truA
mL1955c
PROBABLE TRNA PSEUDOURIDINE SYNTHASE A TRUA (PSEUDOURIDYLATE SYNTHASE I) (PSEUDOURIDINE SYNTHASE I) (URACIL HYDROLYASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2343336 – 2344085
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1955c_truA_dna
CGCTGGCGTGCTGGATGAAGCTTTCACGACTGTTTTCCGCACACCGGTGCGACTGCGCGCTGCCGGGCGCACCGACACAGGCGTACACGCCACCGGGCAGGTGGCCCATGTAGATATTCCCGGAACTGCCTTGTCGAAAGCCAATCCACGCTCACCACATACCGGTGATCCGGAATTCCTGCCTCTGCTGCGGCGTCTCAGCCGGCTCCTGCCTGTTGACGTCCGAGTTCTCGATATAGCCTGTGCACCAGTAGGATTCGATGCCAGGTTTTCAGCCTTGCGGCGGCATTATCGGTATCGGTTATCGACGGCACCCTACGGAGTTCAGCCGAACCAGGCGCGCTACGTCACTGCTTGGCCTCGTGAACTGGATCTGGATTCTATGTCCGCTGCATCGCGAGATTTGTTGGGGCTACGTGACTTTGCGGTGTTTTGCCGTCATCGCCACGGTGCTACCACCATTCGTGAGTTACAGCGGCTGGAATGGTCGCGAGAAGGATATTTGATCACCGCCCATATCACTGCTGATGCATTTTGCTGGTCGATGGTGCGGTCGCTGATCGGAGCGTTGCTGGCTGTGGGTGATCACCGACGCACCATCGGCTGGTGTGGTGAGTTGCTCACAAAGGCAAGCCGGTCCAGCGACTTCACAACTGCGCCGGCACATGGCTTGACGTTTATTCGCGTGGATTATCCACCTGACGATGAGCTGGCTGAGCGGGCCGTGATTACCCGGGATCTGCGATCATC

Protein Sequence 

>ML1955c_TruA_protein
RWRAG_SFHDCFPHTGATARCRAHRHRRTRHRAGGPCRYSRNCLVESQSTLTTYR_SGIPASAAASQPAPAC_RPSSRYSLCTSRIRCQVFSLAAALSVSVIDGTLRSSAEPGALRHCLAS_TGSGFYVRCIARFVGAT_LCGVLPSSPRCYHHS_VTAAGMVARRIFDHRPYHC_CILLVDGAVADRSVAGCG_SPTHHRLVW_VAHKGKPVQRLHNCAGTWLDVYSRGLST_R_AG_AGRDYPGSAII

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding TruA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

17 show weak predicted evidence for PPIs

View all pooled AlphaFold results for TruA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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