secY
mL1833c
PROBABLE PREPROTEIN TRANSLOCASE SECY
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2220763 – 2222079
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1833c_secY_dna
AGGAAGAGTGCTCTCGGCTTTCATCTCGTCGCTGCGGACAGTCGATTTAAGGCGGAAGATCCTTTTCACGCTGGGCATCCTCGTGCTCTATCGCGTCAGTGCGGCACTGCCCTCTCCGGGCGTCAACTACCGGCACGTGCAGCAATGCATTCAAGAGGCCACCGCCGGCGAAGCCGGGGAAATTTACTCGCTGATTAACTTGTTCTCCGGTGGTGCGCTGCTAAAGCTCACGGTAGGGGTGATGCCCTATATCACCGCCAGTATCATTGTGCAGTTGCTGACCGTGGTGATCCCGCGCTTTGAAGAATTACGCAAAGAGGGTCAAGCAGGCCAAGCGAAAATGACCCAATACACCCGCTATCTGGCTATCGCACTAGCCGTCCTGCAAGCCACCAGCATCGTGGCGCTGGCGGCCAACGGTGGACTGCTGCAGGGTTGCCAGGAGGACATCATCTCCGACCAGAGCATCTTCAGTCTGGTCGTCATCGTGCTGGTGATGACGGGCGGTGCGGCGCTGGTGATGTGGATGGGTGAGTTGATCACCGAACGTGGTATCGGCAATGGCATGTCGTTATTGATCTTCGTCGGTATCGCTGCCCGCATTCCCGCCGAGGGCAAACAGATCCTAGATAGCCGGGGTGGGGTCATCTTTGCCGCTGTTTGCCTGGCCGCACTGGTCATCATCGTTGGCGTGGTCTTCGTTGAGCAGGGCCAGCGCCGAATCCCGGTGCAATACGCTAAGCGCATGGTGGGTCGGCGGATGTATGGCGGGACCTCAACATACCTGCCGCTCAAGGTCAATCAGGCCGGCGTTATTCCGGTAATCTTCGCGTCGTCGTTAATCTACATTCCACATCTGATCACCCAGCTGGTCCGCAGCGGCAGCGGTGGTGTGGGCAAGAGCTGGTGGGACAAATTCGTCGGCACCTACCTATCGGATCCGGCCGATCCCGTTTATATCAACATATACTTCGGGCTTATCATCTTCTTCACCTACTTCTATGTATCGGTAACATTCAATCCCGACGAACGTGCCGACGAGATGAAGAAGTTCGGTGGTTTCATTCCTGGCATTCGACCGGGACGGCCGACGGCGGACTATTTGCGTTATGTGCTAAGCCGAATTACGTTGCCGGGATCGATCTATCTTGGAGCGATCGCGGTGTTGCCCAATCTATTCCTGCAGATCGGCAATGGCGGCGAGGTCCAGAATTTACCGTTCGGGGGAACCGCTGTGTTGATCATGATCGGTGTTGGCTTGGATACGGTCAAGCAGATCGAGAGTCAGCTGATGCAACGCAACTATGAAGGGTTCCT

Protein Sequence 

>ML1833c_SecY_protein
RKSALGFHLVAADSRFKAEDPFHAGHPRALSRQCGTALSGRQLPARAAMHSRGHRRRSRGNLLAD_LVLRWCAAKAHGRGDALYHRQYHCAVADRGDPAL_RITQRGSSRPSENDPIHPLSGYRTSRPASHQHRGAGGQRWTAAGLPGGHHLRPEHLQSGRHRAGDDGRCGAGDVDG_VDHRTWYRQWHVVIDLRRYRCPHSRRGQTDPR_PGWGHLCRCLPGRTGHHRWRGLR_AGPAPNPGAIR_AHGGSADVWRDLNIPAAQGQSGRRYSGNLRVVVNLHSTSDHPAGPQRQRWCGQELVGQIRRHLPIGSGRSRLYQHILRAYHLLHLLLCIGNIQSRRTCRRDEEVRWFHSWHSTGTADGGLFALCAKPNYVAGIDLSWSDRGVAQSIPADRQWRRGPEFTVRGNRCVDHDRCWLGYGQADRESADATQL_RVP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SecY with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

5 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

120 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SecY

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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