mmaA4
mL1903
METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2287638 – 2288534
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1903_mmaA4_dna
AGCAACCGACTGGCCCGACAAAAACGCGGACGCGCTCCGAAGATATCCAAGCGCACTACGATCTTTCGAACGAATTCTTCGCACTGTTCCAGGACCCCACCCGCACCTACAGCTGCGCCTATTTCGAGCCACCAGACCTCACGCTCGAAGAAGCCCAGTACGCCAAGATCGACCTCAACCTGAACAAGCTGGACCTCAAGCCGGGAATGACTCTGTTGGACATCGGCTGCGGTTGGGGCACCACCATGCGGCGCGCCGTTGAGAAGTATGATGTCAAAGTTATCGGCTTGACTTTGTCCAAGAATCAGCACGCACGTTGTGAGCAAGTGCTAACCGCCCTCGAGAGCAACCGTTCACGTCAAGTGCGGCTGCAAGGCTGGGAGGATTTCACCGAGCCGGTCGACCGGATCGTGTCGATCGAGGCCTTCGAACACTTCGGGCACGAGAACTACGACGACTTCTTCAAGCGGTGTTTCAACATCATGCCCTCCGACGGTCGGATGACGGTCCAAAGTAGTGTCAGCTACCACCCCTTCGACATGGCTGCCAGGGGTAAGAAGCTCAGCTTCGAAACGGCTCGCTTCATCAAGTTCATCATCACCGAGATATTTCCAGGTGGGCGGCTGCCATCGACCAAGATGATGGTTGAACACGGCGAGAAGGCAGGATTCACCGTCTCCGAACCGCTGTCGCTGCAATCGCACTATGTCAAGACACTGCGAATCTGGGGCGACACCCTAGAATCCAACCGGGCAAAGGCCATCGAAGTCACCTCTGAAGCGGTCTACAACCGGTACATGAAGTACCTGCGCGGCTGCGCGCACTACTTCTCCGACGAGATGCTGGACTGTAGCCTAGTGACCTACCTCAAGCCGGGCGCCTTAGACTAGTGCCGCC

Protein Sequence 

>ML1903_MmaA4_protein
SNRLARQKRGRAPKISKRTTIFRTNSSHCSRTPPAPTAAPISSHQTSRSKKPSTPRSTST_TSWTSSRE_LCWTSAAVGAPPCGAPLRSMMSKLSA_LCPRISTHVVSKC_PPSRATVHVKCGCKAGRISPSRSTGSCRSRPSNTSGTRTTTTSSSGVSTSCPPTVG_RSKVVSATTPSTWLPGVRSSASKRLASSSSSSPRYFQVGGCHRPR_WLNTARRQDSPSPNRCRCNRTMSRHCESGATP_NPTGQRPSKSPLKRSTTGT_STCAAARTTSPTRCWTVA__PTSSRAP_TSAA

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding MmaA4 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

32 show weak predicted evidence for PPIs

View all pooled AlphaFold results for MmaA4

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.