ercC3
mL2157
PROBABLE DNA HELICASE ERCC3
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2559343 – 2560992
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2157_ercC3_dna
ACGGGCCGTTGATAGTGCAGTCCGATAAAACGGTGCTGCTCGAAGTGAACCATAAGCTAGCCGATGCGGCACGTGCAGCCATAGCACCGTTCGCCGAGCTGGAACGCGCACCCGAACACGTACACACCTACCGCATCACACCACTAGCGTTGTGGAACGCCCGCGCCGCAGGTCATGACGCCGAACAAGTCGTCGACACGTTGATCAGTCATGCGCGCTACGCAGTGCCACAGCCTCTGCTGGTCGACATCGTCGACACCATGGCCCGCTATGGGCGGCTGCAACTGGTCAAGAATCCCGCCCACGGCCTGACGCTGGTAAGCCTGGATCGCACGGTACTGGAGGAGGTGTTACATAACAAGAAGATCGCACCGATGGTGGGCGGCCGCATCGACGACGACACAGTCGTCGTCCATCCCAGCGAACGTGGCCGGATCAAACAGCTTTTGCTTAAGATCGGTTGGCCCGCAGAGGATCTCGCTGGTTACGTGGATGGTGAGGCGCACCCGATTATCCTGCATCAGGACGGTTGGCAGCTGCGCGATTACCAGCGGCTAGCAGCCGATTCATTCTGGTCTGGCGGCTCCGGGGTGGTAGTGCTGCCATGTGGCGCTGGCAAAACGCTAGTGGGGGCGGCCGCGATGGCGAAAACCGGTGCGACGACGCTCATTTTAGTCACCAACATCGTGGTTGCCCGACAGTGGAAACGCGAGTTGATCACGCACACCTCGCTGACCGAGGACGAGATCGGCGAATACTCCGGAGAGCGCAAGGAAATCCGACCGGTGACCATCTCGACCTACCAGATGATCACCCACCGCACCAAAGGAGAGTATCGTCATCTGGAACTCTTCAATAGCCGCGACTGGGGCCTGATCATCTACGACGAGGTGCATCTGTTGCCCGCACCGGTGTTCCGGATGACCGCTGACCTGCAGTCCAAGCGGCGGCTGGGCCTGACCGCCACGTTGATCCGCGAAGACGGCCGCGAAGGTGACGTGTTTTCCCTGATCGGCCCGAAACGCTATGACACGCCGTGGAAGGACCTTGAGGAACAAGGCTGGATCGCGCCAGCAAAGTGCGTCGAAGTCCGGGTCACGTTGACGAATAACGAAAGGATGACCTACGCCACAGCCGAACCCGAAGAACGCTACCGTGTCTGCTCGACAGCGCATTCGAAGATTGCAGTGGTTAAGTCGGTGCTGAGCCGACACCCCGGCGAGCAAACCCTCGTGATCGGTGCCTACCTGGATCAGCTCAACGAACTTGGTTCCGAGCTCAACGCTCCAATCATTCAAGGATCAACGAGAACCAAAGAACGCGAAGCGCTATTCGACGCTTTCCGCCGCGGTGAAGTCTTCACACTGGTGGTCTCCAAGGTTGCCAACTTCTCCATAGATTTGCCGGAAGCCGCTGTTGCGGTACAAGTTTCGGGAACTTTTGGCTCACGTCAAGAGGAAGCGCAGCGGCTGGGCCGGTTGCTGCGACCTAAGGCCGACGGCGGTGGAGCGATCTTCTACTCCGTGGTTGCCCGCGACAGCCTGGACGCCGAATACGCCGCACACCGGCAGCGATTCTTAGCCGAGCAAGGCTACAGCTACATCATCCGCGACGCCGACGACCTGCTGGGCCCGGCGATCTAGCCTGACA

Protein Sequence 

>ML2157_ErcC3_protein
TGR__CSPIKRCCSK_TIS_PMRHVQP_HRSPSWNAHPNTYTPTASHH_RCGTPAPQVMTPNKSSTR_SVMRATQCHSLCWSTSSTPWPAMGGCNWSRIPPTA_RW_AWIARYWRRCYITRRSHRWWAAASTTTQSSSIPANVAGSNSFCLRSVGPQRISLVTWMVRRTRLSCIRTVGSCAITSG_QPIHSGLAAPGW_CCHVALAKR_WGRPRWRKPVRRRSF_SPTSWLPDSGNAS_SRTPR_PRTRSANTPESARKSDR_PSRPTR_SPTAPKESIVIWNSSIAATGA_SSTTRCICCPHRCSG_PLTCSPSGGWA_PPR_SAKTAAKVTCFP_SARNAMTRRGRTLRNKAGSRQQSASKSGSR_RITKG_PTPQPNPKNATVSARQRIRRLQWLSRC_ADTPASKPS_SVPTWISSTNLVPSSTLQSFKDQREPKNAKRYSTLSAAVKSSHWWSPRLPTSP_ICRKPLLRYKFRELLAHVKRKRSGWAGCCDLRPTAVERSSTPWLPATAWTPNTPHTGSDS_PSKATATSSATPTTCWARRSSLT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ErcC3 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

2 show intermediate predicted evidence for PPIs

20 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ErcC3

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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