mkl
mL1892c
POSSIBLE RIBONUCLEOTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MKL
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2277267 – 2278283
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1892c_mkl_dna
CGGAAGGATGCCCATGGGCGTTGCGATCGAAGTTAAGGGACTAACCAAGTCTTTTGGATCTTCGAGGATTTGGGAAGACGTCACGCTTGACATTCCCGCAGGAGAGGTCAGTGTGTTACTCGGGCCGTCGGGTACCGGCAAATCAGTGTTCTTGAAGTCCCTCATCGGTCTGTTGCGGCCGGAACGTGGCTCGATCCTAATTGATGGTACGGACATCATCGAATGTTCAGCCAAGGAACTCTACGAGATCCGCACACTGTTCGGCGTGCTATTCCAGGACGGCGCGCTGTTCGGCTCGATGAACCTCTACGACAACACTGCGTTCCCATTGCGTGAGCACACCAAGAAAAAGGAAAGCGAGATCCGTGACATCGTCATGGAGAAGCTGCAGCTGGTCGGCCTTGGTGGGGACGAGAAGAAGTTCCCCGGCGAGATCTCCGGCGGTATGCGCAAGCGTGCCGGTCTAGCGCGAGCCTTGGTTCTTGACCCGCAGATCATTCTGTGCGACGAGCCCGACTCGGGTCTGGACCCGGTCCGTACCGCTTACCTGAGTCAGCTGATCATGGACATCAATGCCCAGATTGATGCGACCATCCTAATCGTGACGCACAACGTCAACATCGCCCGCACTGTGCCCGACAACATGGGCATGTTGTTCCGCAAGCATCTGGTAATGTTCGGACCCCGTGAGGTGCTGCTAACCAGCGACGAGCCGGTTGTACGGCAATTCCTCAACGGCCGTCGTATCGGCCCGATTGGGATGTCCGAGGAGAAGGACGAGTCCACCATGGCTGAAGAGGCAGCTTTGCTCGAAGCAGGTCACTACGCGGGTGGCGCCGAGGAAGTCGAGGGTGTGCCGCCGCAGATCACCGTGACACCGGGGATGCCGAAGCGCAAAGCGGTCGCACGCCGCCAGGCCCGGGTGCGGGCGATGTTGCCTACACTGCCCAAGGGTGCCCAGGCGGCGATCCTCGATGATCTCGAGGGCGCCCACAATTACCAAGCGCACGAATTCGG

Protein Sequence 

>ML1892c_Mkl_protein
RKDAHGRCDRS_GTNQVFWIFEDLGRRHA_HSRRRGQCVTRAVGYRQISVLEVPHRSVAAGTWLDPN_WYGHHRMFSQGTLRDPHTVRRAIPGRRAVRLDEPLRQHCVPIA_AHQEKGKRDP_HRHGEAAAGRPWWGREEVPRRDLRRYAQACRSSASLGS_PADHSVRRARLGSGPGPYRLPESADHGHQCPD_CDHPNRDAQRQHRPHCARQHGHVVPQASGNVRTP_GAANQRRAGCTAIPQRPSYRPDWDVRGEGRVHHG_RGSFARSRSLRGWRRGSRGCAAADHRDTGDAEAQSGRTPPGPGAGDVAYTAQGCPGGDPR_SRGRPQLPSARIR

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Mkl with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

15 show intermediate predicted evidence for PPIs

45 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Mkl

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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