desA1
mL2185
PROBABLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA1 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) (PROTEIN DES)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2599223 – 2600239
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2185_desA1_dna
CCGAGCTGACCGACCTACAGCTGCTGCACGAGCTCGAACCGGTCGTGGAGAAGTACATGAACCGTCATGAACGCCTACACAAGAACTGGAATCCGCACGACTATATCCCGTGGTCGGATGGCAAGAACTTCTACGCTCTCGGCGGTCAGGATTGGGACCCCGAGCAGAGCCAGCTCTCCGATGTCGCCCAAGTAGCGATGGTACAGAACCTGGTCACCGAGGACAACCTGCCGTCGTATCACCGAGAAATCGCGATGACCATGGGCATGGACGGTGCATGGGGGCAGTGGGTCAACCGCTGGACAGCCGAGGAAAACCGGCACGGAATCGCGCTGCGCGACTATCTGGTGGTGACCCGCGCGGTCGATCCGGTGGAGCTAGAGAAACTACGCATCGAGGTAGTCAACCGGGGTTTCAGCCCGGGCCAGAATCACCAAGGCGGACTCTTCGCCGACACCCTGTTCGACTCGATCCTCTACGTCACATTCCAGGAGCTGGCTACCCGCGTCTCGCACCGCAACACGGGTAAGGCCTGCAACGAGACGATCGCTGACCAGCTGCTCGCTAAAATATCGAGCGATGAAAACCTGCACATGATCTTCTACCGGGACGTCAGCGAAGCTGGCATAGAGCTCGCACCCAACCTTGCGATCAAGGCACTGCACAAGATCCTGCACAACTTTAAGATGCCGGGATTCCTGGTTCCTGAGTTCCGGCGTAAGGCCGTGATAATTGCCGTCGGTGGCGTCTACGACATTCGGATCCACCTTGACGAGGTGGTCATGCCGGTGCTCAAAAAATGGCGGATCTTGGAGCGCGAAGACTTCAGCGGCGAGGGTACACGGTTGCGTGACGAAATCGGCGAGCATCTTACAGAGCTTGAGGCCGCGTGCGACAAGTTCGAAGTCTCCAAGCAGCGCTACATTGAACGCGAAGCCCGCCGGACTGAGAAAATCACCGCACGCAAGGTGCTATCTACCGAAGGCACGCTGAGGATGAGTGGGCGGTAGTTGACCA

Protein Sequence 

>ML2185_DesA1_protein
PS_PTYSCCTSSNRSWRST_TVMNAYTRTGIRTTISRGRMARTSTLSAVRIGTPSRASSPMSPK_RWYRTWSPRTTCRRITEKSR_PWAWTVHGGSGSTAGQPRKTGTESRCATIWW_PARSIRWS_RNYASR_STGVSARARITKADSSPTPCSTRSSTSHSRSWLPASRTATRVRPATRRSLTSCSLKYRAMKTCT_SSTGTSAKLA_SSHPTLRSRHCTRSCTTLRCRDSWFLSSGVRP__LPSVASTTFGSTLTRWSCRCSKNGGSWSAKTSAARVHGCVTKSASILQSLRPRATSSKSPSSATLNAKPAGLRKSPHARCYLPKAR_G_VGGS_P

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding DesA1 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

1 protein shows strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

23 show weak predicted evidence for PPIs

View all pooled AlphaFold results for DesA1

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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