ML2135c
mL2135c
possible transmembrane protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2537503 – 2538528
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2135c_ML2135c_dna
GGCTGTGATGGCCAGGACGCGAATGGTTCGGCGTTGGCGCAACAACATGGAGGTGCGCGATGACACCGACTATGTGGGCATGCTCACCACATTGTCTGAGGGGTCGGTGCGGCGCAACTTCAATCCGTACACCGATATCGATTGGGAATCACCAGCGTTCGCGGTAAAGGACAACGACCCGCGGTGGATCTTGCCGGATACTGACCCGCTGGGTCGTCATCCCTGGTATCTGGCGCAGCCGGAACAACGCAAGATCGAGATCGGGATGTGGCGTCAGGCCAACGTGGCCAAGGTTGGGCTGCACTTCGAATCCATTTTGGTCCGAGGTCTGATGAATTACACGTTTTGGATGCCGAACGGATCACCGGAGTATCGGTATTGCTTGCATGAATGTGTTGAAGAGTGCAACCACACGATGATGTTCCAGGAAATGGTCAACCGCGTTGGCGCGGACGTTCCGGGCATGCCGCGCAGACTGCGTTGGCTTTCGCCGTTGGTGCCGTTGGTCGCCGGGCCGTTGCCGGTGGCTTTCTTCATCGGTGTGCTCGCCGGTGAGGAACCCATCGACCACATGCAGAAGAACGTGCTACGCGAAGGCAAGTCGCTGCATCCGATCATGGAGAGGGTGATGGCCATTCACGTGGCCGAGGAGGCGCGACACATCTCCTTCGCTCACGAGTTCTTGCGTAAGCGGTTAACGCACTTGACCAAGCGACAGCTTTTCTGGGTCTCGTTGTATTATCCACTAACGATGCGGGTGTTGTGTAACGCAATCATGGTTCCGCCCAAGGCTTTCTGGCAGGAGTTCAACATTCCGCGTGAAGTCAAGAAGGAGCTGTTCTTCCGGTCACCGGAGTCACGAAAATTGTTGCGTGACATCTTCGCCGATGTCCGGATGCTGGCCTACGACACCAGGCTTATGGAGACGCGCTCTGCGCGGCTCATGTGGCATATATGCAAGATCGATGGGCAGCCGTCGCGTTATCGTGGTGAGCCGCAGCGTCAGCACCCGGCGACGACATCTGC

Protein Sequence 

>ML2135c_ML2135c_protein
GCDGQDANGSALAQQHGGAR_HRLCGHAHHIV_GVGAAQLQSVHRYRLGITSVRGKGQRPAVDLAGY_PAGSSSLVSGAAGTTQDRDRDVASGQRGQGWAALRIHFGPRSDELHVLDAERITGVSVLLA_MC_RVQPHDDVPGNGQPRWRGRSGHAAQTALAFAVGAVGRRAVAGGFLHRCARR_GTHRPHAEERATRRQVAASDHGEGDGHSRGRGGATHLLRSRVLA_AVNALDQATAFLGLVVLSTNDAGVV_RNHGSAQGFLAGVQHSA_SQEGAVLPVTGVTKIVA_HLRRCPDAGLRHQAYGDALCAAHVAYMQDRWAAVALSW_AAASAPGDDIC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2135c with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

33 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2135c

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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