desA2
mL1952c
POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2339277 – 2340104
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1952c_desA2_dna
TTACCTTATGGCACAGAAACCTGTACCTAACGCATTGATCCTTCAGCTTGAGCCTGTGGTGAAAGACAACATGGCTCGACACTTCGCAAACGAGGAACTCTGGTTCGCCCACGACTACGTACCGTTCGACCGGGGTGAAAACTTTGCCTTCCTTGGCGGCCGCGATTGGGATCCGTCCCAGGCGACGTTGGCCAAGGCCGTCACGGACGCCTGCGAGATCCTGCTGATTCTTAAAGACAACCTCGCCGGTTATCACCGCGAACTCGTCGAGCATTTCATTCTCGAAGGTTGGTGGGGTCGTTGGCTCGGCAGGTGGACCGCGGAGGAGCATCTGCATGCCATCGCATTGCGCGAATACTTGGTAGTGACCCGAGAAGTCGATCCGGTAGCCAACGAACAGGTTCGAGTCGAGCACGTGATGAAGGGCTACCGCGTCAACTCGTACACGCAGATCGAAACCTTGGTCTACATGGCGTTCCTGGAGCGCAGTTACGCCTTTTTCTGCGGCAGCTTGGCAGCGCAGATTAAGGAGCCCGCTTTGTTCGGACTGATCAACCAGATCGTCAAAGACGAAGTACGTCACGAGGAGTTCTTCGCCAACCTCGTCGCGCACTGTCTGGAGTGCAATCGCGACGAGACGGTCGCCGCGATTGCCGCTCGTGCAGCCGGTCTAGATGTCCTCGGTGCTGACATTGACGCTTACCACGACAAAGTAGAAAACATCTCCGCTGCTGGTATTTTCGGATCTGTCGAACTGCGGCAAGTGATCTCCGACCGCATCACCGCATGGGGTTTGATAAACGAACCGCAACTGGCGCAATTCGTCAC

Protein Sequence 

>ML1952c_DesA2_protein
LPYGTETCT_RIDPSA_ACGERQHGSTLRKRGTLVRPRLRTVRPG_KLCLPWRPRLGSVPGDVGQGRHGRLRDPADS_RQPRRLSPRTRRAFHSRRLVGSLARQVDRGGASACHRIARILGSDPRSRSGSQRTGSSRARDEGLPRQLVHADRNLGLHGVPGAQLRLFLRQLGSAD_GARFVRTDQPDRQRRSTSRGVLRQPRRALSGVQSRRDGRRDCRSCSRSRCPRC_H_RLPRQSRKHLRCWYFRICRTAASDLRPHHRMGFDKRTATGAIRH

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding DesA2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

9 show weak predicted evidence for PPIs

View all pooled AlphaFold results for DesA2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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