fprB
mL2134c
PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2535820 – 2537487
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2134c_fprB_dna
AGTTTCTATGCCGTATATCATCACCCAGTCGTGCTGCAACGATGGGTCTTGTGTGTTTGCTTGCCCGGTGAATTGCATTCACCCAACACCGGACGAGCCGGGGTTCGCTACTTCGGAGATGCTTTATATCGATCCTGTAGCCTGTGTGGATTGTGGCGCCTGTGTGAGCGCCTGTCCGGTTGGTGCTATTGCATCCGACACCCGGTTGGCGCCTAAGCAGCTGCCGTTTATCGAGATCAACGCGTCGTATTACCCGGCGCGGCCCATTGACCTGAAACTTCCGCCGACCTCGAAGTTGGCTCCGGTCATCCCGGCCGCACAGGTACATGTTCGTCGTCGCCCGCTGACCGTGGCCATCGTCGGGTCCGGTCCAGCGGCAATGTATGCTGCCGATGAGCTGCTTACTCAACCTGGGGTGTGGGTTAATGTGTTCGAGAAGTTACCTACCCCTTACGGTTTGGTTCGCGCCGGGTTGGCGCCCGATCACCAGAACACGAAAAAGGTGACTGAGCTCTTCGACCGGGTCGCCGAGCATCGCCGCTTCCGTTTTTTTCTCAACGTCGAGATAGGTAGGCACTTGAGCCACGACGAATTGTTGGCCCATCACCATGCTGTGCTGTATGCGGTCGGTGCGCCTGATGATCGTCGTCTGAACATCGACGGGATGGGTATCCCGGGTACTGGAACCGCTACCGAGCTAGTAGCCTGGATCAACGCTCATCCCGACTTTGCTTATCTACCAGTCGATCTCAGTCATGAACGCGTAGTAGTCATCGGTAATGGCAATGTCGCCCTCGATGTGGCACGGTTGCTCACTGCCGATCCGGACAACTTGGCCCGGACCGATATTTCCGAGTTTGCACTGCACGTGTTGGGCGGCTCCGCGGTCCGCGAAGTGGTGGTCGCCGCCCGTCGTGGCCCCGCGCACTCGGCGTTCACCTTGCCCGAGCTGATCGGGTTGAAGGCCACGTCTGAGGTGGTACTCGACGCCGGTGACCGCAAGTTGGTGGAAGGTGATTTCGCGACCGTATCAGACAGTTTGACCAGAAAGAAACTGGAGGTCTTGAGCAGTCTTGTTGATAGTTCGAAGCCGACTTCGCGGCGGCGAATCCGGCTGGCCTATCAGCTCACGCCCAAGCGCGTGCTTGGTAACCAGCGCGCTACCGGTGTTGAGTTCTCGGTTACCGGCACCGAAGAATCACGTCGGTTCGATGCGGGCCTGGTGCTGACATCGGTTGGTTACCGCGGCAAACGGATTCGCGATCTGCCATTCGACGAGGAAGCGGCGGTAATCCCGAATGACGGTGGCCGTGTGGTCGACCCGAGTCGGGGCCGTCCGATGCCCGGCGCCTATGTGGCTGGCTGGATCAAACGTGGACCAACAGGCTTCATCGGCACTAACAAGTTGTGCTCGGTTCAAACCGTTCAGGCCGTGGTCGCCGACTTCAACGCCGGCTGGCTGACCGACCCGGTGGCTGAGCCGGCGGAGCTAGCCAAGCTGGTGCACGCCCGCCAACCCGATACTGTCGACTCCGTGGGATGGCGGGCCATCGACGCCGCCGAGATCGCGCAGGGCAGTACCGAAGGCCGGCCACGCCGCAAGTTCACCGATGTCGCCGACATGCTGGCGGTTGCAGCCGGCGCGCCGCCGCTGCGGCTGCGTGCCCT

Protein Sequence 

>ML2134c_FprB_protein
SFYAVYHHPVVLQRWVLCVCLPGELHSPNTGRAGVRYFGDALYRSCSLCGLWRLCERLSGWCYCIRHPVGA_AAAVYRDQRVVLPGAAH_PETSADLEVGSGHPGRTGTCSSSPADRGHRRVRSSGNVCCR_AAYSTWGVG_CVREVTYPLRFGSRRVGARSPEHEKGD_ALRPGRRASPLPFFSQRRDR_ALEPRRIVGPSPCCAVCGRCA__SSSEHRRDGYPGYWNRYRASSLDQRSSRLCLSTSRSQS_TRSSHR_WQCRPRCGTVAHCRSGQLGPDRYFRVCTARVGRLRGPRSGGRRPSWPRALGVHLARADRVEGHV_GGTRRR_PQVGGR_FRDRIRQFDQKETGGLEQSC__FEADFAAANPAGLSAHAQARAW_PARYRC_VLGYRHRRITSVRCGPGADIGWLPRQTDSRSAIRRGSGGNPE_RWPCGRPESGPSDARRLCGWLDQTWTNRLHRH_QVVLGSNRSGRGRRLQRRLADRPGG_AGGASQAGARPPTRYCRLRGMAGHRRRRDRAGQYRRPATPQVHRCRRHAGGCSRRAAAAAACP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding FprB with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

54 show weak predicted evidence for PPIs

View all pooled AlphaFold results for FprB

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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