mutA
mL1800c
PROBABLE METHYLMALONYL-CoA MUTASE SMALL SUBUNIT MUTA (MCM)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2180192 – 2182102
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1800c_mutA_dna
GCAGTCGGTGTTCGTAGATGTACCCGAGTTCGCCGAACTGGAACAGATTCGCGGGCGGTGGCGACGTGCGGTCGCTGGTGTGCTCTCGAGGAGCATGCGGAGAGACCCTGCCACGTTTGGGGATCAGCCTGAGCGGCTACTGGACACCGCGACCTACGACGGGTTCGCCATCCGGCCGCTGTATACCGTGTTCGACGAGTTGCCGGAATCGTCGCTGCCAGGAGAGTGGCCTTACCGCCGCGGTGGCGATGCGTTACGCGATGTTCATTCCGGCTGGAAGGTCACCGAAGTGTTTCCGGTCGACCCGGCAACCGCAGGGGTGGCTGCCGACGAGGGCACGGCTAGCAACGCTACAATATTGGCTGCGCTAGCAGAGGGAGTCAGCGCGCTGCGAATCCGGGTGGGCCAGTCCGGGGTAGCGCCTGGGCAGCTGGACAGCCTGCTTCTCGGTGTGTACGTGGACTTGGTCCCGGTGATTCTTGACGCGGGCGCTGACTACGTCGAAGCCTGTGATGCGGTGTTGGCCCTGCTGGCCAGGCTGGACTCGAGTCGGCGCACAATGCTATCGATCGATCTGGGTGCCGACCCGCTGACTGCGTCGCTGAGCGGTCGTCCTGCCCCGTCGATCGACCAGGTGGTTGCAGTCGCAGCACGGGTCGCCGGCGACCGTGGCGTGCGGGCGATCACCGTCGACGGGCCTGCTTTCCACAATTTGGGGGCCAGCGCGACATGGGAGCTCGCCGCTGCGATTGCGGCTGCGGTGACCTACCTTCGGGTGCTCACAGAATCCAAGATGCCGGTCAGCGAGGCGCTACGGCAAATCAGTTTTCGGCTAGCTGCCGACGACGATCAGTTTTTGACCATCGCTAAAATACGCGCCGTGCGTCAACTGTGGGCGCGTATCGCAGAAGTCGCGGGGGACCCCGAAGGCGGCGCGGCAGTTGTGCACGCGGAAACGTCGCTGCCGATGATGACTCAGCGCGACCCGTGGGTGAACATGCTGCGCGGCACGCTGGCCGCGTTTGGTGCAGGCGTTGGTGGTGCCGACACCGTGTTGGTGTTCCCGTTCGATGTGGCGATTCCCGGTGGCTTTCTTGGCATGGCGGCTAGCTTCGCGCGTAGGATTGCCCGTAACACCCAGCTGCTGCTGTTGGAAGAGTCACACGTTGGCCGGGTGTTGGATCCGGCCGGAGGGTCCTGGTTCGTCGAGAACCTCACCGAACAACTGGCTCAGCAGGCCTGGCAGCATTTTCAGGCTATCGAGACCTACGGTGGATTTGTCGATGCCGGTGACTACCTTGCCGGCCAGATCCACGAAACAGCCGCACGCCGTACCGACGACATCGCGCATCGCCGTACCGCGATAACCGGTGTCAACGAATATCCGAACTTAGCTGAGCCTGCTCTGCTGCACGGCGGTTCGCCTGTTGTGGCGACTGCTGCGGGAAACCTGCTGCGCTACGCTGCCGGTTTCGAAGCGCTGCGGGATCGTTCGGATGCTTATCTGGCCCGCACCGGTGCACGTCCGCAGGTGCTGTTGCTGCCGCTGGGCCCGCTGGCTGAGCACAACATTCGGGCGACGTTTGCGACGAATCTGCTGGCTTCGGGCGGCATAGCGGCGATCAACCTAGGATCAGTGGACGCACCGGGTGTCGTGCAAGCCGTCGCGCAGGCTGGTTTCATGGCCGGGTCGTCGATGGTGGTGGTTATCTGTGGCACAGACTTGCGCTATCGGGATGAGGCCGCAGATGTGGTGGAGGCGGCGCGAGGCGCCGGGGTGTCGTGGGTCTACCTGGCGGGACCTGAGAAAGCGCTGGGTGATATCAACAACGCAAAGAGTCGGCCAGATGAATATATAACTGCGAAAATTAATGCGGTCGAAGCTCTTTCAAATCTGCTCACTCGATTGGG

Protein Sequence 

>ML1800c_MutA_protein
AVGVRRCTRVRRTGTDSRAVATCGRWCALEEHAERPCHVWGSA_AATGHRDLRRVRHPAAVYRVRRVAGIVAARRVALPPRWRCVTRCSFRLEGHRSVSGRPGNRRGGCRRGHG_QRYNIGCASRGSQRAANPGGPVRGSAWAAGQPASRCVRGLGPGDS_RGR_LRRSL_CGVGPAGQAGLESAHNAIDRSGCRPADCVAERSSCPVDRPGGCSRSTGRRRPWRAGDHRRRACFPQFGGQRDMGARRCDCGCGDLPSGAHRIQDAGQRGATANQFSASCRRRSVFDHR_NTRRASTVGAYRRSRGGPRRRRGSCARGNVAADDDSARPVGEHAARHAGRVWCRRWWCRHRVGVPVRCGDSRWLSWHGG_LRA_DCP_HPAAAVGRVTRWPGVGSGRRVLVRREPHRTTGSAGLAAFSGYRDLRWICRCR_LPCRPDPRNSRTPYRRHRASPYRDNRCQRISELS_ACSAARRFACCGDCCGKPAALRCRFRSAAGSFGCLSGPHRCTSAGAVAAAGPAG_AQHSGDVCDESAGFGRHSGDQPRISGRTGCRASRRAGWFHGRVVDGGGYLWHRLALSG_GRRCGGGGARRRGVVGLPGGT_ESAG_YQQRKESAR_IYNCEN_CGRSSFKSAHSIG

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MutA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

5 proteins show strong predicted evidence for PPIs

23 show intermediate predicted evidence for PPIs

102 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MutA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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