCATCCGGATGCGGTGCGTCAAGTATTGGCCTGGATGGGCAGCAGGGAGGGCAACGCGTACCTGGGGCGTCACGGTGCCGCCGTCCCAGCAGTGCGGTCAGCTCAGTCGGTCTACTTCGACTACTGGGCCGCAAAGGGCATCGACGTCACACCCTTTTTCTCGGTGCTGGACGGCCCTCACATTCCGGCTCCGGGCGGCGCTGGCTTTCCCGCCGGAGACGACGCGTTGCAAAGCTATTTCGACGAAATGTTCCTAGGTCACGGTGATGTCGAGAAAATCCTGTGTCAAGCTCAAGCGGCAGCGAACACCGCAGCTCACCGCTAGCCAGAAA

Protein Sequence 

>ML1770_UspC_protein
GPAIQH_LPKHLRWPPSC_LLQQC_WAGQEASYVAVRSSLQCACGLTRFPQHIVSRSRPLPVPIPISRCTPMSLPTRSISIPYAPT_PAAAPTISFGYQALTSQHMLTTVG__TLVTASDRGPLQTGSQQW_TNSPEPERYGVYRS_PMPASLYSITPTCSLLPVLIRSSSTACNGLLTMTTPCAPY_LSSP_TPMDMSLKHQVSIQDESVNGGIMRPTTPRPSTLTTSGQPVEYSNAATSSPSITLRRSKPSDT_SV_STTITWHRRPQKPTTTAISRATNFCLAGWHSSSPAPTTWH__PARPGSTGVSQ_CRPARRDE_VLPMVLP_LVIQQPSIRMRCVKYWPGWAAGRATRTWGVTVPPSQQCGQLSRSTSTTGPQRASTSHPFSRCWTALTFRLRAALAFPPETTRCKAISTKCS_VTVMSRKSCVKLKRQRTPQLTASQK

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding UspC with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

49 show weak predicted evidence for PPIs

View all pooled AlphaFold results for UspC

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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