xseA
mL1940
PROBABLE EXODEOXYRIBONUCLEASE VII (LARGE SUBUNIT) XSEA (EXONUCLEASE VII LARGE SUBUNIT)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2326360 – 2327646
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1940_xseA_dna
AAGCGGTGCCGACTGACTCAGTCGACTCGAAAGCCAGTTCACAGGTAAATTCGGCCGAGAACCCGTTCCCAGTTCGCGCGGTGGCGCTCCGGATCGCGGGATGGATCGACAAGCTGGGCACTGTTTGGGTAGAGGGACAATTGGCGCAAATCACCATGCGGCCCAACGCTAAGACCGTGTTCATGGTCTTACGTGACCCGGCTGCCGACATATCGCTGATTGTGACTTGCTCGCGCGACTTTGTGCTACGCGCGCCGGTGAAACTAGCCGAAGGCATTCAGGTAGTGGTATGCGGCAAACCCTCATTCTACATCGGGCGCGGAACATTTTCTTTGCGCCTCAGCGATATTCGCGCAGTCGGCATCGGAGAGCTGCTAGTACGCATCGATCGGCTACGCCGACTGTTGGACTCTGAGGGGCTCTTTGACCCACGGCTTAAACGGCCGATACCCTTCCTGCCCAACATGATCGGGATCATCACTGGCCGGGCCAGCGCTGCCGAACGCGATGTAACAACCGTGGCTAGCGCGCGCTGGCCTGCGGCGCGTTTCGCTATCCGCAACACCGCTGTCCAGGGGCCCAACGCGGTGAGCCAGATTGTCGAGGCGTTGCGGGAACTTGATCGCAACGTTGATGTCGAGGTGATCGTGGTTGCCCGAGGTGGTGGCAGCGTCGAGGACCTGCTGACGTTTTCCGATGAAACGCTGTGCCGCGCGATCGCAGCGTGCCGCACGCCGGTGATCAGCGCAGTCGGTCACGAACCCGACAACCCGCTATGCGATCTGGTCGCCGATCTGCGCGCCGCCACGCCCACCGACGCCGCCAAGAAAGTGGTCCCGGATGCCGCTGTCGAGCAGCGACTGATCGAGGACTTGCAGCGGCGCAGCGCGCAGGCACTCCGCAATTGGGTATCCCGCGAGCAGCGGACGCTAGTCCAACTACGCAGTCGCCCAGTGCTGGCTGAACCGCTGCGGACGCTGACGACGCGCTCCGAAGAAATTCACCGCGCCCAGTCGGCGATTCGCCGCGAGATCATTCGGCTGGTCACCACCGAGACCGAGCGGGTCGGTCATCTGGCCACGCAGCTAGCCACATTGGGCCCGGCAGCCACGTTGGCGCGCGGCTATGCCATAGTGCAAGCCTTGGAAGACGGGACGCAAACCGTTACTGCGGCAGTGCTGCGGTCAGTCGATGATGCACCCACAGGCACCAGACTGCGGGTGCGGGTCTCTGACGGCGCCATAGTGGCAGTTAGTGAAGGACGGGCCGATGGTCCCTGAAGACGAT

Protein Sequence 

>ML1940_XseA_protein
KRCRLTQSTRKPVHR_IRPRTRSQFARWRSGSRDGSTSWALFG_RDNWRKSPCGPTLRPCSWSYVTRLPTYR_L_LARATLCYARR_N_PKAFR_WYAANPHSTSGAEHFLCASAIFAQSASESC_YASIGYADCWTLRGSLTHGLNGRYPSCPT_SGSSLAGPALPNAM_QPWLARAGLRRVSLSATPLSRGPTR_ARLSRRCGNLIATLMSR_SWLPEVVAASRTC_RFPMKRCAARSQRAARR_SAQSVTNPTTRYAIWSPICAPPRPPTPPRKWSRMPLSSSD_SRTCSGAARRHSAIGYPASSGR_SNYAVAQCWLNRCGR_RRAPKKFTAPSRRFAARSFGWSPPRPSGSVIWPRS_PHWARQPRWRAAMP_CKPWKTGRKPLLRQCCGQSMMHPQAPDCGCGSLTAP_WQLVKDGPMVPEDD

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding XseA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

24 show weak predicted evidence for PPIs

View all pooled AlphaFold results for XseA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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