ML2197
mL2197
Possible integral membrane protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 2611551 – 2612036
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2197_ML2197_dna
TCAATAACACCACCACCGGAGTAGAGGTCGTCGATGTTCGCGGACCACGATTTGCTGCATGGGTTACGGCCGCAGTTCTGCAGACCGTCCTGATCATTTCGGTGGTCAGTCCGCTGGCGGCCGCGTTACTGTTGGTCCTGCAGGCCGTAGTTTTTGCCACGGGCACTCTCGGCGGCCCGCGCCGGCACCCATACGGACGGGTGTTCGCCGCCCTCGTGGCGCCTCGGCTGGGTCCGGTGAAAGAGCGCGAACCGGTGCCACCGTTAAAGTTCGCCCAACTGCTCGGCTTCGTCTTCGTGGTTTGCGGTGTTACCGGATTCGCCGCCGGCGCTTTCTTGGTGGGAGTCATCGCTACGGCAGCTGCATTAGTGGCCGCTTTCCTCAACGCAGCGTTCGGCATCTGTCTGGGCTGTCAGCTCTACCCGGTTGTGGTGTGGTTTCGACGCACTGCCGCTCCACGTAACCGTAACCCTGGTTGACCACCCC

Protein Sequence 

>ML2197_ML2197_protein
SITPPPE_RSSMFADHDLLHGLRPQFCRPS_SFRWSVRWRPRYCWSCRP_FLPRALSAARAGTHTDGCSPPSWRLGWVR_KSANRCHR_SSPNCSASSSWFAVLPDSPPALSWWESSLRQLH_WPLSSTQRSASVWAVSSTRLWCGFDALPLHVTVTLVDHP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2197 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

4 proteins show strong predicted evidence for PPIs

6 show intermediate predicted evidence for PPIs

58 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2197

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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