hsp18
mL1795
18 KDA antigen Hsp18 (HSP 16.7)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2174304 – 2174750
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1795_hsp18_dna
TGCGTACTGACCCGTTCCGTGAACTGGACCGCTTCGCCGAGCAAGTGTTAGGTACGTCTGCCCGCCCAGCAGTAATGCCCATGGACGCTTGGCGTGAGGGCGAAGAATTCGTCGTCGAGTTCGACCTTCCTGGCATCAAAGCCGATTCACTGGACATTGACATCGAACGCAACGTAGTCACCGTGCGGGCCGAGCGCCCAGGCGTCGACCCCGATCGGGAAATGCTTGCTGCCGAGCGGCCACGCGGTGTGTTCAATCGTCAGCTGGTTCTCGGCGAAAACCTCGACACCGAACGGATCTTGGCTTCCTACCAAGAAGGTGTCCTGAAGTTGTCGATACCAGTAGCCGAAAGGGCTAAACCGCGCAAGATCTCCGTTGATCGTGGCAACAACGGACACCAGACCATAAACAAAACCGCACACGAAATCATAGATGCCTAATCGACTG

Protein Sequence 

>ML1795_Hsp18_protein
CVLTRSVNWTASPSKC_VRLPAQQ_CPWTLGVRAKNSSSSSTFLASKPIHWTLTSNAT_SPCGPSAQASTPIGKCLLPSGHAVCSIVSWFSAKTSTPNGSWLPTKKVS_SCRYQ_PKGLNRARSPLIVATTDTRP_TKPHTKS_MPNRL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Hsp18 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

21 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Hsp18

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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