glcB
mL2069
PROBABLE MALATE SYNTHASE G GLCB
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2458003 – 2460198
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2069_glcB_dna
ATCGCGTGTCGGCGGGGAATTTGCGCGTCGCCCGTGTGCTTTACGACTTCGTCAACAACGAAGCCCTGCCTGGCACCGACATCAACCCAAACAGCTTCTGGTCGGGCGTCGCCAAGGTCGTCGCCGACCTCACCCCGCAAAACCAAAGTTTGCTGAACTCCCGCGATGAGCTGCAGGCCCAGATTGACAAATGGCACCGCCATCGTGTGATCGAGCCATTCGACGTGGATGCTTATCGGCAGTTCCTCATCGATATCGGCTATCTGCTGCCTGAACCCGATGACTTCACCATCAGCACCTCAGGAGTAGACGACGAGATCACCATGACCGCCGGCCCGCAGCTGGTGGTGCCGGTACTTAACGCACGGTTCGCACTCAACGCCGCCAACGCCCGCTGGGGCTCCCTTTACGACGCTCTATATGGCACCGACACCATACCGGAAACCGAGGGAGCCGAAAAGGGCTCTGAGTACAACAAGATTCGCGGCGACAAGGTGATCGCCTACGCACGCAAGTTTATGGATCAGGCCGTCCCGCTGGCTTCTGACTCATGGACTAACGCTACGGGAGTGAGCATCTTCGACGGCCAGCTTCAGATCGCCATCGGCACGAATTCCACCGGATTAGCCAGTCCCGAAAAGTTTGTCGGCTACAATCGCCAGTTGCGATCCTCCAACTGGTCGGTGCTGTTGGCCAATCACGGCCTGCACATCGAGGTCTTGATCGACCCGGAATCACCAATAGGCAAGACTGACCCCGTCGGCATCAAGGATGTGATCCTGGAATCGGCCATCACCACGATCATGGACTTCGAAGACTCAGTCACTGCCGTCGACGCCGACGACAAGGTACGCGGCTACCGCAACTGGCTCGGCCTGAACAAAGGTGACTTAACCGAGGAAGTCAACAAGGACGGCAAGACCTTCACCCGCGTGCTCAACGCCGACCGCAGCTACACCACGCCCGACGGCGGTGAATTGACCCTGCCCGGGCGCAGCCTGTTGTTCGTCCGCAACGTGGGCCATCTGACGACCAGCGACGCGATTCTCGTGGACGGAGGTGACGGTCAGGAAAAAGAAGTGTTCGAGGGCATCATAGATGCAGTGTTCACCGGTCTGGCCGCAATCCACGGACTCAAAACCGGCGAAGCTAATGGCCCACTGACCAACAGCCGCACCGGTTCCATCTACATCGTCAAGCCGAAAATGCACGGTCCCGCGGAGGTTGCGTTCACTTGCGAGCTGTTCAGCCGCGTCGAAGACGTGCTGGGGTTGCCGCAGGGCACCTTGAAGGTCGGCATCATGGATGAGGAGCGGCGTACGACACTCAATTTGAAGGCGTGCATCAAGGCCGCCGCCGATCGGGTCGTGTTTATCAACACTGGCTTCTTGGACCGCACCGGCGACGAGATCCACACCTCAATGGAGGCCGGCCCGATGATTCGTAAGGGTGCGATGAAAAACAGCACCTGGATCAAAGCCTACGAGGACGCCAATGTTGACATCGGACTAGCCGCAGGCTTCAAGGGCAAAGCACAGATCGGCAAGGGCATGTGGGCAATGACCGAATTAATGGCTGATATGGTCGAGCAGAAGATCGGCCAGCCTAAGGCGGGCGCCACCACCGCGTGGGTACCCTCGCCCACTGCGGCCACGCTGCATGCGATGCACTACCACCAGGTCGACGTGGCTGCCGTGCAACAAGAACTGACCGGCCAGAGACGTGCCACCGTTGACCAGCTGTTGACCATTCCGTTGGCCAAGAAACTGGCCTGGGCTCCCGAGGAGATCCGCGAGGAGGTCGATAATGACTGTCAGTCCATCCTCGGTTATGTGGTGCGCTGGGTGGACCAGGGTATCGGTTGCTCGAAGGTGCCTGACATCCACAATGTGGCACTAATGGAGGACCGCGCCACCCTGCGGATCTCGAGCCAGTTGCTAGCAAACTGGCTGCGCCACGGCGTAATCACCAGCGAGGACGTGCGGGCCAGCCTGGAACGGATGGCGCCGTTAGTCGATCAGCAAAACGCCGAAGACCCAGCATATCGCCCGATGGCGCCTAATTTCGATGACAGCATCGCGTTCCTAGCGGCGCAGGAACTGATACTGTCCGGCGCACAACAGCCCAACGGCTATACCGAGCCGATCCTGCATCGCCGTCGTCGCGAATTCAAGGCACAGAACCGGTGACGGATGC

Protein Sequence 

>ML2069_GlcB_protein
IACRRGICASPVCFTTSSTTKPCLAPTSTQTASGRASPRSSPTSPRKTKVC_TPAMSCRPRLTNGTAIV_SSHSTWMLIGSSSSISAICCLNPMTSPSAPQE_TTRSP_PPARSWWCRYLTHGSHSTPPTPAGAPFTTLYMAPTPYRKPREPKRALSTTRFAATR_SPTHASLWIRPSRWLLTHGLTLRE_ASSTASFRSPSARIPPD_PVPKSLSATIASCDPPTGRCCWPITACTSRS_STRNHQ_ARLTPSASRM_SWNRPSPRSWTSKTQSLPSTPTTRYAATATGSA_TKVT_PRKSTRTARPSPACSTPTAATPRPTAVN_PCPGAACCSSATWAI_RPATRFSWTEVTVRKKKCSRAS_MQCSPVWPQSTDSKPAKLMAH_PTAAPVPSTSSSRKCTVPRRLRSLASCSAASKTCWGCRRAP_RSASWMRSGVRHSI_RRASRPPPIGSCLSTLASWTAPATRSTPQWRPAR_FVRVR_KTAPGSKPTRTPMLTSD_PQASRAKHRSARACGQ_PN_WLIWSSRRSASLRRAPPPRGYPRPLRPRCMRCTTTRSTWLPCNKN_PARDVPPLTSC_PFRWPRNWPGLPRRSARRSIMTVSPSSVMWCAGWTRVSVARRCLTSTMWH_WRTAPPCGSRASC_QTGCATA_SPARTCGPAWNGWRR_SISKTPKTQHIARWRLISMTASRS_RRRN_YCPAHNSPTAIPSRSCIAVVANSRHRTGDGC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding GlcB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

7 show intermediate predicted evidence for PPIs

24 show weak predicted evidence for PPIs

View all pooled AlphaFold results for GlcB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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