ML1974
mL1974
POSSIBLE CONSERVED PERMEASE
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2358459 – 2360177
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL1974_ML1974_dna
TAAGCGCTGACGTCAGTTGCATTGAGATTGTGGACATCAATTGTTCCGAGCTGCGCAACGATCGACGCATACCACCACAGTTAGCACTCTTCTGCACGAACGCCGCCAATAAGGCAGAATCGGCTGTGACGAGTCATGGTCAACTACCGATTATGGCAAACCGTCGCTGGGCTCCGCATACTAGAAGACAGAGTGGTCGCGCTACCTCAACTTGCTCGTCACTCATGAGATTCTCAGCAAGTGAATCTAGAGCACATTCAAGGTTTGAGTGCTACACCCTTGTGAGATGGTCGATCCGCGGACAAGGAGGACGTGCGATTAGCAAGCTTGGTTTCTGGAGTGTTGTTATGCTTGGTATCAACTCGATAATCGGAGCGGGTATCTTCATGACTCCCGGTGAAGTGATCAAGATTGCTGGACCGTTCGCCCCGATCGCATATACTCTTGCAGGAATTTTCGCAGCCGTACTGGCAATCGTCTTTGCGACAGCGGCCAAGTATGTCAAGACGAACGGTTCCTCCTATGCCTACACTACAGCTGCATTTGGGCACCGAATCGGTATCTATGTCGGTGTCACCCATGCAATTACCGCCTCTATCGCATGGGGGGTTCTGGCTTCCTCGTTTGTCTCAACACTGTTGAGAGTGGCTTTCCCCGAAAAGATTTGGGCCGATAACGACGAACTTATCAGCGTGAAGACACTCACGTTCCTCGTCTTTATCGCAGTTTTATTAGCAATAAACATATTTGGAAACCTCGTGATCCGGTGGGCCAACGGAATCTCAGCGCTGGGAAAGATTTTCGCGCTATCAGTCTTCATCGCCGGAGGATTGTGGACAATCATAACACAGCACGTGAACAACTACGTGACGTCCCGATCAGCGTACCAACCCACAACGTACTCGTTGCTCGGTGTCACCGAGATCGGTAAGAGCACCGCAGCGAGTATGACACTCGCAACGATCGTCGCGTTGTACGCATTCACTGGTTTCGAATCTATCGCTAACGCCGCAGAAGAGATGAACACACCGGACCGCACCCTTCCCAAAGCCATACCACTGACAATCCTCACTGTCGGCGTCATCTATATACTCGCCTTAGTCGTCGCAATGCTGCTGGGATCGGACAAAATTGTCGCTACTAACCACACCGTGAAATTGGCCGCGGCCGTCGGAAACAATACTTTCCGCACCATCATCGTTGTTGGAGCTTTAGTATCTATGTTTGGCATCAACGTAGCGGCATCGTTCGGTGCTCCCCGGCTCTGGACCGCGTTGTCGGACGGTAGAATTCTGCCAACAAGGCTGTCGAGCAAGAATCGATTCGGCGTTCCCATAGTTGCCTTTGGAATCACGGCGTTTCTAACGCTCGCCTTCCCACTGTCGCTTCGATTCGACAGCCTGAACCTCACCGGTCTGGCAGTGATCGCTCGATTCATCCAATTCATAATCGTACCGATCGCGCTCTTCGCGTTGGCACGTTCCCGGACAACGAATTCTGTATATGTGAAGCGAAATGTGTTTACTGACAAGGTGTTGCCGATCACTGCAGTTGTGGTCTCGGCCGGGCTGATGGTATCGTTTGACTACCGGTCCATTTTTCTCACGCGCGGAGGCCCTAATTACTTTTCGATTTCTTTGATTGCGATTACGTTTATCGGCATACCGGCAGTCGCCTACCTTCACTATTACAGAACCAGTGGAATTAAGTGACCCAACG

Protein Sequence 

>ML1974_ML1974_protein
ALTSVALRLWTSIVPSCATIDAYHHS_HSSARTPPIRQNRL_RVMVNYRLWQTVAGLRILEDRVVALPQLARHS_DSQQVNLEHIQGLSATPL_DGRSADKEDVRLASLVSGVLLCLVSTR_SERVSS_LPVK_SRLLDRSPRSHILLQEFSQPYWQSSLRQRPSMSRRTVPPMPTLQLHLGTESVSMSVSPMQLPPLSHGGFWLPRLSQHC_EWLSPKRFGPITTNLSA_RHSRSSSLSQFY_Q_TYLETS_SGGPTESQRWERFSRYQSSSPEDCGQS_HST_TTT_RPDQRTNPQRTRCSVSPRSVRAPQRV_HSQRSSRCTHSLVSNLSLTPQKR_THRTAPFPKPYH_QSSLSASSIYSP_SSQCCWDRTKLSLLTTP_NWPRPSETILSAPSSLLEL_YLCLAST_RHRSVLPGSGPRCRTVEFCQQGCRARIDSAFP_LPLESRRF_RSPSHCRFDSTA_TSPVWQ_SLDSSNS_SYRSRSSRWHVPGQRILYM_SEMCLLTRCCRSLQLWSRPG_WYRLTTGPFFSRAEALITFRFL_LRLRLSAYRQSPTFTITEPVELSDPT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML1974 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

17 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML1974

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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