ML2186
mL2186
POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2600283 – 2601437
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2186_ML2186_dna
CTCCGATGGCCGGAGTAACGAACGTCACATTCCGGACACTGTGCCGTGAATTTGGTTCAACGCGTGGCAACCTGCTGCGCCCAGCTCCACCGCACTTGCGATCGCCACTAGAACAATCGCAGGTAGGCACCATCAGCGGACTGTACGTCTGCGAAATGGTGACCGCGCGTGCACTAGTCGAGCGAAATGCAGTCACGATACACATGACCACGTTCGCACCGGACGAGTCGCCCCGGTCGTTGCAGCTCTACACCGTGGACCCGGCTACCACGTACACGGCCGCCAAGATGGTCGCTGACGAAGGTTTGGCCGATCACATCGATATGAATTTCGGCTGCCCGATGCCCAAGGTCACCAGACGCGGCGGCGGGGCAGCGCTGCCATACAAACGGCGACTGTTTGGCCAGATCGTCGCTGCCGCTGTGCGTGCTACCGAAGGCACCAAAATACCGGTGACCGTCAAGTTCCGCATCGGCATCGACGACGAGCATCACACCCACCTAGATGCCGGCCGTATCGCCGAAGCTGAGGGCGCAGCCGCGGTCGCATTGCACGCCCGGACGGCGGCTCAACGCTACTCCGGCACCGCTGATTGGGCACAGATCGCCCAACTCAAACAGCAGGTAAGGACGATTCCTGTGCTCGGCAATGGGGACATCTACGACGCGAGCGACGCGCTGGCCATGATGGCCGTCACTGGGTGCGACGGCGTGGTCATCGGCCGCGGCTGCCTGGGCCGTCCGTGGCTGTTCGCCGAGCTGTCGGCCGCGTTCACCGGCAGACCTGCCCCCGCCCCGCCCACACTCGGCGAAGTCGCCGAAATCGTCCGTCGGCACGGCAAACTGCTAGTCGCCCATTTCGGCGAAGACAAAGGCATGCGCGACATCCGCAAACACATCGCGTGGTACCTGCACGGCTTTCCCGCCGGATCCGAATTGCGAAACGCACTGGCACTGGTCAAAACGCTCGATGAACTTGACTGCCTATTAAACCGGTTGGACGGAGCTGTTCCGTTCCCGGATGCCGCGATCGGACCCCGGGGTAGGCAGGGTTCACCCGCCTGGGTGGCATTGCCCGACAGCTGGCTGACTGACCCTGACGACTGCACAGTGCCGATCGGCGCCGACATCATGGAATCTGGTGGCTGAATCGAAA

Protein Sequence 

>ML2186_ML2186_protein
LRWPE_RTSHSGHCAVNLVQRVATCCAQLHRTCDRH_NNRR_APSADCTSAKW_PRVH_SSEMQSRYT_PRSHRTSRPGRCSSTPWTRLPRTRPPRWSLTKVWPITSI_ISAARCPRSPDAAAGQRCHTNGDCLARSSLPLCVLPKAPKYR_PSSSASASTTSITPT_MPAVSPKLRAQPRSHCTPGRRLNATPAPLIGHRSPNSNSR_GRFLCSAMGTSTTRATRWP_WPSLGATAWSSAAAAWAVRGCSPSCRPRSPADLPPPRPHSAKSPKSSVGTANC_SPISAKTKACATSANTSRGTCTAFPPDPNCETHWHWSKRSMNLTAY_TGWTELFRSRMPRSDPGVGRVHPPGWHCPTAG_LTLTTAQCRSAPTSWNLVAESK

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2186 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

62 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2186

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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