secA2
mL2082c
POSSIBLE PREPROTEIN TRANSLOCASE ATPase SECA2
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2472776 – 2475112
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2082c_secA2_dna
TTAACCTGTGTCTAAGACGCCTCGCACTCAGCCTGGCCGTCTGAGTAGTCGATTTTGGCGGCTACTCGGCGCCAGCACGGACAAGAACCTAAACTACTCTTCCGCTGAGGTCACTGCTGCGGCGGCTTACCACAAGGAAGCTGCCGATCTGGGCGATGAGCAGTTGCGCAAGGCGTGCGGGTTGCTCAATCTCAACGATCTCGCCGATTCTCGCGACGTCCCCCAATTCCTTGCCATCGTCCGGGAAGCGTCTGAGCGGTCCACGGGTTTGAGGCCTTTTGATGTGCAGTTACTCGGGGCGCTACGCATGCTTGCTGGTGACGTGATCGAGATGGCCACCGGTGAGGGCAAAACTCTCGCCGGCGCGATTGCGGCGGCCGGATACGCCCTTGCCGGCCGGCATGTGCACGTCGTGACGATCAACGATTATTTGGCCCGCCGTGATGCGGAATGGATGGGCCCGCTGCTCGAGGCCATAGGCCTGACGGTGGGCTGGATCACCGCGGAGTCAACACGCGAGGACCGTAAGGCTGCTTACGGCTGCGACGTCACCTACGCCTCGGTCAACGAGATCGGTTTTGATGTGCTGCGCGATCAGTTGGTGACCGACGTCGACGACCTGGTATCGCCCCATCCTGATGTGGCCCTTATCGACGAGGCCGACTCCGTGCTGGTCGATGAGGCATTGGTGCCGCTCGTGTTAGCCGGTGCCACGCATCGGGAGACGCCGCGGCTCGAGATCATCAAGCTGGTCGGCGAGCTGTCCGCCGAATCCGATTATGACACCGATTCCGACAGCCGCAACGTCCACCTGACTGATGTCGGGGCGCGCAAGGTCGAAAAGGCGCTCGGTGGCATCGATCTGTACTCCGAGGAACACGTTGGCACCACGTTGACCGAGGTAAACGTCGCATTGCACGCCCATGTGCTGTTGCAGCGTGACGTGCACTACATTGTCCGAGACGACGCGGTACATCTAGTCAACGCCTCCCGCGGCCGCATCGCACAGCTGCAACGCTGGCCGGACGGCCTGCAGGCCGCGGTCGAGGCGAAGGAGGGCATCGAGACCACCGAGACCGGCGAAGTGCTCGATACCATCACAGTGCAGGCACTGATCAATCGTTACGCCACTGTGTGCGGTATGACCGGCACAGCGCTGGCCGCTGGTGAGCAGTTACGCCAGTTCTACAAGCTCGGTGTGTCACCGATACCGCCGAATACTCCCAACATTCGTGACGACGCGTCGGACCGAGTCTACATCACCGCGGCCGCCAAGAATGACGCGATCGTGGCGCACCTCGCTGAGGTGCACGAAACGGGTCAACCGGTGCTGGTCGGGACCCGTAACGTTGCCGAATCCGAGGAGCTGCACGAGCGGTTGCTGCGACACGGCGTGCCCGCGGTCGTGCTCAACGCTAAAAACGATGCCGAAGAAGCGCGGTTCATCGCGGAAGCCGGCAAATTCGGTGCGGTCACCGTGTCCACCCAGATGGCTGGGCGCGGCACCGATATCCGTCTTGGTGGATCTGACGAATCCGACCACGACAGGGTCGTCGAGCTAGGTGGGCTGCACGTGGTCGGCACCGGGCGGCACCATACCGAGCGATTGGATAACCAGTTGCGTGGCCGGGCTGGGCGCCAGGGCGATCCTGGATCGTCGGTGTTCTTCTCCAGCTGGGAAGATGATGTCATTGCGGCCAACCTCGACCGCAACAAGTTGCCGATGCAGACCGACGAGGATGGCCGCATCATCAGCCTCAAAACCACCGGTTTGCTTGACCATGCCCAGCGTGTTGCGGAGGGTCGGCTGCTGGACGTGCATGCGAATACCTGGCGCTACAACCAGTTGATAGCCCAGCAGCGCGCCATCATCGTGGATCGGCGAAACGCGTTGCTGAGTAGTGCAACCGCGCGCGAGGAGCTCGCAGAGCTGGCGCCCAAGCGTTACGAGGAGCTGGCTCAGGCACTGCCCAAAGAGGAGGCCGAAGAACGGCTCGAGACGATCTGCCGATTGATCATGTTGTATCACCTCGACCGTGGCTGGGCCGATCATCTGGCGTATCTGGCTGACATTCGTGAAAGTATCCATTTGCGCGCGCTCGGCCGGCAAAGTCCTCTGGACGAGTTTCACCGGTTGGCGGTGAACGCGTTTGCTTTGCTGGCCGCCGACGCGATCGAGGCGGCCCAGCAGACGTTCGAAACCGCGAATATCCTTGATGGGGCGCCAGGACTGGATTTGTCCAAACTAGCGCGGCCGACGTCGACGTGGACCTACATGGTCAATGATGCCCCGCTGTCCGATGACACGCTTTCTCCCTTGAGCCTACCCGGGGTTTT

Protein Sequence 

>ML2082c_SecA2_protein
LTCV_DASHSAWPSE_SILAATRRQHGQEPKLLFR_GHCCGGLPQGSCRSGR_AVAQGVRVAQSQRSRRFSRRPPIPCHRPGSV_AVHGFEAF_CAVTRGATHACW_RDRDGHR_GQNSRRRDCGGRIRPCRPACARRDDQRLFGPP_CGMDGPAARGHRPDGGLDHRGVNTRGP_GCLRLRRHLRLGQRDRF_CAARSVGDRRRRPGIAPS_CGPYRRGRLRAGR_GIGAARVSRCHASGDAAARDHQAGRRAVRRIRL_HRFRQPQRPPD_CRGAQGRKGARWHRSVLRGTRWHHVDRGKRRIARPCAVAA_RALHCPRRRGTSSQRLPRPHRTAATLAGRPAGRGRGEGGHRDHRDRRSARYHHSAGTDQSLRHCVRYDRHSAGRW_AVTPVLQARCVTDTAEYSQHS_RRVGPSLHHRGRQE_RDRGAPR_GARNGSTGAGRDP_RCRIRGAARAVAATRRARGRAQR_KRCRRSAVHRGSRQIRCGHRVHPDGWARHRYPSWWI_RIRPRQGRRARWAARGRHRAAPYRAIG_PVAWPGWAPGRSWIVGVLLQLGR_CHCGQPRPQQVADADRRGWPHHQPQNHRFA_PCPACCGGSAAGRACEYLALQPVDSPAARHHRGSAKRVAE_CNRARGARRAGAQALRGAGSGTAQRGGRRTARDDLPIDHVVSPRPWLGRSSGVSG_HS_KYPFARARPAKSSGRVSPVGGERVCFAGRRRDRGGPADVRNREYP_WGARTGFVQTSAADVDVDLHGQ_CPAVR_HAFSLEPTRGF

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding SecA2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

72 show weak predicted evidence for PPIs

View all pooled AlphaFold results for SecA2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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