ML2143
mL2143
POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2543933 – 2545672
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2143_ML2143_dna
GACGGCGGCGTAATCATCCGGGCCGTTTGGCCTCTATACCAGGCCTCCGGACCCGCACCGGCTCGCGTAACCAGCATCCAGGCATTGCGAACTACCCGGCCGACAGCTCTGACTTTCGGCCAGCCCAGCAACGGAGAGCGCTGGAACAGCGCGAACAACAAGCCGGGCAGTTGGACCCAGCGCGCCGCTCGCCGTCGATGCCCAGCGCCAACCGCTATCTCCCGCCCCTGGGCCAGCAGCAGTCAGAACCCCAACACAACAGTGCGCCACCATGCGGTCCGTACCCTGGTGAACGAATTAAGGTCACTCGCGCTGCCGCACAGCGAAGCCGTGAAATGGGCTACCGAATGTACTGGATGGTTCAGCGTGCCGCCACCGCTGACGGCGCTGACAAATCCGGGCTAACTGCATTGACGTGGCCGGTGGTCACGAACTTTGCGGTAGACTCCGCAATGGCCGTTGCACTGGCCAACACTTTGTTCTTCGCCGCGGCCAGCGGGGAGAGCAAATCCAAAGTCGCGCTGTACCTGCTGATCACCATCGCTCCGTTCGCGGTGATCGCGCCGCTCATCGGTCCGGCGCTAGACCGGCTGCAGCACGGCCGCCGCGTGGCGCTGGCAACCTCATTCGTGCTACGCACCGGATTGGCAACACTACTGATCATGAACTACGACGGCGCCACCGGCAGCTACCCGTCCATGGTGCTCTACCCGTGCGCGCTGGCCATGATGGTGTTGTCGAAATCGTTCAGCGTGCTGCGCAGCGCTGTCACACCAAGAGTGATGCCGCCCAGCATTGATCTGGTACGCGTCAATTCTCGGCTGACCGTGTTCGGTCTGCTCGGCGGCACCATCGCCGGTGGCGCCATCGCGGCCGGTGTCGAGTTCGTCTGCGCCCACCTGTTCAAGCTGCCTGGCGCATTGTTCGTCGTCGCCGCGATCACGATCTCCGGCGCCTTGCTGTCAATGCGGATTCCGCGCTGGGTCGAGGTAACCGCGGGTGAAATTCCAGCCACTTTGAGCTATCGCTTGCATCGCAAACCATTGCGACAGAGCTGGCCTGAGGAAGTCAAGAAGGTCAGCGGCAGACTTCGACAACCGTTGGGCCGCAATATCATTACCTCGTTGTGGGGCAATTGCACCATCAAAGTGATGGTCGGCTTCCTATTCTTATATCCTGCGTTTGTCGCCAAAGAGCATCAAGCCAATGGCTGGGTCCAGCTGGGGATGCTGGGCTTGATCGGCACTGCTGCCGCGATCGGCAACTTCGCTGGCAATTTCACCAGCGCACGCCTGCAGCTGGGCAGGCCGGCCGTGCTGGTGGTGCGCTGCACAATCGCGGTCACTGTGTTAGCCTTAGCGGCGTCAGTGGCTGGCAATCTACTGATGACTACTATCGCTACCCTGATCACATCGGGATCTAGTGCAATTGCGAAGGCTTCGTTGGACGCCTCGTTGCAAAATGATTTGCCTGAGGAGTCACGAGCATCGGGATTCGGCCGTTCAGAATCAACGCTGCAACTAGCATGGGTGCTAGGCGGAGCACTAGGCGTGATGGTGTACACCGATTTGTGGGTCGGATTCACCGCGGTCAGTGCCTTGCTGATCCTAGGTCTAGCGCAAACCGTCGTGAGCTTTCGCGGTGATTCGTTAATTCCAGGCCTCGGAGGTAATCGTCCGGTGATGATTGAGCAGGAGAGCATGCGCCGCGCCGCGGCGGTGAGTCCTCAATGAGACCCTG

Protein Sequence 

>ML2143_ML2143_protein
DGGVIIRAVWPLYQASGPAPARVTSIQALRTTRPTALTFGQPSNGERWNSANNKPGSWTQRAARRRCPAPTAISRPWASSSQNPNTTVRHHAVRTLVNELRSLALPHSEAVKWATECTGWFSVPPPLTALTNPG_LH_RGRWSRTLR_TPQWPLHWPTLCSSPRPAGRANPKSRCTC_SPSLRSR_SRRSSVRR_TGCSTAAAWRWQPHSCYAPDWQHY_S_TTTAPPAATRPWCSTRARWP_WCCRNRSACCAALSHQE_CRPALIWYASILG_PCSVCSAAPSPVAPSRPVSSSSAPTCSSCLAHCSSSPRSRSPAPCCQCGFRAGSR_PRVKFQPL_AIACIANHCDRAGLRKSRRSAADFDNRWAAISLPRCGAIAPSK_WSASYSYILRLSPKSIKPMAGSSWGCWA_SALLPRSATSLAISPAHACSWAGRPCWWCAAQSRSLC_P_RRQWLAIY__LLSLP_SHRDLVQLRRLRWTPRCKMICLRSHEHRDSAVQNQRCN_HGC_AEH_A_WCTPICGSDSPRSVPC_S_V_RKPS_AFAVIR_FQASEVIVR__LSRRACAAPRR_VLNETL

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2143 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

5 show intermediate predicted evidence for PPIs

64 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2143

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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